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CATH Superfamily 3.30.420.10

Ribonuclease H-like superfamily/Ribonuclease H

The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Ribonuclease H-like superfamily/Ribonuclease H
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 8: Ribonuclease H

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 4 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Nucleic acid binding GO:0003676
Interacting selectively and non-covalently with any nucleic acid.
 133 P0A7Y4 (/IDA) P0A7Y4 (/IDA) P0A7Y4 (/IDA) P0A7Y4 (/IDA) P0A7Y4 (/IDA) P0A7Y4 (/IDA) P0A7Y4 (/IDA) P0A7Y4 (/IDA) P0A7Y4 (/IDA) P0A7Y4 (/IDA)
(123 more)
Endonuclease activity GO:0004519
Catalysis of the hydrolysis of ester linkages within nucleic acids by creating internal breaks.
 133 P0A7Y4 (/IDA) P0A7Y4 (/IDA) P0A7Y4 (/IDA) P0A7Y4 (/IDA) P0A7Y4 (/IDA) P0A7Y4 (/IDA) P0A7Y4 (/IDA) P0A7Y4 (/IDA) P0A7Y4 (/IDA) P0A7Y4 (/IDA)
(123 more)
RNA-DNA hybrid ribonuclease activity GO:0004523
Catalysis of the endonucleolytic cleavage of RNA in RNA-DNA hybrids to 5'-phosphomonoesters.
 133 P0A7Y4 (/IDA) P0A7Y4 (/IDA) P0A7Y4 (/IDA) P0A7Y4 (/IDA) P0A7Y4 (/IDA) P0A7Y4 (/IDA) P0A7Y4 (/IDA) P0A7Y4 (/IDA) P0A7Y4 (/IDA) P0A7Y4 (/IDA)
(123 more)
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
 133 P0A7Y4 (/IPI) P0A7Y4 (/IPI) P0A7Y4 (/IPI) P0A7Y4 (/IPI) P0A7Y4 (/IPI) P0A7Y4 (/IPI) P0A7Y4 (/IPI) P0A7Y4 (/IPI) P0A7Y4 (/IPI) P0A7Y4 (/IPI)
(123 more)

There are 1 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
DNA replication, removal of RNA primer GO:0043137
Removal of the Okazaki RNA primer from the lagging strand of replicating DNA, by a combination of the actions of DNA polymerase, DNA helicase and an endonuclease.
 133 P0A7Y4 (/IMP) P0A7Y4 (/IMP) P0A7Y4 (/IMP) P0A7Y4 (/IMP) P0A7Y4 (/IMP) P0A7Y4 (/IMP) P0A7Y4 (/IMP) P0A7Y4 (/IMP) P0A7Y4 (/IMP) P0A7Y4 (/IMP)
(123 more)

There are 0 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.