CATH Domain 2m14A00

×

Network disruptions

We have been experiencing disruptions on our local network which has affected the stability of these web pages. We have been working with IT support team to get this fixed as a matter of urgency and apologise for any inconvenience.

CATH Classification

Level	CATH Code	Description
	2	Mainly Beta
	2.30	Roll
	2.30.29	PH-domain like
	2.30.29.30	Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)

Domain Context

CATH Clusters

Superfamily	Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)
Functional Family	Transcription initiation factor TFIIH subunit

Enzyme Information

UniProtKB Entries (1)

RAD4_YEAST

Saccharomyces cerevisiae S288C

DNA repair protein RAD4

PDB Structure

PDB	2M14
External Links	PDBSum Proteopedia
Method	SOLUTION NMR
Organism
Primary Citation	Structural and functional evidence that Rad4 competes with Rad2 for binding to the Tfb1 subunit of TFIIH in NER. Lafrance-Vanasse, J., Arseneault, G., Cappadocia, L., Legault, P., Omichinski, J.G. Nucleic Acids Res.