CATH Classification
Level | CATH Code | Description |
---|---|---|
3 | Alpha Beta | |
3.30 | 2-Layer Sandwich | |
3.30.420 | Nucleotidyltransferase; domain 5 | |
3.30.420.40 | ATPase, nucleotide binding domain |
Domain Context
CATH Clusters
Superfamily | 3.30.420.40 |
Functional Family | Probable tRNA N6-adenosine threonylcarbamoyltransferase |
Enzyme Information
2.3.1.234 |
N(6)-L-threonylcarbamoyladenine synthase.
based on mapping to UniProt Q58530
L-threonylcarbamoyladenylate + adenine(37) in tRNA = AMP + N(6)-L- threonylcarbamoyladenine(37) in tRNA.
-!- The enzyme is involved in the synthesis of N(6)- threonylcarbamoyladenosine(37) in tRNAs, which is found in tRNAs with the anticodon NNU, i.e. tRNA(Ile), tRNA(Thr), tRNA(Asn), tRNA(Lys), tRNA(Ser) and tRNA(Arg). -!- Formerly EC 2.6.99.4.
|
2.7.11.1 |
Non-specific serine/threonine protein kinase.
based on mapping to UniProt Q58530
ATP + a protein = ADP + a phosphoprotein.
-!- This is a heterogeneous group of serine/threonine protein kinases that do not have an activating compound and are either non-specific or their specificity has not been analyzed to date. -!- Formerly EC 2.7.1.37 and EC 2.7.1.70.
|
UniProtKB Entries (1)
Q58530 |
KAE1B_METJA
Methanocaldococcus jannaschii DSM 2661
Probable bifunctional tRNA threonylcarbamoyladenosine biosynthesis protein
|
PDB Structure
PDB | 2VWB |
External Links | |
Method | X-RAY DIFFRACTION |
Organism | |
Primary Citation |
Structure of the Archaeal Kae1/Bud32 Fusion Protein Mj1130: A Model for the Eukaryotic Ekc/Keops Subcomplex
Embo J.
|