CATH Classification

Domain Context

CATH Clusters

Superfamily 3.40.1280.10
Functional Family tRNA (guanosine(18)-2'-O)-methyltransferase

Enzyme Information

2.1.1.34
tRNA (guanosine(18)-2'-O)-methyltransferase.
based on mapping to UniProt Q5SM16
S-adenosyl-L-methionine + guanosine(18) in tRNA = S-adenosyl-L- homocysteine + 2'-O-methylguanosine(18) in tRNA.
-!- The enzyme catalyzes the methylation of guanosine(18) in tRNA.

UniProtKB Entries (1)

Q5SM16
TRMH_THET8
Thermus thermophilus HB8
TRNA (guanosine(18)-2'-O)-methyltransferase

PDB Structure

PDB 1V2X
External Links
Method X-RAY DIFFRACTION
Organism Spodoptera
Primary Citation
Deep Knot Structure for Construction of Active Site and Cofactor Binding Site of tRNA Modification Enzyme
Nureki, O., Watanabe, K., Fukai, S., Ishii, R., Endo, Y., Hori, H., Yokoyama, S.
STRUCTURE