This superfamily comprises structural domains with a Rossmann fold found in a variety of proteins and enzymes, including response regulators such as LacI-like transcriptional regulators PMID:7973627
, CheY-type chemotaxis response regulators INTERPRO:IPR011006
, (multi-)sensor (hybrid) histidine kinase response regulators PMID:17005198
, phosphate regulon response regulators (PhoP, PhoB), periplasmic binding proteins (PBPs) such as sugar-binding proteins PMID:17473016
, ABC (ATP-binding cassette) transporters and other solute binding proteins (SBPs) PMID:23606130
, histidine kinases, protein tyrosine phosphatases (kinases) PMID:21871460
This domain can perform several functions such as ligand recognition, sugar binding, DNA binding, protein phosphorylation, chemotaxis, quorum sensing PMID:11823863, signal transduction.
Pfam clan [PfamClan:CL0144]