CATH Domain 2g81E02

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CATH Classification

Level	CATH Code	Description
	2	Mainly Beta
	2.40	Beta Barrel
	2.40.10	Thrombin, subunit H
	2.40.10.10	Trypsin-like serine proteases

Domain Context

CATH Clusters

Superfamily	Trypsin-like serine proteases
Functional Family	Cationic trypsin

Enzyme Information

3.4.21.4

Trypsin.

based on mapping to UniProt P00760

Preferential cleavage: Arg-|-Xaa, Lys-|-Xaa.

-!- Belongs to peptidase family S1. -!- Formerly EC 3.4.4.4.

UniProtKB Entries (2)

P00760	TRY1_BOVIN Bos taurus Cationic trypsin
Q9S9H8	Q9S9H8_VIGUN Vigna unguiculata Serine protease ISO-inhibitor FIV

PDB Structure

PDB	2G81
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Crystal Structure of the Bowman-Birk Inhibitor from Vigna unguiculata Seeds in Complex with {beta}-Trypsin at 1.55 A Resolution and Its Structural Properties in Association with Proteinases Barbosa, J.A.R.G., Silva, L.P., Teles, R.C.L., Esteves, G.F., Azevedo, R.B., Ventura, M.M., Freitas, S.M. Biophys.J.