×

Network disruptions

We have been experiencing disruptions on our local network which has affected the stability of these web pages. We have been working with IT support team to get this fixed as a matter of urgency and apologise for any inconvenience.

View in Gene3D

CATH Superfamily 3.40.710.10

DD-peptidase/beta-lactamase superfamily

The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
DD-peptidase/beta-lactamase superfamily
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.

Browse Functional Families

ID Function Family (FunFam) Name Total Sequences Enzyme? Structure? Structural Representative PDB Sites? Alignment Diversity (0-100)
1
D-alanyl-D-alanine serine-type carboxypeptidase
608
3D
 5j8xA01 - 83.6
2
glutaminase kidney isoform, mitochondrial
485
3D
 5uqeC02 - 72.7
3
Peptidoglycan D,D-transpeptidase FtsI
371 - - 75.7
12
Beta-lactamase
358
3D
 6dpzB00 - 80.0
5
Glutaminase
345
3D
 3ihbB01 - 95.1
4
Peptidoglycan D,D-transpeptidase MrdA
343 - - 75.2
19
Beta-lactamase
298
3D
 6goaH00 - 86.7
6
Penicillin-binding protein 1B
231
3D
 5hldA03 - 84.5
7
D-alanyl-D-alanine endopeptidase
219 - - 57.3
8
Glutaminase, isoform E
137 - - 75.9
9
Glutaminase
127
3D
 3agfB01 - 55.7
33
Beta-lactamase
114
3D
 6b6fA00 - 70.8
10
Penicillin-binding protein 1A
111 - - 78.8
11
Penicillin-binding protein AmpH
105 - - 19.8
13
Penicillin-binding protein 1A
90 - - 70.7
14
Glutaminase
78
3D
 1u60D00 - 4.5
15
Serine beta-lactamase-like protein LACTB, mitochondrial
73 - - 38.3
16
serine beta-lactamase-like protein LACTB, mitochondrial
71 - - 38.3
17
Stage V sporulation protein D
69 - - 26.8
20
Penicillin-binding protein 1A
63
3D
 2zc6D00 - 91.9
18
D-alanyl-D-alanine carboxypeptidase dacB
61 - - 17.7
22
Penicillin-binding protein A
57
3D
 3uppB02 - 85.4
21
Penicillin-binding protein 1C
51 - - 82.3
23
D-alanyl-D-alanine carboxypeptidase DacF
44 - - 57.4
24
Penicillin-binding protein 2
43 - - 93.1
25
D-alanyl-D-alanine carboxypeptidase DacA
42 - - 74.2
26
Penicillin-binding protein 1
40 - - 80.5
27
Penicillin-binding protein 2
36 - - 71.3
28
Penicillin-binding protein 1A
34 - - 94.7
65
Peptidoglycan D,D-transpeptidase FtsI
33
3D
 5df9A03 - 1.1
29
Penicillin-binding protein 2
30 - - 8.6
51
Penicillin-binding protein 4
30
3D
 5txiB01 - 5.0
30
Penicillin-binding protein 1
29 - - 29.4
31
Penicillin-binding protein, putative
28 - - 49.2
32
Penicillin-binding protein 3
27 - - 71.7
35
Membrane peptidoglycan carboxypeptidase
22 - - 71.5
34
D-alanyl-D-alanine carboxypeptidase
22 - - 16.7
175
6-aminohexanoate-dimer hydrolase
21
3D
 2zmaA02 - 34.9
36
Penicillin-binding protein, 1A family
21 - - 8.1
38
Penicillin-binding protein, transpeptidase domain protein
20 - - 9.3
37
Penicillin-binding protein, 1A family
20 - - 7.7
40
Methicillin resistance protein FmtA
19 - - 5.1
95
Penicillin-binding protein 2x
19
3D
 2zc4E00 - 24.1
48
Probable peptidoglycan D,D-transpeptidase PenA
19
3D
 5kshB03 - 2.0
39
D-alanyl-D-alanine carboxypeptidase
19 - - 36.5
42
Penicillin-binding protein 1A
18 - - 86.3
41
Penicillin-binding protein 1A
18 - - 81.6
54
Penicillin-binding protein, transpeptidase domain protein
17
3D
 3vslB03 - 0.6
43
Penicillin-binding protein 2A
17 - - 16.0
44
D-alanyl-D-alanine carboxypeptidase
17 - - 8.7
71
Probable D-alanyl-D-alanine carboxypeptidase dacB2
17
3D
 4ryeD00 - 14.6
47
Glycosyl transferase family 51
16 - - 48.9
46
Transglycosylase
16 - - 72.6
45
Glutaminase
16 - - 9.1
49
Putative D-alanyl-D-alanine carboxypeptidase
15 - - 2.2
50
Putative D-alanyl-D-alanine carboxypeptidase
15 - - 23.5
55
Probable penicillin-binding protein dacB1
14
3D
 4pprA00 - 65.7
52
Penicillin-binding protein
14 - - 27.3
56
D-alanyl-D-alanine carboxypeptidase DacB
13 - - 14.9
57
D-alanyl-D-alanine carboxypeptidase
13 - - 3.1
59
Penicillin-binding protein 2
13 - - 0.0
58
Transglycosylase
13 - - 17.3
53
D-alanyl-D-alanine carboxypeptidase
13 - - 0.6
64
Penicillin-binding protein 2
12 - - 13.3
61
Penicillin-binding protein A
12 - - 82.9
66
Penicillin-binding membrane protein PbpB
12 - - 18.1
63
D-alanyl-D-alanine carboxypeptidase
12 - - 8.6
68
D-alanyl-D-alanine carboxypeptidase
12 - - 51.9
60
Penicillin-binding protein 1B
12 - - 8.4
67
Peptidoglycan D,D-transpeptidase MrdA
12 - - 0.0
62
Peptidase M15
12 - - 21.8
73
D-alanyl-D-alanine carboxypeptidase
11 - - 0.4
70
GLS isoform 12
11 - - 0.0
72
Alanine rich lipoprotein LppW
11 - - 0.0
85
Penicillin-binding protein 1A
11
3D
 3zgaB02 - 5.5
69
D-alanyl-D-alanine carboxypeptidase DacB
11 - - 28.9
79
6-aminohexanoate-dimer hydrolase
10
3D
 4gb7A00 - 74.4
77
Peptidoglycan D,D-transpeptidase FtsI
10 - - 7.8
75
Possible penicillin-binding lipoprotein
10 - - 2.3
74
Probable esterase/lipase lipP
10 - - 4.8
76
Penicillin-binding protein 2
10 - - 1.8
81
Penicillin-binding protein 1A
9 - - 21.3
78
PASTA domain-containing protein
9 - - 22.7
84
Peptidoglycan D,D-transpeptidase FtsI
9 - - 6.1
80
Conserved protein
9 - - 0.0
82
Penicillin-binding protein 1A
9 - - 8.6
83
D-alanyl-D-alanine carboxypeptidase
9 - - 6.6
86
Probable lipase lipe
8 - - 0.0
87
Penicillin-binding protein
8 - - 7.9
89
Peptidoglycan D,D-transpeptidase MrdA
8 - - 5.9
88
Cell division protein
8 - - 15.6
100
Penicillin-binding protein 1A
7
3D
 5cxwA00 - 13.2
91
Uncharacterized protein
7 - - 73.0
90
Penicillin-binding protein 2
7 - - 3.4
92
Cell division protein FtsI
Penicillin-binding protein 3
7 - - 14.4
102
Membrane carboxypeptidase/penicillin-binding protein
6 - - 4.1
94
Penicillin-binding protein 2B
PBP-2B
6 - - 4.6
104
Penicillin-binding protein 2
6 - - 16.1
103
Membrane carboxypeptidase/penicillin-binding protein
6 - - 11.7
96
Uncharacterized protein
6 - - 76.4
93
D-alanyl-D-alanine carboxypeptidase/D-alanyl-D-alanine-endopeptidase
6 - - 1.9
101
Penicillin-binding protein 1A
6 - - 8.7
98
PROBABLE ESTERASE LIPL
6 - - 0.0
99
Membrane peptidoglycan carboxypeptidase
6 - - 8.2
97
Uncharacterized protein
6 - - 70.7
111
Penicillin-binding protein 1C
5 - - 40.2
105
Penicillin-binding protein, putative
5 - - 12.9
106
Penicillin-binding protein 2X
5 - - 0.5
112
Penicillin-binding protein 1A
5 - - 9.3
109
Glutaminase
5 - - 10.2
107
Penicillin-binding protein, putative
5 - - 9.2
110
Putative D-alanyl-D-alanine carboxypeptidase
5 - - 13.1
108
Beta-lactamase
5 - - 0.0
114
D-alanyl-D-alanine carboxypeptidase
5 - - 8.3
113
Cell division protein/Peptidoglycan synthetase
5 - - 2.1
125
Penicillin-binding protein PbpC
4 - - 11.6
122
Serine-type D-Ala-D-Ala carboxypeptidase
4 - - 14.4
130
D-alanyl-D-alanine carboxypeptidase
4 - - 2.6
117
Penicillin-binding protein, putative
4 - - 5.2
119
Penicillin-binding protein 4
4 - - 6.9
123
D-alanyl-D-alanine carboxypeptidase
4 - - 4.3
118
D-alanyl-D-alanine carboxypeptidase
4 - - 7.7
124
Uncharacterized protein MT1414
4 - - 0.0
126
Penicillin-binding protein 1A
PBP-1A
4 - - 2.0
120
Penicillin-binding protein
4 - - 1.8
129
Penicillin-binding protein
4 - - 0.5
127
Penicillin-binding protein
4 - - 11.7
121
D-alanyl-D-alanine carboxypeptidase
4 - - 11.3
115
Penicillin-binding protein 2B
4 - - 7.1
116
Penicillin-binding proteins 1A and 1B
4 - - 0.0
128
Penicillin-binding protein 4B
4 - - 0.0
136
Stage V sporulation protein D
3 - - 6.5
133
Peptidase M15
3 - - 8.2
148
Penicillin-binding protein
3 - - 41.1
134
Beta-lactamase
3 - - 0.0
147
1A family penicillin-binding protein
3 - - 5.3
149
Cell division protein FtsI
3 - - 9.4
135
Penicillin-binding protein 1A
3 - - 0.0
132
Penicillin-binding protein 1B
3 - - 2.7
141
D-alanyl-D-alanine carboxypeptidase
3 - - 0.0
138
Putative penicillin-binding protein
3 - - 1.1
144
D-alanyl-D-alanine carboxypeptidase
3 - - 0.9
143
D-alanyl-D-alanine carboxypeptidase
3 - - 9.0
140
Glutaminase
3 - - 10.0
146
Penicillin-binding protein 4
3 - - 0.0
131
Putative lipoprotein YbbD
3 - - 0.0
142
Serine hydrolase
3 - - 10.9
145
Penicillin-binding protein
3 - - 9.7
137
Penicillin-binding protein 1A
3 - - 0.0
139
D-alanyl-D-alanine carboxypeptidase
3 - - 2.4
167
Peptidoglycan glycosyltransferase
2 - - 0.0
172
Peptidoglycan D,D-transpeptidase MrdA
2 - - 0.3
169
Cell division protein FtsI [Peptidoglycan synthetase]
2 - - 0.0
158
Uncharacterized protein
2 - - 11.0
161
Penicillin-binding protein 1B McrB, putative
2 - - 31.8
157
Penicillin-binding protein, 1A family
2 - - 10.1
173
ABC1 family protein
2 - - 2.5
159
Monacolin J acid methylbutanoyltransferase
2 - - 0.6
174
ABC1 family protein
2 - - 2.8
176
Penicillin-binding protein 1A
2 - - 48.9
151
Peptidoglycan D,D-transpeptidase FtsI
2 - - 0.0
168
Cell division protein FtsI [Peptidoglycan synthetase]
2 - - 0.0
170
Penicillin-binding protein 2
2 - - 0.0
153
Glutaminase like
2 - - 19.0
177
Glutaminase a
2 - - 24.0
162
Membrane transglycosylase and transpeptidase PBP1A
2 - - 0.0
165
Peptidoglycan transglycosylase and transpeptidase MrcA
2 - - 0.0
154
Uncharacterized protein
2 - - 33.0
156
Cell division protein ftsI
2 - - 0.0
171
Peptidoglycan transpeptidase
2 - - 0.0
150
Stage V sporulation protein D
2 - - 35.6
155
Penicillin-binding protein
2 - - 3.8
164
Penicillin-binding protein, class 1A
2 - - 0.0
163
Penicillin-binding protein 1C
PBP-1c
2 - - 1.5
152
Probable peptidoglycan D,D-transpeptidase PbpC
2 - - 0.0
160
D-alanyl-D-alanine carboxypeptidase
2 - - 0.0
166
Peptidoglycan transglycosylase and transpeptidase MrcA
2 - - 0.0
184
Penicillin-sensitive carboxypeptidase A
1 - - 0.0
195
Penicillin-binding protein 2
1 - - 0.0
192
Penicillin-binding protein
1 - - 0.0
183
Uncharacterized protein
1 - - 0.0
180
Multimodular transpeptidase-transglycosylase PBP 1A
1 - - 0.0
186
Golvesin
1 - - 0.0
182
Uncharacterized protein
1 - - 0.0
193
D-alanyl-D-alanine carboxypeptidase family protein
1 - - 0.0
194
Uncharacterized protein
1 - - 0.0
185
Uncharacterized protein
1 - - 0.0
196
Penicillin binding protein 2
1 - - 0.0
190
D-alanyl-D-alanine endopeptidase
1 - - 0.0
179
Uncharacterized protein
1 - - 0.0
191
Uncharacterized protein
1 - - 0.0
188
D-alanyl-D-alanine carboxypeptidase
1 - - 0.0
187
Uncharacterized protein
1 - - 0.0
189
Lpc53E1
1 - - 0.0
178
Conserved protein
1 - - 0.0
181
Penicillin-binding protein 1A
1 - - 0.0
CATH-Gene3D is a Global Biodata Core Resource Learn more...