CATH Classification

Domain Context

CATH Clusters

Superfamily 3.40.50.2300
Functional Family Low molecular weight phosphotyrosine protein

Enzyme Information

3.1.3.2
Acid phosphatase.
based on mapping to UniProt Q9D358
A phosphate monoester + H(2)O = an alcohol + phosphate.
-!- Wide specificity. -!- Also catalyzes transphosphorylations.
3.1.3.48
Protein-tyrosine-phosphatase.
based on mapping to UniProt Q9D358
Protein tyrosine phosphate + H(2)O = protein tyrosine + phosphate.
-!- Dephosphorylates O-phosphotyrosine groups in phosphoproteins, such as the products of EC 2.7.10.2.

UniProtKB Entries (1)

Q9D358
PPAC_MOUSE
Mus musculus
Low molecular weight phosphotyrosine protein phosphatase

PDB Structure

PDB 2P4U
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
Structural genomics of protein phosphatases.
Almo, S.C., Bonanno, J.B., Sauder, J.M., Emtage, S., Dilorenzo, T.P., Malashkevich, V., Wasserman, S.R., Swaminathan, S., Eswaramoorthy, S., Agarwal, R., Kumaran, D., Madegowda, M., Ragumani, S., Patskovsky, Y., Alvarado, J., Ramagopal, U.A., Faber-Barata, J., Chance, M.R., Sali, A., Fiser, A., Zhang, Z.Y., Lawrence, D.S., Burley, S.K.
J.Struct.Funct.Genom.