CATH Superfamily 2.40.70.10

Browse Functional Families

ID	Function Family (FunFam) Name	Total Sequences	Enzyme?	Structure?	Structural Representative	PDB Sites?	Alignment Diversity (0-100)
22959	Gag-pol fusion polyprotein	9369	EC	3D	1a30A00	-	78.2
23154	Aspartyl protease family protein	7770	EC		-	-	89.5
23181	Aspartyl protease family protein	7687	EC	3D	1t6eX02	-	93.4
23148	Aspartic protease pep1	3874	EC	3D	2qzwA01	-	86.8
22912	Cathepsin D Lysosomal aspartyl protease	3758	EC	3D	1bbsA01	-	92.4
23129	Aspartic protease pep1	2105	EC	3D	1aptE02	-	92.3
11579	Truncated pol polyprotein	1650	EC	3D	2r5pA00	-	99.7
23027	Truncated pol protein	1636	EC	3D	3lzsA00	-	99.7
23085	DNA damage-inducible protein 1	1599		3D	2i1aA00	-	89.2
23189	Putative gag-pol polyprotein	1451	EC	3D	1az5A00	-	97.3
22861	Lysosomal aspartic protease, putative	945	EC	3D	1dp5A02	-	88.2
22817	Beta-site APP-cleaving enzyme 1	823	EC	3D	1fknA02	-	80.0
23002	Cathepsin D A01 family	748	EC	3D	1lyaB00	-	87.2
22859	Beta-site APP-cleaving enzyme 1	703	EC	3D	1fknA01	-	78.5
22885	Pepsinogen 5, group I	575	EC	3D	1flhA02	-	88.9
22892	Pepsinogen 4, group I Pepsinogen A	459	EC	3D	1avfA01	-	81.2
22815	Plasmepsin 1	326	EC	3D	1leeA02	-	45.7
22819	Plasmepsin 1	316	EC	3D	1leeA01	-	26.6
22973	Pepsin B	238	EC	3D	1avfA02	-	83.8
22976	Pregnancy-associated glycoprotein 9	191	EC		-	-	90.1
202	Beta-secretase 2	170	EC	3D	2ewyA01	-	84.0
23050	Candidapepsin-8, putative	142	EC	3D	2qzwA02	-	93.6
23169	Probable aspartic-type endopeptidase CTSD	107	EC		-	-	83.4
2195	K7_Bar1p	105	EC		-	-	2.7
22834	Aspartic protease	93	EC	3D	1uh7A01	-	87.6
2022	Yps1p	88	EC		-	-	1.9
22740	Gene model 131, NCBI	87	EC	3D	4aa9A02	-	74.9
3047	Cathepsin D	79	EC	3D	1lyaA00	-	34.4
22837	Strain CBS138 chromosome M complete sequence	78			-	-	38.4
9253	Retroviral-like aspartic protease 1	77			-	-	39.7
23091	Gag-Pro-Pol polyprotein	63	EC	3D	2b7fA00	-	72.3
22945	Retrotransposon-derived protein PEG10	53			-	-	32.8
23009	Nuclear receptor-interacting protein 2	52			-	-	62.9
22963	Retrotransposon-like protein 1	45			-	-	45.2
452	Yps7p	44			-	-	9.6
7	Yps7p	43			-	-	6.8
1847	Plasmepsin 4	41			-	-	0.0
11104	Putative aspartyl protease	41		3D	5c9dA00	-	19.5
1328	Aspartic proteinase MKC7	38	EC		-	-	3.0
9427	Plasmepsin 4	36			-	-	0.0
22946	Probable aspartic-type endopeptidase OPSB	35			-	-	58.1
22969	Alpha-L-glutamate ligase, RimK family	35			-	-	74.8
23184	Putative enzymatic polyprotein	28	EC		-	-	98.0
1852	Aspartic proteinase yapsin-6	25			-	-	2.6
899	Candidapepsin-7	20	EC		-	-	4.6
6668	Uncharacterized protein	17			-	-	9.3
8546	Gag and reverse transcriptase polyprotein	16	EC	3D	1mvpA00	-	3.7
3342	Aspartyl protease family protein	14			-	-	25.9
23015	Protease	13		3D	1nsoA00	-	31.6
22835	Pol polyprotein	12	EC	3D	1b11A00	-	18.0
23019	Probable aspartic-type endopeptidase CTSD	12			-	-	40.8
2291	Aspartyl protease, putative	12	EC		-	-	9.1
653	Uncharacterized protein	10			-	-	0.6
8740	Conserved Plasmodium protein	9			-	-	0.0
591	Acid protease	9			-	-	0.0
3530	Uncharacterized protein	9			-	-	6.3
1419	Basic 7S globulin 2	9		3D	3aupA02	-	0.0
5868	Aspartyl protease family protein	8			-	-	25.8
3060	Basic 7S globulin 2	8			-	-	4.8
3113	Candidapepsin	7	EC		-	-	0.7
3595	Aspartic protease 6	7			-	-	21.6
23077	Pro-Pol polyprotein	7	EC	3D	2jysA00	-	48.3
10112	Gag-pro-pol polyprotein	6			-	-	10.0
4268	Uncharacterized protein	6			-	-	0.8
10692	Gag-Pro-Pol polyprotein	5	EC		-	-	7.6
7283	Aspartic protease 6	5			-	-	9.3
20363	Transposon Ty3-I Gag-Pol polyprotein	5	EC		-	-	1.2
23047	Aspartyl protease-like protein	4			-	-	18.6
3802	Acid extracellular protease	4			-	-	0.0
5224	Acid extracellular protease	4			-	-	0.0
21297	Probable aspartic-type endopeptidase AFUA_3G01220	4			-	-	0.7
1964	Probable aspartic-type endopeptidase CTSD	4			-	-	4.8
6884	GD19153	4			-	-	10.7
7342	GE17615	4			-	-	7.1
5338	Aspartic protease 3	3			-	-	12.6
4496	Aspartyl protease family protein	3			-	-	1.7
7489	Uncharacterized protein	3			-	-	0.0
11692	Pol polyprotein	3			-	-	7.6
10871	YOR192C-B-like protein	3			-	-	8.2
1214	Aspartic protease	2			-	-	0.0
1139	Preprosilpepsin 2	2		3D	1b5fA00	-	0.0
22766	Mucorpepsin	2	EC	3D	1mppA01	-	0.7
3833	Pregnancy-associated glycoprotein 1	2			-	-	0.8
984	Aspartic endopeptidase AP1	2			-	-	0.0
23163	Aspartic proteinase yapsin-1	2			-	-	35.9
3834	IP19142p	2			-	-	4.7
23043	Retrovirus-related Pol polyprotein from transposon 297	2	EC		-	-	36.6
22750	Mucorpepsin	2	EC		-	-	19.3
12036	Retrovirus-related Pol polyprotein from transposon gypsy	2	EC		-	-	0.0
5120	IP19142p	2			-	-	0.7
10872	Gag-Pol polyprotein	1	EC		-	-	0.0
22723	Cardosin-G	1			-	-	0.0
3489	Aspartic proteinase yapsin-1	1			-	-	0.0
8953	Retrovirus-related Pol polyprotein from transposon 412	1	EC		-	-	0.0
19955	Uncharacterized protein K02A2.6	1			-	-	0.0
13392	Putative Polyprotein CP	1			-	-	0.0
3694	Polyporopepsin	1	EC		-	-	0.0
23092	Gastricsin	1			-	-
21162	Gastricsin	1			-	-	0.0
9231	Similar to aspartic proteinase	1			-	-	0.0
23066	Probable vacuolar protease A	1			-	-	0.0
10234	Polyprotein P3	1	EC		-	-	0.0
8422	Aspartyl protease family protein	1			-	-	0.0
5092	Polyporopepsin	1	EC		-	-	0.0
10536	Putative transmembrane signal peptide protein	1			-	-	0.0
8431	Polyprotein P3	1	EC		-	-	0.0
1487	Aspartic proteinase sxa1	1			-	-	0.0
3325	Acid protease	1			-	-	0.0

Network disruptions

CATH Superfamily 2.40.70.10

Acid Proteases

Functional Families

Browse Functional Families