The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Cysteine proteinases
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 83: Uncharacterized protein, isoform B

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 3 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Thiol-dependent ubiquitin-specific protease activity GO:0004843
Catalysis of the thiol-dependent hydrolysis of a peptide bond formed by the C-terminal glycine of ubiquitin and another protein.
4 Q8IQ26 (/ISS) Q8IQ27 (/ISS) X2JG37 (/ISS) X2JLM6 (/ISS)
Proteasome binding GO:0070628
Interacting selectively and non-covalently with a proteasome, a large multisubunit protein complex that catalyzes protein degradation.
1 Q8IQ27 (/IPI)
Lys48-specific deubiquitinase activity GO:1990380
Hydrolysis of Lys48-linked ubiquitin unit(s) from a ubiquitinated protein.
1 Q8IQ27 (/IDA)

There are 8 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Protein deubiquitination GO:0016579
The removal of one or more ubiquitin groups from a protein.
4 Q8IQ26 (/IMP) Q8IQ27 (/IMP) X2JG37 (/IMP) X2JLM6 (/IMP)
Protein deubiquitination GO:0016579
The removal of one or more ubiquitin groups from a protein.
4 Q8IQ26 (/ISS) Q8IQ27 (/ISS) X2JG37 (/ISS) X2JLM6 (/ISS)
Negative regulation of antimicrobial peptide production GO:0002785
Any process that stops, prevents, or reduces the frequency, rate, or extent of antimicrobial peptide production.
1 Q8IQ27 (/IMP)
Positive regulation of eclosion GO:0045805
Any process that activates or increases the frequency, rate or extent of eclosion.
1 Q8IQ27 (/IMP)
Negative regulation of calcium ion transport GO:0051926
Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of calcium ions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
1 Q8IQ27 (/IMP)
Negative regulation of peptidoglycan recognition protein signaling pathway GO:0061060
Any process that decreases the rate, frequency, or extent of the peptidoglycan recognition protein signaling pathway.
1 Q8IQ27 (/IMP)
Protein K48-linked deubiquitination GO:0071108
A protein deubiquitination process in which a K48-linked ubiquitin chain, i.e. a polymer of ubiquitin formed by linkages between lysine residues at position 48 of the ubiquitin monomers, is removed from a protein.
1 Q8IQ27 (/IDA)
Positive regulation of proteasomal protein catabolic process GO:1901800
Any process that activates or increases the frequency, rate or extent of proteasomal protein catabolic process.
1 Q8IQ27 (/IMP)

There are 0 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.