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1 keywords

CATH Domain 6fx0A00

CATH Classification

Level CATH Code Description
Class 1 Mainly Alpha
Architecture 1.10 Orthogonal Bundle
Topology 1.10.565 Retinoid X Receptor
Homologous Superfamily 1.10.565.10 Retinoid X Receptor

Domain Context

CATH Clusters

Superfamily Retinoid X Receptor
Functional Family Retinoic acid receptor beta isoform

Enzyme Information

UniProtKB Entries (1)

P13631
RARG_HUMAN
Homo sapiens
Retinoic acid receptor gamma

PDB Structure

PDB 6FX0
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Structure-based design of Trifarotene (CD5789), a potent and selective RAR gamma agonist for the treatment of acne.
Thoreau, E., Arlabosse, J.M., Bouix-Peter, C., Chambon, S., Chantalat, L., Daver, S., Dumais, L., Duvert, G., Feret, A., Ouvry, G., Pascau, J., Raffin, C., Rodeville, N., Soulet, C., Tabet, S., Talano, S., Portal, T.
Bioorg. Med. Chem. Lett.
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