The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Ribonuclease H-like superfamily/Ribonuclease H
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
« Back to all FunFams

FunFam 14: Piwi-like RNA-mediated gene silencing 1

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 16 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
PiRNA binding GO:0034584
Interacting selectively and non-covalently with a piRNA, a Piwi-associated RNA, a 24- to 30-nucleotide RNA derived from repeat or complex DNA sequence elements and processed by a Dicer-independent mechanism.
15 A2CEI6 (/IDA) A8D8P8 (/IDA) O76922 (/IDA) Q7PLK0 (/IDA) Q7Z3Z4 (/IDA) Q7Z3Z4 (/IDA) Q8CDG1 (/IDA) Q8CGT6 (/IDA) Q8TC59 (/IDA) Q8TC59 (/IDA)
(5 more)
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
14 A2CEI6 (/IPI) A8D8P8 (/IPI) A8KBF3 (/IPI) O76922 (/IPI) Q7PLK0 (/IPI) Q8CDG1 (/IPI) Q8CGT6 (/IPI) Q8TC59 (/IPI) Q8TC59 (/IPI) Q8UVX0 (/IPI)
(4 more)
Endoribonuclease activity GO:0004521
Catalysis of the hydrolysis of ester linkages within ribonucleic acid by creating internal breaks.
9 A2CEI6 (/ISS) A6N7Y9 (/ISS) A6P7L8 (/ISS) A8KBF3 (/ISS) Q8TC59 (/ISS) Q8TC59 (/ISS) Q8UVX0 (/ISS) Q96J94 (/ISS) Q96J94 (/ISS)
PiRNA binding GO:0034584
Interacting selectively and non-covalently with a piRNA, a Piwi-associated RNA, a 24- to 30-nucleotide RNA derived from repeat or complex DNA sequence elements and processed by a Dicer-independent mechanism.
8 A6N7Y9 (/ISS) A6P7L8 (/ISS) A8KBF3 (/ISS) Q4G033 (/ISS) Q7Z3Z4 (/ISS) Q7Z3Z4 (/ISS) Q8TC59 (/ISS) Q8TC59 (/ISS)
Single-stranded RNA binding GO:0003727
Interacting selectively and non-covalently with single-stranded RNA.
4 Q1ZXG9 (/ISS) Q54G64 (/ISS) Q7KWS3 (/ISS) Q86HF5 (/ISS)
Endoribonuclease activity GO:0004521
Catalysis of the hydrolysis of ester linkages within ribonucleic acid by creating internal breaks.
4 A8D8P8 (/IMP) Q8CDG1 (/IMP) Q9JMB7 (/IMP) Q9JMB7 (/IMP)
PiRNA binding GO:0034584
Interacting selectively and non-covalently with a piRNA, a Piwi-associated RNA, a 24- to 30-nucleotide RNA derived from repeat or complex DNA sequence elements and processed by a Dicer-independent mechanism.
4 Q8CDG1 (/ISO) Q8CGT6 (/ISO) Q9JMB7 (/ISO) Q9JMB7 (/ISO)
MRNA binding GO:0003729
Interacting selectively and non-covalently with messenger RNA (mRNA), an intermediate molecule between DNA and protein. mRNA includes UTR and coding sequences, but does not contain introns.
3 Q8CDG1 (/IDA) Q9JMB7 (/IDA) Q9JMB7 (/IDA)
MRNA binding GO:0003729
Interacting selectively and non-covalently with messenger RNA (mRNA), an intermediate molecule between DNA and protein. mRNA includes UTR and coding sequences, but does not contain introns.
3 A6N7Y9 (/ISS) Q96J94 (/ISS) Q96J94 (/ISS)
Polysome binding GO:1905538
Interacting selectively and non-covalently with a polysome.
3 Q8CDG1 (/IDA) Q9JMB7 (/IDA) Q9JMB7 (/IDA)
RNA binding GO:0003723
Interacting selectively and non-covalently with an RNA molecule or a portion thereof.
2 O76922 (/IDA) Q7PLK0 (/IDA)
Single-stranded RNA binding GO:0003727
Interacting selectively and non-covalently with single-stranded RNA.
2 Q9JMB7 (/IDA) Q9JMB7 (/IDA)
Protein kinase binding GO:0019901
Interacting selectively and non-covalently with a protein kinase, any enzyme that catalyzes the transfer of a phosphate group, usually from ATP, to a protein substrate.
2 Q9JMB7 (/IPI) Q9JMB7 (/IPI)
MRNA cap binding complex binding GO:0140262
Interacting selectively and non-covalently with a mRNA cap binding complex.
2 Q9JMB7 (/IDA) Q9JMB7 (/IDA)
Magnesium ion binding GO:0000287
Interacting selectively and non-covalently with magnesium (Mg) ions.
1 A8D8P8 (/IDA)
Endoribonuclease activity GO:0004521
Catalysis of the hydrolysis of ester linkages within ribonucleic acid by creating internal breaks.
1 Q8CDG1 (/IDA)

There are 75 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Gene silencing by RNA GO:0031047
Any process in which RNA molecules inactivate expression of target genes.
13 A2CEI6 (/ISS) A6N7Y9 (/ISS) A6P7L8 (/ISS) A8KBF3 (/ISS) Q4G033 (/ISS) Q7Z3Z4 (/ISS) Q7Z3Z4 (/ISS) Q8TC59 (/ISS) Q8TC59 (/ISS) Q96J94 (/ISS)
(3 more)
Spermatogenesis GO:0007283
The process of formation of spermatozoa, including spermatocytogenesis and spermiogenesis.
12 A2CEI6 (/ISS) A6N7Y9 (/ISS) A6P7L8 (/ISS) A8KBF3 (/ISS) Q4G033 (/ISS) Q7Z3Z4 (/ISS) Q7Z3Z4 (/ISS) Q8TC59 (/ISS) Q8TC59 (/ISS) Q8UVX0 (/ISS)
(2 more)
Negative regulation of transposition GO:0010529
Any process that decreases the frequency, rate or extent of transposition. Transposition results in the movement of discrete segments of DNA between nonhomologous sites.
12 A2CEI6 (/ISS) A6N7Y9 (/ISS) A6P7L8 (/ISS) A8KBF3 (/ISS) Q4G033 (/ISS) Q7Z3Z4 (/ISS) Q7Z3Z4 (/ISS) Q8TC59 (/ISS) Q8TC59 (/ISS) Q8UVX0 (/ISS)
(2 more)
PiRNA metabolic process GO:0034587
The chemical reactions and pathways involving piRNAs, Piwi-associated RNAs, a class of 24- to 30-nucleotide RNA derived from repeat or complex DNA sequence elements and processed by a Dicer-independent mechanism.
10 A6N7Y9 (/ISS) A6P7L8 (/ISS) A8KBF3 (/ISS) Q4G033 (/ISS) Q7Z3Z4 (/ISS) Q7Z3Z4 (/ISS) Q8TC59 (/ISS) Q8TC59 (/ISS) Q96J94 (/ISS) Q96J94 (/ISS)
DNA methylation involved in gamete generation GO:0043046
The covalent transfer of a methyl group to C-5 of cytosine that contributes to the establishment of DNA methylation patterns in the gamete.
8 A2CEI6 (/ISS) A6P7L8 (/ISS) A8KBF3 (/ISS) Q4G033 (/ISS) Q7Z3Z4 (/ISS) Q7Z3Z4 (/ISS) Q8TC59 (/ISS) Q8TC59 (/ISS)
Negative regulation of transposition GO:0010529
Any process that decreases the frequency, rate or extent of transposition. Transposition results in the movement of discrete segments of DNA between nonhomologous sites.
6 O76922 (/IMP) Q7PLK0 (/IMP) Q8CDG1 (/IMP) Q8CGT6 (/IMP) Q9JMB7 (/IMP) Q9JMB7 (/IMP)
PiRNA metabolic process GO:0034587
The chemical reactions and pathways involving piRNAs, Piwi-associated RNAs, a class of 24- to 30-nucleotide RNA derived from repeat or complex DNA sequence elements and processed by a Dicer-independent mechanism.
6 A8D8P8 (/IMP) Q8CDG1 (/IMP) Q8CGT6 (/IMP) Q8UVX0 (/IMP) Q9JMB7 (/IMP) Q9JMB7 (/IMP)
RNA 5'-end processing GO:0000966
Any process involved in forming the mature 5' end of an RNA molecule.
5 A2CEI6 (/ISS) A6P7L8 (/ISS) A8KBF3 (/ISS) Q8TC59 (/ISS) Q8TC59 (/ISS)
PiRNA biosynthetic process GO:1990511
The chemical reactions and pathways resulting in the formation of piRNAs, Piwi-associated RNAs, a class of 24- to 30-nucleotide RNA derived from repeat or complex DNA sequence elements and processed by a Dicer-independent mechanism.
5 A2CEI6 (/ISS) A6P7L8 (/ISS) A8KBF3 (/ISS) Q8TC59 (/ISS) Q8TC59 (/ISS)
Spermatogenesis GO:0007283
The process of formation of spermatozoa, including spermatocytogenesis and spermiogenesis.
4 Q8CDG1 (/IMP) Q8CGT6 (/IMP) Q9JMB7 (/IMP) Q9JMB7 (/IMP)
Spermatid development GO:0007286
The process whose specific outcome is the progression of a spermatid over time, from its formation to the mature structure.
4 Q96J94 (/IMP) Q96J94 (/IMP) Q9JMB7 (/IMP) Q9JMB7 (/IMP)
Spermatid development GO:0007286
The process whose specific outcome is the progression of a spermatid over time, from its formation to the mature structure.
4 A6N7Y9 (/ISS) Q8UVX0 (/ISS) Q96J94 (/ISS) Q96J94 (/ISS)
RNA interference GO:0016246
The process in which double-stranded RNAs silence cognate genes. Involves posttranscriptional gene inactivation ('silencing') both of transgenes or dsRNA introduced into a germline, and of the host gene(s) homologous to the transgenes or dsRNA. This silencing is triggered by the introduction of transgenes or double-stranded RNA (dsRNA), and can occur through a specific decrease in the level of mRNA, or by negative regulation of translation, of both host genes and transgenes.
4 Q1ZXG9 (/ISS) Q54G64 (/ISS) Q7KWS3 (/ISS) Q86HF5 (/ISS)
Germ-line stem cell population maintenance GO:0030718
Any process by which an organism or tissue maintains a population of germ-line stem cells.
4 A6P7L8 (/ISS) A8KBF3 (/ISS) Q8TC59 (/ISS) Q8TC59 (/ISS)
Gene silencing by RNA GO:0031047
Any process in which RNA molecules inactivate expression of target genes.
4 O76922 (/IMP) Q8CDG1 (/IMP) Q8CGT6 (/IMP) Q8UVX0 (/IMP)
PiRNA metabolic process GO:0034587
The chemical reactions and pathways involving piRNAs, Piwi-associated RNAs, a class of 24- to 30-nucleotide RNA derived from repeat or complex DNA sequence elements and processed by a Dicer-independent mechanism.
4 A2CEI6 (/IDA) Q8CDG1 (/IDA) Q8CGT6 (/IDA) Q8UVX0 (/IDA)
Spermatogenesis, exchange of chromosomal proteins GO:0035093
The replacement of somatic histones within sperm chromatin with sperm-specific histones or protamines with unique DNA-binding properties, resulting in condensation of the sperm chromatin.
4 A6N7Y9 (/ISS) Q8UVX0 (/ISS) Q96J94 (/ISS) Q96J94 (/ISS)
Negative regulation of circadian rhythm GO:0042754
Any process that stops, prevents, or reduces the frequency, rate or extent of a circadian rhythm behavior.
3 Q8CDG1 (/IMP) Q8TC59 (/IMP) Q8TC59 (/IMP)
Regulation of translation GO:0006417
Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of proteins by the translation of mRNA or circRNA.
2 A6N7Y9 (/ISS) Q8UVX0 (/ISS)
Regulation of translation GO:0006417
Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of proteins by the translation of mRNA or circRNA.
2 Q9JMB7 (/NAS) Q9JMB7 (/NAS)
Gamete generation GO:0007276
The generation and maintenance of gametes in a multicellular organism. A gamete is a haploid reproductive cell.
2 A2CEI6 (/IMP) Q8UVX0 (/IMP)
Gamete generation GO:0007276
The generation and maintenance of gametes in a multicellular organism. A gamete is a haploid reproductive cell.
2 A6P7L8 (/ISS) A8KBF3 (/ISS)
Spermatogenesis GO:0007283
The process of formation of spermatozoa, including spermatocytogenesis and spermiogenesis.
2 Q9JMB7 (/IDA) Q9JMB7 (/IDA)
Spermatid development GO:0007286
The process whose specific outcome is the progression of a spermatid over time, from its formation to the mature structure.
2 Q9JMB7 (/ISO) Q9JMB7 (/ISO)
Epithelial structure maintenance GO:0010669
A tissue homeostatic process required for the maintenance of epithelial structure.
2 Q7Z3Z4 (/IMP) Q7Z3Z4 (/IMP)
Epithelial structure maintenance GO:0010669
A tissue homeostatic process required for the maintenance of epithelial structure.
2 Q4G033 (/ISS) Q8CGT6 (/ISS)
Germ-line stem cell population maintenance GO:0030718
Any process by which an organism or tissue maintains a population of germ-line stem cells.
2 A2CEI6 (/IMP) Q8CDG1 (/IMP)
Spermatogenesis, exchange of chromosomal proteins GO:0035093
The replacement of somatic histones within sperm chromatin with sperm-specific histones or protamines with unique DNA-binding properties, resulting in condensation of the sperm chromatin.
2 Q9JMB7 (/IMP) Q9JMB7 (/IMP)
DNA methylation involved in gamete generation GO:0043046
The covalent transfer of a methyl group to C-5 of cytosine that contributes to the establishment of DNA methylation patterns in the gamete.
2 Q8CDG1 (/IMP) Q8CGT6 (/IMP)
Positive regulation of translation GO:0045727
Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of proteins by the translation of mRNA or circRNA.
2 Q8TC59 (/ISS) Q8TC59 (/ISS)
Oogenesis GO:0048477
The complete process of formation and maturation of an ovum or female gamete from a primordial female germ cell. Examples of this process are found in Mus musculus and Drosophila melanogaster.
2 Q8TC59 (/ISS) Q8TC59 (/ISS)
Meiotic cell cycle GO:0051321
Progression through the phases of the meiotic cell cycle, in which canonically a cell replicates to produce four offspring with half the chromosomal content of the progenitor cell via two nuclear divisions.
2 A6P7L8 (/ISS) A8KBF3 (/ISS)
Positive regulation of nuclear-transcribed mRNA poly(A) tail shortening GO:0060213
Any process that increases the frequency, rate or extent of poly(A) tail shortening of a nuclear-transcribed mRNA. Poly(A) tail shortening is the decrease in length of the poly(A) tail of an mRNA from full length to an oligo(A) length.
2 O76922 (/IMP) Q7PLK0 (/IMP)
MRNA splicing, via spliceosome GO:0000398
The joining together of exons from one or more primary transcripts of messenger RNA (mRNA) and the excision of intron sequences, via a spliceosomal mechanism, so that mRNA consisting only of the joined exons is produced.
1 O76922 (/IC)
RNA 5'-end processing GO:0000966
Any process involved in forming the mature 5' end of an RNA molecule.
1 Q8CDG1 (/IDA)
Oocyte maturation GO:0001556
A developmental process, independent of morphogenetic (shape) change, that is required for an oocyte to attain its fully functional state. Oocyte maturation commences after reinitiation of meiosis commonly starting with germinal vesicle breakdown, and continues up to the second meiotic arrest prior to fertilization.
1 O76922 (/IMP)
Chromatin silencing GO:0006342
Repression of transcription by altering the structure of chromatin, e.g. by conversion of large regions of DNA into an inaccessible state often called heterochromatin.
1 O76922 (/IMP)
Regulation of translational initiation GO:0006446
Any process that modulates the frequency, rate or extent of translational initiation.
1 O76922 (/ISS)
Mitotic chromosome condensation GO:0007076
The cell cycle process in which chromatin structure is compacted prior to and during mitosis in eukaryotic cells.
1 O76922 (/IMP)
Pole cell formation GO:0007279
Formation of a small group of cells (pole cells) at the posterior pole of the insect blastula. They are the first cells to cellularize after the arrival of nuclei at the end of the syncytial blastula stage and are the precursors to the insect germ cells.
1 O76922 (/IGI)
Germ cell development GO:0007281
The process whose specific outcome is the progression of an immature germ cell over time, from its formation to the mature structure (gamete). A germ cell is any reproductive cell in a multicellular organism.
1 Q8UVX0 (/IDA)
Germ cell development GO:0007281
The process whose specific outcome is the progression of an immature germ cell over time, from its formation to the mature structure (gamete). A germ cell is any reproductive cell in a multicellular organism.
1 Q8UVX0 (/IMP)
Regulation of pole plasm oskar mRNA localization GO:0007317
Any process that modulates the frequency, rate or extent of the process in which oskar mRNA is transported to, or maintained in, the oocyte pole plasm.
1 O76922 (/IMP)
Pole plasm protein localization GO:0007318
Any process in which a protein is transported to, or maintained in, the oocyte pole plasm. An example of this is found in Drosophila melanogaster.
1 O76922 (/IMP)
Anatomical structure morphogenesis GO:0009653
The process in which anatomical structures are generated and organized. Morphogenesis pertains to the creation of form.
1 Q8UVX0 (/IDA)
Positive regulation of gene expression GO:0010628
Any process that increases the frequency, rate or extent of gene expression. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product or products (proteins or RNA). This includes the production of an RNA transcript as well as any processing to produce a mature RNA product or an mRNA or circRNA (for protein-coding genes) and the translation of that mRNA or circRNA into protein. Protein maturation is included when required to form an active form of a product from an inactive precursor form.
1 A2CEI6 (/IGI)
Epithelial structure maintenance GO:0010669
A tissue homeostatic process required for the maintenance of epithelial structure.
1 Q8CGT6 (/ISO)
Negative regulation of SMAD protein complex assembly GO:0010991
Any process that decreases the rate, frequency, or extent of SMAD protein complex assembly. SMAD protein complex assembly is the aggregation, arrangement and bonding together of a set of components to form a protein complex that contains SMAD proteins.
1 A2CEI6 (/IPI)
RNA interference GO:0016246
The process in which double-stranded RNAs silence cognate genes. Involves posttranscriptional gene inactivation ('silencing') both of transgenes or dsRNA introduced into a germline, and of the host gene(s) homologous to the transgenes or dsRNA. This silencing is triggered by the introduction of transgenes or double-stranded RNA (dsRNA), and can occur through a specific decrease in the level of mRNA, or by negative regulation of translation, of both host genes and transgenes.
1 O76922 (/IMP)
RNA interference GO:0016246
The process in which double-stranded RNAs silence cognate genes. Involves posttranscriptional gene inactivation ('silencing') both of transgenes or dsRNA introduced into a germline, and of the host gene(s) homologous to the transgenes or dsRNA. This silencing is triggered by the introduction of transgenes or double-stranded RNA (dsRNA), and can occur through a specific decrease in the level of mRNA, or by negative regulation of translation, of both host genes and transgenes.
1 O76922 (/TAS)
Targeting of mRNA for destruction involved in RNA interference GO:0030423
The process in which small interfering RNAs target cognate mRNA molecules for degradation.
1 O76922 (/IMP)
Targeting of mRNA for destruction involved in RNA interference GO:0030423
The process in which small interfering RNAs target cognate mRNA molecules for degradation.
1 Q7KWS3 (/ISS)
Oocyte karyosome formation GO:0030717
The chromosome organization process in which meiotic chromosomes in the oocyte nucleus cluster together to form a compact spherical structure called the karyosome.
1 O76922 (/TAS)
Posttranscriptional gene silencing by RNA GO:0035194
Any process of posttranscriptional gene inactivation (silencing) mediated by small RNA molecules that may trigger RNA (often mRNA) degradation or negatively regulate mRNA translation.
1 Q7PLK0 (/IMP)
Segmentation GO:0035282
The regionalization process that divides an organism or part of an organism into a series of semi-repetitive parts, or segments, often arranged along a longitudinal axis.
1 O76922 (/IGI)
Negative regulation of circadian rhythm GO:0042754
Any process that stops, prevents, or reduces the frequency, rate or extent of a circadian rhythm behavior.
1 Q8CDG1 (/ISO)
Positive regulation of innate immune response GO:0045089
Any process that activates or increases the frequency, rate or extent of the innate immune response, the organism's first line of defense against infection.
1 O76922 (/HMP)
Positive regulation of translation GO:0045727
Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of proteins by the translation of mRNA or circRNA.
1 Q8CDG1 (/IMP)
Regulation of oskar mRNA translation GO:0046011
Any process that modulates the frequency, rate or extent of oskar mRNA translation. To ensure the localization of Oskar protein at the posterior pole of the oocyte, translation of oskar mRNA is repressed during its transport to the posterior pole and activated upon localization of the mRNA at the posterior cortex.
1 O76922 (/TAS)
Positive regulation of oskar mRNA translation GO:0046012
Any process that activates or increases the frequency, rate or extent of oskar mRNA translation.
1 O76922 (/NAS)
Positive regulation of oskar mRNA translation GO:0046012
Any process that activates or increases the frequency, rate or extent of oskar mRNA translation.
1 O76922 (/TAS)
Maintenance of pole plasm mRNA location GO:0046594
The process of maintaining mRNA in a specific location in the oocyte pole plasm. An example of this process is found in Drosophila melanogaster.
1 O76922 (/TAS)
Dorsal appendage formation GO:0046843
Establishment of the dorsal filaments, elaborate specializations of the chorion that protrude from the anterior end of the egg and facilitate embryonic respiration.
1 O76922 (/HMP)
Dorsal appendage formation GO:0046843
Establishment of the dorsal filaments, elaborate specializations of the chorion that protrude from the anterior end of the egg and facilitate embryonic respiration.
1 O76922 (/IMP)
Oogenesis GO:0048477
The complete process of formation and maturation of an ovum or female gamete from a primordial female germ cell. Examples of this process are found in Mus musculus and Drosophila melanogaster.
1 O76922 (/HMP)
Oogenesis GO:0048477
The complete process of formation and maturation of an ovum or female gamete from a primordial female germ cell. Examples of this process are found in Mus musculus and Drosophila melanogaster.
1 Q8CDG1 (/IEP)
Oogenesis GO:0048477
The complete process of formation and maturation of an ovum or female gamete from a primordial female germ cell. Examples of this process are found in Mus musculus and Drosophila melanogaster.
1 O76922 (/TAS)
Defense response to Gram-negative bacterium GO:0050829
Reactions triggered in response to the presence of a Gram-negative bacterium that act to protect the cell or organism.
1 O76922 (/HMP)
Meiotic cell cycle GO:0051321
Progression through the phases of the meiotic cell cycle, in which canonically a cell replicates to produce four offspring with half the chromosomal content of the progenitor cell via two nuclear divisions.
1 A2CEI6 (/IMP)
Positive regulation of meiosis I GO:0060903
Any process that increases the rate, frequency, or extent of meiosis I, a cell cycle process comprising the steps by which a cell progresses through the first phase of meiosis, in which cells divide and homologous chromosomes are paired and segregated from each other, producing two daughter cells.
1 Q8CDG1 (/IMP)
Regulation of insulin secretion involved in cellular response to glucose stimulus GO:0061178
Any process that modulates the frequency, rate or extent of the regulated release of insulin that contributes to the response of a cell to glucose.
1 Q4G033 (/IMP)
Regulation of insulin secretion involved in cellular response to glucose stimulus GO:0061178
Any process that modulates the frequency, rate or extent of the regulated release of insulin that contributes to the response of a cell to glucose.
1 Q8CGT6 (/ISO)
Positive regulation of histone H3-K14 acetylation GO:0071442
Any process that activates or increases the frequency, rate or extent of the addition of an acetyl group to histone H3 at position 14 of the histone.
1 Q8CDG1 (/IMP)
PiRNA biosynthetic process GO:1990511
The chemical reactions and pathways resulting in the formation of piRNAs, Piwi-associated RNAs, a class of 24- to 30-nucleotide RNA derived from repeat or complex DNA sequence elements and processed by a Dicer-independent mechanism.
1 Q8CDG1 (/IDA)
Positive regulation of histone H3-K9 acetylation GO:2000617
Any process that activates or increases the frequency, rate or extent of histone H3-K9 acetylation.
1 Q8CDG1 (/IDA)

There are 24 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
13 A2CEI6 (/IDA) O76922 (/IDA) Q7PLK0 (/IDA) Q7Z3Z3 (/IDA) Q7Z3Z4 (/IDA) Q7Z3Z4 (/IDA) Q8CDG1 (/IDA) Q8CGT6 (/IDA) Q8TC59 (/IDA) Q8TC59 (/IDA)
(3 more)
P granule GO:0043186
A small cytoplasmic, non-membranous RNA/protein complex aggregates in the primordial germ cells of many higher eukaryotes.
13 A2CEI6 (/ISS) A6N7Y9 (/ISS) A6P7L8 (/ISS) A8KBF3 (/ISS) Q4G033 (/ISS) Q7Z3Z4 (/ISS) Q7Z3Z4 (/ISS) Q8TC59 (/ISS) Q8TC59 (/ISS) Q96J94 (/ISS)
(3 more)
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
10 A2CEI6 (/IDA) Q7Z3Z3 (/IDA) Q7Z3Z4 (/IDA) Q7Z3Z4 (/IDA) Q8CDG1 (/IDA) Q8CGT6 (/IDA) Q8TC59 (/IDA) Q8TC59 (/IDA) Q9JMB7 (/IDA) Q9JMB7 (/IDA)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
10 A6N7Y9 (/ISS) A6P7L8 (/ISS) A8KBF3 (/ISS) Q4G033 (/ISS) Q7Z3Z4 (/ISS) Q7Z3Z4 (/ISS) Q8TC59 (/ISS) Q8TC59 (/ISS) Q96J94 (/ISS) Q96J94 (/ISS)
P granule GO:0043186
A small cytoplasmic, non-membranous RNA/protein complex aggregates in the primordial germ cells of many higher eukaryotes.
6 A2CEI6 (/IDA) O76922 (/IDA) Q7PLK0 (/IDA) Q8CDG1 (/IDA) Q8CGT6 (/IDA) Q8UVX0 (/IDA)
Pi-body GO:0071546
A P granule that contains the PIWIL2-TDRD1 module, a set of proteins that act in the primary piRNA pathway. The pi-body corresponds to the cementing material between mitochondria found in gonocytes.
5 A2CEI6 (/ISS) A6P7L8 (/ISS) A8KBF3 (/ISS) Q8TC59 (/ISS) Q8TC59 (/ISS)
PET complex GO:1990923
A protein complex that is composed of at least EXD1, TDRD12 and some PIWI protein. The complex is required for MILI slicing-triggered biogenesis and loading of MIWI2 piRNAs
5 A2CEI6 (/ISS) A6P7L8 (/ISS) A8KBF3 (/ISS) Q8TC59 (/ISS) Q8TC59 (/ISS)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
4 Q8CDG1 (/TAS) Q8CGT6 (/TAS) Q9JMB7 (/TAS) Q9JMB7 (/TAS)
Chromatoid body GO:0033391
A ribonucleoprotein complex found in the cytoplasm of male germ cells, composed of exceedingly thin filaments that are consolidated into a compact mass or into dense strands of varying thickness that branch to form an irregular network. Contains mRNAs, miRNAs, and protein components involved in miRNA processing (such as Argonaute proteins and the endonuclease Dicer) and in RNA decay (such as the decapping enzyme DCP1a and GW182).
4 Q8TC59 (/ISS) Q8TC59 (/ISS) Q96J94 (/ISS) Q96J94 (/ISS)
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
3 Q4G033 (/ISS) Q7Z3Z4 (/ISS) Q7Z3Z4 (/ISS)
Chromatoid body GO:0033391
A ribonucleoprotein complex found in the cytoplasm of male germ cells, composed of exceedingly thin filaments that are consolidated into a compact mass or into dense strands of varying thickness that branch to form an irregular network. Contains mRNAs, miRNAs, and protein components involved in miRNA processing (such as Argonaute proteins and the endonuclease Dicer) and in RNA decay (such as the decapping enzyme DCP1a and GW182).
3 Q8CDG1 (/IDA) Q9JMB7 (/IDA) Q9JMB7 (/IDA)
PiP-body GO:0071547
A P granule that contains the PIWIL4-TDRD9 module, a set of proteins that act in the secondary piRNA pathway.
3 Q4G033 (/ISS) Q7Z3Z4 (/ISS) Q7Z3Z4 (/ISS)
Dense body GO:0097433
An electron dense body which may contain granules.
3 Q8CDG1 (/IDA) Q9JMB7 (/IDA) Q9JMB7 (/IDA)
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
2 Q8CDG1 (/ISO) Q8CGT6 (/ISO)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
2 Q8CDG1 (/ISO) Q8CGT6 (/ISO)
PET complex GO:1990923
A protein complex that is composed of at least EXD1, TDRD12 and some PIWI protein. The complex is required for MILI slicing-triggered biogenesis and loading of MIWI2 piRNAs
2 A8D8P8 (/IDA) Q8CDG1 (/IDA)
Nucleoplasm GO:0005654
That part of the nuclear content other than the chromosomes or the nucleolus.
1 Q8CGT6 (/TAS)
Mitochondrion GO:0005739
A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
1 Q7PLK0 (/IDA)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
1 Q7PLK0 (/IDA)
Perinucleolar chromocenter GO:0010370
A chromocenter adjacent to the nucleolus.
1 Q8CDG1 (/IDA)
Precatalytic spliceosome GO:0071011
A spliceosomal complex that is formed by the recruitment of a preassembled U5-containing tri-snRNP to the prespliceosome. Although all 5 snRNPs are present, the precatalytic spliceosome is catalytically inactive. The precatalytic spliceosome includes many proteins in addition to those found in the associated snRNPs.
1 O76922 (/HDA)
Catalytic step 2 spliceosome GO:0071013
A spliceosomal complex that contains three snRNPs, including U5, bound to a splicing intermediate in which the first catalytic cleavage of the 5' splice site has occurred. The precise subunit composition differs significantly from that of the catalytic step 1, or activated, spliceosome, and includes many proteins in addition to those found in the associated snRNPs.
1 O76922 (/HDA)
Pi-body GO:0071546
A P granule that contains the PIWIL2-TDRD1 module, a set of proteins that act in the primary piRNA pathway. The pi-body corresponds to the cementing material between mitochondria found in gonocytes.
1 Q8CDG1 (/IDA)
PiP-body GO:0071547
A P granule that contains the PIWIL4-TDRD9 module, a set of proteins that act in the secondary piRNA pathway.
1 Q8CGT6 (/IDA)