CATH Classification

Domain Context

CATH Clusters

Superfamily DD-peptidase/beta-lactamase superfamily
Functional Family glutaminase kidney isoform, mitochondrial

Enzyme Information

3.5.1.2
Glutaminase.
based on mapping to UniProt O94925
L-glutamine + H(2)O = L-glutamate + NH(3).

UniProtKB Entries (1)

O94925
GLSK_HUMAN
Homo sapiens
Glutaminase kidney isoform, mitochondrial

PDB Structure

PDB 5UQE
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
The origin and evolution of human glutaminases and their atypical C-terminal ankyrin repeats.
Pasquali, C.C., Islam, Z., Adamoski, D., Ferreira, I.M., Righeto, R.D., Bettini, J., Portugal, R.V., Yue, W.W., Gonzalez, A., Dias, S.M.G., Ambrosio, A.L.B.
J. Biol. Chem.