The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:
"Ribonuclease H-like superfamily/Ribonuclease H
".
FunFam 19: RNA exonuclease NEF-sp
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 3 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
3'-5'-exoribonuclease activity GO:0000175
Catalysis of the sequential cleavage of mononucleotides from a free 3' terminus of an RNA molecule.
|
5 | P53331 (/IMP) P53331 (/IMP) P53331 (/IMP) P53331 (/IMP) P53331 (/IMP) |
|
3'-5' exonuclease activity GO:0008408
Catalysis of the hydrolysis of ester linkages within nucleic acids by removing nucleotide residues from the 3' end.
|
5 | P53331 (/ISS) P53331 (/ISS) P53331 (/ISS) P53331 (/ISS) P53331 (/ISS) |
|
3'-5'-exoribonuclease activity GO:0000175
Catalysis of the sequential cleavage of mononucleotides from a free 3' terminus of an RNA molecule.
|
1 | Q9VRX7 (/IDA) |
There are 7 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) GO:0000467
Exonucleolytic digestion of a pre-rRNA molecule to generate the mature 3'-end of a 5.8S rRNA molecule derived from an originally tricistronic pre-rRNA transcript that contained the Small Subunit (SSU) rRNA, the 5.8S rRNA, and the Large Subunit (LSU) rRNA in that order from 5' to 3' along the primary transcript.
|
5 | P53331 (/IGI) P53331 (/IGI) P53331 (/IGI) P53331 (/IGI) P53331 (/IGI) |
|
Generation of mature 3'-end of 5S rRNA generated by RNA polymerase III GO:0002107
The removal of extra uridine residues from the 3' end of a 5S pre-rRNA generated by transcription by RNA polymerase III to generate the mature 3'-end.
|
5 | P53331 (/IMP) P53331 (/IMP) P53331 (/IMP) P53331 (/IMP) P53331 (/IMP) |
|
TRNA 3'-trailer cleavage, exonucleolytic GO:0034415
Exonucleolytic cleavage of the 3'-end of the pre-tRNA as part of the process of generating the mature 3'-end of the tRNA.
|
5 | P53331 (/IGI) P53331 (/IGI) P53331 (/IGI) P53331 (/IGI) P53331 (/IGI) |
|
TRNA 3'-trailer cleavage, exonucleolytic GO:0034415
Exonucleolytic cleavage of the 3'-end of the pre-tRNA as part of the process of generating the mature 3'-end of the tRNA.
|
5 | P53331 (/IMP) P53331 (/IMP) P53331 (/IMP) P53331 (/IMP) P53331 (/IMP) |
|
U5 snRNA 3'-end processing GO:0034476
Any process involved in forming the mature 3' end of a U5 snRNA molecule.
|
5 | P53331 (/IGI) P53331 (/IGI) P53331 (/IGI) P53331 (/IGI) P53331 (/IGI) |
|
RRNA 3'-end processing GO:0031125
Any process involved in forming the mature 3' end of an rRNA molecule.
|
1 | Q9VRX7 (/IMP) |
|
SnoRNA 3'-end processing GO:0031126
Any process involved in forming the mature 3' end of a snoRNA molecule.
|
1 | Q9VRX7 (/IMP) |
There are 2 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
|
6 | P53331 (/IDA) P53331 (/IDA) P53331 (/IDA) P53331 (/IDA) P53331 (/IDA) Q9VRX7 (/IDA) |
|
Nucleolus GO:0005730
A small, dense body one or more of which are present in the nucleus of eukaryotic cells. It is rich in RNA and protein, is not bounded by a limiting membrane, and is not seen during mitosis. Its prime function is the transcription of the nucleolar DNA into 45S ribosomal-precursor RNA, the processing of this RNA into 5.8S, 18S, and 28S components of ribosomal RNA, and the association of these components with 5S RNA and proteins synthesized outside the nucleolus. This association results in the formation of ribonucleoprotein precursors; these pass into the cytoplasm and mature into the 40S and 60S subunits of the ribosome.
|
1 | Q9VRX7 (/IDA) |