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1 keywords

CATH Domain 3s9yD00

CATH Classification

Level CATH Code Description
Class 3 Alpha Beta
Architecture 3.20 Alpha-Beta Barrel
Topology 3.20.20 TIM Barrel
Homologous Superfamily 3.20.20.70 Aldolase class I

Domain Context

CATH Clusters

Superfamily Aldolase class I
Functional Family Orotidine 5'-phosphate decarboxylase

Enzyme Information

UniProtKB Entries (1)

Q8IJH3
Q8IJH3_PLAF7
Plasmodium falciparum 3D7
Orotidine 5'-phosphate decarboxylase

PDB Structure

PDB 3S9Y
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Structure-activity relationships of orotidine-5'-monophosphate decarboxylase inhibitors as anticancer agents.
Bello, A.M., Konforte, D., Poduch, E., Furlonger, C., Wei, L., Liu, Y., Lewis, M., Pai, E.F., Paige, C.J., Kotra, L.P.
J.Med.Chem.
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