CATH Domain 1jmjB01

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CATH Classification

Level	CATH Code	Description
	3	Alpha Beta
	3.30	2-Layer Sandwich
	3.30.497	Antithrombin; Chain I, domain 2
	3.30.497.10	Antithrombin, subunit I, domain 2

Domain Context

CATH Clusters

Superfamily	Antithrombin, subunit I, domain 2
Functional Family	heparin cofactor 2 isoform X1

Enzyme Information

UniProtKB Entries (1)

HEP2_HUMAN

Homo sapiens

Heparin cofactor 2

PDB Structure

PDB	1JMJ
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Crystal structures of native and thrombin-complexed heparin cofactor II reveal a multistep allosteric mechanism. Baglin, T.P., Carrell, R.W., Church, F.C., Esmon, C.T., Huntington, J.A. Proc.Natl.Acad.Sci.USA