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CATH Superfamily 1.10.565.10

Retinoid X Receptor

The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Retinoid X Receptor
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.

Browse Functional Families

ID Function Family (FunFam) Name Total Sequences Enzyme? Structure? Structural Representative PDB Sites? Alignment Diversity (0-100)
10
Estrogen receptor
1048
3D
 6iarA00 - 91.2
1
Retinoic acid receptor beta isoform
1039
3D
 6fx0A00 - 76.7
2
Retinoic acid receptor RXR-alpha
994
3D
 4j5xD00 - 73.1
4
Androgen receptor variant
867
3D
 2qpyA00 - 91.4
5
Nuclear orphan receptor ROR-beta
802
3D
 5vb7A00 - 83.2
3
Coup transcription factor 2 isoform 1
641
3D
 3cjwA00 - 75.2
6
Thyroid hormone receptor beta 2
577
3D
 4lnxA00 - 74.4
8
Nuclear receptor subfamily 4 group A member 1
564
3D
 6ddaC00 - 89.2
7
Hepatocyte nuclear factor 4 alpha
557
3D
 4iqrF02 - 76.4
17
Peroxisome proliferator-activated receptor gamma
540
3D
 6md4B00 - 77.3
9
estrogen-related receptor gamma isoform X1
521
3D
 1s9qB00 - 77.5
11
Nuclear receptor subfamily 5, group A, member 2
439
3D
 3f7dA00 - 94.2
13
Peroxisome proliferator-activated receptor delta
426
3D
 5hykA00 - 82.4
12
Nuclear receptor subfamily 2 group C member 1
365
3D
 3p0uB00 - 84.3
14
Oxysterols receptor LXR-alpha isoform 1
351
3D
 5i4vE00 - 75.6
18
Bile acid receptor isoform 4
318
3D
 6a60A00 - 67.8
15
Nuclear receptor subfamily 6 group A member 1
231 - - 77.0
16
Nuclear receptor subfamily 1 group D member 2
211
3D
 4n73A00 - 74.3
19
Nuclear receptor subfamily 2 group E member 1
181 - - 79.5
20
Nuclear receptor subfamily 2 group F member 6
178 - - 85.4
21
Vitamin D3 receptor B
136 - - 64.5
22
Nuclear receptor subfamily 2 group E member 3
126
3D
 4logB00 - 76.2
24
Nuclear receptor subfamily 1 group I member 2
115
3D
 6bnsB00 - 81.4
23
Steroid hormone receptor ERR1
95
3D
 3k6pA00 - 31.3
25
Nuclear receptor subfamily 1 group I member 3
84
3D
 1xvpD00 - 77.4
26
Hepatocyte nuclear factor 4
72 - - 91.8
30
Ecdysone receptor
Isoform A
59
3D
 4oztE00 - 74.1
28
Nuclear receptor subfamily 0 group B member 2
57
3D
 4nufA02 - 79.2
27
nuclear receptor subfamily 0 group B member 1
56 - - 70.4
29
Ecdysone-induced protein 75B, isoform B
54 - - 76.3
31
Nuclear receptor subfamily 0 group B member 1
44 - - 83.6
32
Nuclear hormone receptor FTZ-F1
44
3D
 2xhsA00 - 71.1
33
Nuclear receptor subfamily 4 group A member 2
41 - - 22.6
34
Hormone receptor 4, isoform J
37 - - 70.8
35
Nuclear hormone receptor HR96
30 - - 82.0
36
Nuclear hormone receptor FTZ-F1 beta
29 - - 74.2
37
Hormone receptor 3, isoform C
29 - - 13.4
39
Nuclear receptor subfamily 1, group D, member 4b
26 - - 78.4
38
Dissatisfaction, isoform A
26 - - 80.0
41
Nuclear hormone receptor HR78
24 - - 89.8
40
Uncharacterized protein, isoform A
24 - - 17.8
42
Nuclear receptor subfamily 1, group H, member 5
22 - - 75.3
43
Peroxisome proliferator-activated receptor gamma
21 - - 5.0
47
Ultraspiracle, isoform B
21
3D
 1hg4F00 - 63.4
73
Retinoic acid receptor beta
20
3D
 5uanB02 - 39.0
44
Ecdysone-induced protein 78C, isoform D
19 - - 79.7
45
Nuclear Hormone Receptor family
16 - - 89.8
52
Ultraspiracle nuclear receptor
16
3D
 2nxxD00 - 81.2
46
Hormone receptor 51
15 - - 40.9
48
Nuclear hormone receptor family member nhr-35
15 - - 72.0
50
Nuclear hormone receptor family member daf-12
13 - - 14.7
49
Testicular nuclear receptor 2 variant 2
13 - - 34.8
51
Blast:Protein tailless
13 - - 12.5
53
Nuclear Hormone Receptor family
11 - - 81.7
54
Nuclear Hormone Receptor family
11 - - 88.5
55
Nuclear hormone receptor family member nhr-31
10 - - 9.6
56
Nuclear hormone receptor family member nhr-49
10 - - 21.1
57
Retinoid x receptor
9 - - 14.2
58
Thyroid hormone receptor beta
8 - - 32.5
59
Nuclear Hormone Receptor family
8 - - 53.4
60
Nuclear hormone receptor family member nhr-8
7 - - 19.6
62
Nuclear Hormone Receptor family
7 - - 21.6
63
Hormone receptor 83
7 - - 76.3
61
Protein CBR-NHR-14
7 - - 18.8
65
Nuclear hormone receptor family member nhr-91
7 - - 39.2
64
Coup-like 2 transcription factor
7 - - 89.5
69
Protein CBR-NHR-85
6 - - 78.6
67
Putative retinoic acid receptor alpha
6 - - 14.9
68
Nuclear hormone receptor family member nhr-86
6 - - 90.1
70
Nuclear Hormone Receptor family
6 - - 60.7
66
Nuclear Hormone Receptor family
6 - - 18.2
83
Predicted protein
5 - - 73.5
71
Steroid receptor seven-up, isoform A
5 - - 26.1
76
Nuclear hormone receptor family member nhr-67
5 - - 31.4
80
Nuclear Hormone Receptor family
5 - - 12.9
82
Uncharacterized protein
5 - - 84.1
75
Retinoic acid receptor
5 - - 32.2
74
Nuclear hormone receptor family member nhr-25
5 - - 28.5
77
Nuclear hormone receptor family member nhr-153
5 - - 59.0
72
Nuclear hormone receptor family member nhr-3
5 - - 19.5
79
Hepatocyte nuclear factor 4-alpha
5 - - 5.5
81
Nuclear receptor
5 - - 79.3
78
Peroxisome proliferator-activated receptor gamma
5 - - 86.8
90
AGAP000819-PA
4 - - 13.1
92
AGAP001348-PA
4 - - 11.6
88
Nuclear Hormone Receptor family
4 - - 55.2
93
Nuclear Hormone Receptor family
4 - - 68.4
89
Nuclear hormone receptor family member nhr-111
4 - - 52.9
87
Estrogen-related receptor alpha
4 - - 33.3
91
Retinoid x receptor
4 - - 8.7
85
Vitamin D3 receptor
4 - - 30.0
96
Uncharacterized protein
4 - - 58.3
84
Nuclear receptor subfamily 1, group H, member 5
4 - - 6.3
95
COUP transcription factor 2
4 - - 37.7
94
Protein CBG10507
4 - - 38.1
86
Nuclear receptor subfamily 1, group H, member 5
4 - - 42.1
108
Uncharacterized protein
3 - - 77.3
97
Nuclear Hormone Receptor family
3 - - 28.7
99
Nuclear hormone receptor family member nhr-6
3 - - 24.5
101
Nuclear Hormone Receptor family
3 - - 12.4
107
Uncharacterized protein
3 - - 0.0
98
Protein CBR-UNC-55, isoform a
3 - - 23.1
109
Nuclear receptor, putative
3 - - 73.7
100
Steroid hormone receptor family member cnr14
3 - - 73.0
106
Uncharacterized protein
3 - - 68.0
104
Retinoic acid receptor RXR-gamma-A
3 - - 0.0
103
Nuclear receptor 1
3 - - 8.6
102
Nuclear receptor subfamily 5, group A, member 1b
3 - - 4.2
105
Uncharacterized protein
3 - - 41.0
110
Nuclear Hormone Receptor family
2 - - 19.0
131
Nuclear receptor
2 - - 1.5
142
Uncharacterized protein
2 - - 9.4
116
Uncharacterized protein
2 - - 37.0
114
Nuclear Hormone Receptor family
2 - - 24.1
128
Nuclear receptor
2 - - 0.6
139
Nr1h3 protein
2 - - 40.1
137
RAR related orphan receptor C
2 - - 7.2
113
Nuclear Hormone Receptor family
2 - - 22.3
144
Nuclear receptor subfamily 4, group A, member 3
2 - - 34.0
127
Thyroid hormone receptor
2 - - 3.2
138
Uncharacterized protein
2 - - 37.1
129
Nuclear receptor
2 - - 0.0
143
Peroxisome proliferator-activated receptor alpha
2 - - 30.6
140
Predicted protein
2 - - 36.4
112
Uncharacterized protein
2 - - 20.8
121
Nuclear receptor
2 - - 0.0
115
Nuclear Hormone Receptor family
2 - - 26.9
123
Nuclear Hormone Receptor family
2 - - 0.0
118
Steroid hormone receptor 3
2 - - 0.0
124
Tailless ortholog
2 - - 1.6
126
Protein CBG26996
2 - - 3.2
135
RAR related orphan receptor C
2 - - 40.5
132
uncharacterized protein LOC100187213
2 - - 0.0
141
Uncharacterized protein
2 - - 37.9
120
Nuclear receptor subfamily 5, group A, member 1a
2 - - 1.4
125
nuclear receptor isoform X1
2 - - 0.4
136
Uncharacterized protein
2 - - 35.7
130
AGAP012921-PA
2 - - 42.5
111
Nuclear Hormone Receptor family
2 - - 17.0
122
Hepatocyte nuclear factor 4
2 - - 2.9
133
Nuclear receptor
2 - - 1.9
134
Uncharacterized protein
2 - - 0.0
119
Nuclear hormone receptor family member nhr-121
2 - - 1.3
117
Uncharacterized protein
2 - - 35.4
164
Uncharacterized protein
1 - - 0.0
155
Uncharacterized protein
1 - - 0.0
201
Uncharacterized protein
1 - - 0.0
189
RAR-related orphan receptor A
1 - - 0.0
152
Uncharacterized protein
1 - - 0.0
163
Uncharacterized protein
1 - - 0.0
145
Uncharacterized protein
1 - - 0.0
187
Uncharacterized protein
1 - - 0.0
207
Coup transcription factor, putative
1 - - 0.0
160
Uncharacterized protein
1 - - 0.0
198
Androgen receptor a
1 - - 0.0
209
Retinoic acid receptor alpha protein
1 - - 0.0
215
Uncharacterized protein
1 - - 0.0
178
Protein CBR-NHR-221
1 - - 0.0
212
Uncharacterized protein
1 - - 0.0
181
Uncharacterized protein
1 - - 0.0
166
Uncharacterized protein
1 - - 0.0
179
Hepatocyte nuclear factor 4, alpha
1 - - 0.0
208
Uncharacterized protein
1 - - 0.0
197
Uncharacterized protein
1 - - 0.0
162
Uncharacterized protein
1 - - 0.0
216
Uncharacterized protein
1 - - 0.0
153
nuclear receptor isoform X1
1 - - 0.0
199
Coup transcription factor, putative
1 - - 0.0
177
Nuclear receptor subfamily 5, group A, member 1a
1 - - 0.0
210
Estrogen receptor beta
1 - - 0.0
154
Nuclear Hormone Receptor family
1 - - 0.0
165
Nuclear Hormone Receptor family
1 - - 0.0
171
Uncharacterized protein
1 - - 0.0
191
Uncharacterized protein
1 - - 0.0
156
Nuclear Hormone Receptor family
1 - - 0.0
213
Protein CBG13679
1 - - 0.0
214
Uncharacterized protein
1 - - 0.0
150
Protein CBG20720
1 - - 0.0
188
Uncharacterized protein
1 - - 0.0
146
Uncharacterized protein
1 - - 0.0
211
Estrogen receptor
1 - - 0.0
182
Nuclear receptor subfamily 1 group I member 3
1 - - 0.0
193
DAX
1 - - 0.0
159
Nr1d1 protein
1 - - 0.0
157
Nuclear Hormone Receptor family
1 - - 0.0
173
Uncharacterized protein
1 - - 0.0
174
Uncharacterized protein
1 - - 0.0
149
Nuclear hormone receptor family member nhr-115
1 - - 0.0
147
Uncharacterized protein
1 - - 0.0
194
Uncharacterized protein
1 - - 0.0
185
Uncharacterized protein
1 - - 0.0
196
Uncharacterized protein
1 - - 0.0
151
Uncharacterized protein
1 - - 0.0
205
Uncharacterized protein
1 - - 0.0
176
Uncharacterized protein
1 - - 0.0
217
Uncharacterized protein
1 - - 0.0
170
Nuclear receptor subfamily 2, group E, member 3
1 - - 0.0
168
Protein CBG01262
1 - - 0.0
190
Uncharacterized protein
1 - - 0.0
202
Uncharacterized protein
1 - - 0.0
184
Retinoid X receptor
1 - - 0.0
206
PPARalpha-B
1 - - 0.0
195
Uncharacterized protein
1 - - 0.0
218
Uncharacterized protein
1 - - 0.0
175
Uncharacterized protein
1 - - 0.0
172
Uncharacterized protein
1 - - 0.0
169
Uncharacterized protein
1 - - 0.0
167
Uncharacterized protein
1 - - 0.0
200
Retinoic X receptor alpha
1 - - 0.0
192
Predicted protein
1 - - 0.0
183
Nuclear Hormone Receptor family
1 - - 0.0
180
Hepatic nuclear factor 4, beta
1 - - 0.0
203
Uncharacterized protein
1 - - 0.0
158
Retinoid X receptor, putative
1 - - 0.0
161
Uncharacterized protein
1 - - 0.0
204
Uncharacterized protein
1 - - 0.0
148
Nuclear hormone receptor family member nhr-23
1 - - 0.0
186
Uncharacterized protein
1 - - 0.0
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