The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Jelly Rolls
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.

Browse Functional Families

ID Function Family (FunFam) Name Total Sequences Enzyme? Structure? Structural Representative PDB Sites? Alignment Diversity (0-100)
1
1193
3D
4r8hB01 - 79.5
3
985
3D
3mzhB01 - 97.9
2
968 - - 91.7
4
869
3D
5e44A01 - 92.6
6
649
3D
5kjzA00 - 91.9
5
648
3D
2eteB00 - 96.0
7
638
3D
3u0zB02 - 72.7
9
574
3D
4lloG00 - 74.0
8
GEF
569 - - 25.6
10
565 - - 92.5
11
526 - - 80.6
12
506 - - 96.1
13
465
3D
4dinB01 - 76.6
14
Eag-related
418
3D
3ukvC02 - 76.0
15
401
3D
4mh0E02 - 49.0
16
380
3D
2oyzA00 - 91.0
17
370
3D
4x6qB01 - 87.3
18
353
3D
1xruB02 - 80.6
19
321
3D
2d93A00 - 44.7
20
304 - - 89.4
21
297
3D
1tq5A02 - 57.6
22
293 - - 84.2
23
287
3D
5nw7A02 - 85.6
24
262
3D
1wgpA01 - 79.8
25
254 - - 97.3
26
244 - - 65.1
27
236
3D
4jvaA02 - 73.2
28
221 - - 24.6
30
215
3D
5zvxA02 - 96.8
29
214 - - 20.1
31
191
3D
4qgnA00 - 83.9
35
184
3D
4z07E00 - 81.5
45
181
3D
2q4sA00 - 82.5
37
179
3D
5jd7A00 - 68.1
32
178 - - 93.3
33
176
3D
2vpvB00 - 98.9
34
171 - - 90.9
36
167 - - 59.3
42
157
3D
5opcA01 - 90.1
38
141
3D
6bq8A00 - 88.3
39
127
3D
3of1A01 - 94.0
43
124
3D
5c8wF00 - 81.5
40
121 - - 63.9
73
121
3D
1ud1C02 - 97.3
41
120 - - 9.9
44
116 - - 95.9
51
112
3D
1dztB00 - 73.3
46
112 - - 73.0
47
108 - - 94.0
48
106 - - 72.7
49
104 - - 14.7
50
103 - - 3.4
54
100
3D
3la7B01 - 47.2
52
99
3D
4f7zA01 - 31.3
53
96 - - 68.7
56
93
3D
4qgmA00 - 83.2
55
92 - - 83.2
57
92
3D
4d7tB02 - 98.2
58
86 - - 28.1
59
85 - - 87.3
62
84 - - 83.6
61
84 - - 64.5
60
84 - - 72.2
63
80 - - 61.8
64
77 - - 88.4
65
71 - - 11.4
68
69
3D
5e16A00 - 95.6
66
69 - - 9.7
67
68 - - 93.4
69
67 - - 47.6
70
66 - - 74.7
71
65 - - 6.4
72
65 - - 84.7
81
63
3D
6h1iA01 - 72.2
77
61
3D
5tkqA00 - 90.4
74
60 - - 99.0
80
60
3D
1lrhD00 - 74.3
75
59 - - 31.3
76
58 - - 25.9
78
54 - - 78.8
79
53 - - 83.0
137
S
52
3D
4e2sP00 - 41.5
82
50 - - 12.1
84
S
49
3D
1rc6B00 - 8.8
83
49 - - 95.3
124
48
3D
1ud1C01 - 92.0
85
47 - - 11.5
162
47
3D
1caxF00 - 80.1
86
47 - - 84.7
87
46 - - 0.0
88
46 - - 53.1
89
45 - - 95.2
91
45
3D
4ofgA00 - 24.4
90
44 - - 73.1
93
44
3D
1zvfB01 - 80.3
92
43 - - 24.2
94
42 - - 17.9
95
41 - - 2.6
96
40 - - 38.8
100
40
3D
3iwzD01 - 7.9
181
39
3D
1uikC01 - 73.9
98
38 - - 86.7
212
38
3D
5x6eN01 - 0.0
97
38 - - 46.7
99
37 - - 92.8
382
S
36
3D
4j1xC02 - 48.8
101
36 - - 7.3
102
32 - - 70.3
104
32 - - 77.5
103
32 - - 6.7
105
32 - - 50.7
106
30 - - 15.1
113
27
3D
2qvsB02 - 39.4
107
27 - - 88.5
108
27 - - 80.3
118
26
3D
3of1A02 - 88.1
109
26 - - 85.3
110
26 - - 9.7
112
26 - - 18.0
111
26 - - 88.7
129
25
3D
4i2oB01 - 76.1
116
25 - - 9.5
114
25 - - 12.4
115
25 - - 13.7
117
25 - - 45.6
139
24
3D
3h7yB02 - 9.3
119
24 - - 22.5
120
24 - - 82.3
122
24 - - 90.6
121
24 - - 2.6
123
24 - - 97.3
127
23 - - 25.5
126
23 - - 3.6
128
23 - - 3.5
130
23 - - 80.0
125
23 - - 23.9
131
22 - - 75.0
132
22 - - 9.0
165
22
3D
2ixcD00 - 56.4
133
22 - - 41.0
135
21 - - 71.8
134
21 - - 5.3
136
20 - - 63.2
138
20 - - 16.0
142
putative
20 - - 79.7
140
20 - - 8.4
141
20 - - 86.2
145
19 - - 73.4
144
19 - - 45.3
143
19 - - 2.0
157
19
3D
2zcwA01 - 77.8
156
19
3D
5kbfB01 - 2.8
146
19 - - 73.7
148
18 - - 85.7
147
2OG II
18 - - 65.6
153
Crp/Fnr family
17 - - 14.2
152
17 - - 17.2
151
17 - - 15.5
150
17 - - 88.8
155
17 - - 7.2
154
17 - - 81.4
158
17 - - 5.6
149
17 - - 72.1
160
16 - - 0.0
161
16 - - 0.0
163
16 - - 9.4
159
16 - - 34.1
164
16 - - 23.5
168
15 - - 27.7
171
15 - - 17.4
170
15 - - 19.8
167
15 - - 3.9
274
15
3D
3bu7B00 - 90.5
169
Catabolite gene activator
15 - - 16.0
228
15
3D
4avcB01 - 34.9
172
15 - - 36.0
173
15 - - 71.7
166
15 - - 60.4
178
14 - - 12.5
177
14 - - 11.8
176
14 - - 11.9
175
14 - - 19.4
174
14 - - 63.8
180
13 - - 9.6
182
13 - - 1.4
184
13 - - 36.0
183
13 - - 10.6
186
13 - - 27.9
179
13 - - 2.3
185
13 - - 10.3
194
12 - - 16.6
193
12 - - 54.6
189
12 - - 71.1
197
12 - - 71.5
191
12 - - 14.5
187
12 - - 56.8
192
12 - - 88.1
195
12 - - 0.0
188
12 - - 44.2
190
12 - - 0.0
516
12
3D
4tlfD02 - 0.8
196
12 - - 10.1
200
11 - - 11.0
199
11 - - 11.8
198
11 - - 42.7
202
11 - - 6.3
201
11 - - 0.0
203
11 - - 9.8
204
11 - - 0.0
206
10 - - 65.4
220
10 - - 92.4
211
10 - - 32.1
218
10 - - 2.8
205
10 - - 76.8
213
MCD
10 - - 14.8
207
10 - - 83.6
215
10 - - 47.3
208
10 - - 13.2
214
10 - - 39.1
217
10 - - 0.0
284
10
3D
1vp6C00 - 21.7
268
10
3D
2z69C00 - 4.2
209
10 - - 0.0
216
10 - - 79.8
304
10
3D
2xlgA00 - 39.8
210
10 - - 17.5
219
10 - - 0.0
226
9 - - 10.6
234
9 - - 0.0
391
9
3D
1j3rB00 - 8.3
221
9 - - 8.6
235
9 - - 18.2
224
9 - - 46.4
227
9 - - 2.2
232
9 - - 1.6
225
9 - - 77.1
233
9 - - 0.0
230
9 - - 41.8
229
9 - - 7.6
222
9 - - 81.5
231
9 - - 12.4
223
9 - - 7.7
236
8 - - 17.5
244
8 - - 72.4
246
8 - - 88.8
237
8 - - 67.3
251
8 - - 66.1
263
8
3D
1zybA01 - 10.2
250
8 - - 25.6
245
8 - - 38.9
241
8 - - 9.7
249
8 - - 93.8
240
8 - - 5.5
239
8 - - 9.2
243
8 - - 51.4
247
8 - - 17.9
238
8 - - 15.6
253
8 - - 90.2
252
8 - - 67.5
248
8 - - 3.4
242
8 - - 35.4
260
7 - - 0.0
254
7 - - 8.4
265
7 - - 0.0
272
7 - - 0.0
262
7 - - 12.2
256
7 - - 5.5
264
7 - - 0.0
255
7 - - 27.1
267
7 - - 71.0
257
7 - - 0.9
259
7 - - 15.7
409
7
3D
4yarA03 - 12.1
273
7 - - 79.7
270
7 - - 0.0
266
7 - - 0.0
269
7 - - 2.0
261
7 - - 22.5
258
7 - - 10.6
271
7 - - 1.3
285
6 - - 8.6
288
6 - - 12.7
295
6 - - 0.0
300
6 - - 40.9
286
6 - - 18.4
301
6 - - 37.3
296
6 - - 0.0
287
6 - - 7.0
294
6 - - 0.0
275
6 - - 18.4
279
6 - - 12.2
293
6 - - 0.9
278
6 - - 7.6
276
6 - - 21.7
292
6 - - 22.1
291
6 - - 5.8
280
6 - - 5.7
299
6 - - 77.6
281
6 - - 0.9
298
6 - - 21.7
289
6 - - 84.0
282
6 - - 0.0
297
6 - - 0.0
277
6 - - 10.1
290
6 - - 43.0
283
6 - - 86.7
331
5 - - 0.0
325
5 - - 3.9
337
5 - - 53.8
311
5 - - 47.3
324
5 - - 0.0
312
5 - - 70.1
309
5 - - 0.0
308
5 - - 0.0
329
5 - - 1.3
333
5 - - 77.6
323
5 - - 8.2
330
5 - - 6.6
322
5 - - 14.3
310
5 - - 0.0
303
5 - - 14.6
332
5 - - 61.8
316
5 - - 0.0
327
5 - - 1.9
320
5 - - 42.9
314
5 - - 14.7
307
5 - - 14.7
326
5 - - 11.2
335
5 - - 73.8
334
5 - - 50.5
302
5 - - 70.7
315
5 - - 12.5
305
5 - - 62.3
328
5 - - 0.0
317
5 - - 9.4
313
5 - - 22.2
397
5
3D
1o4tB00 - 0.0
321
5 - - 67.6
319
5 - - 46.1
336
5 - - 18.4
306
5 - - 45.5
318
5 - - 35.9
358
4 - - 16.9
378
4 - - 80.6
350
4 - - 12.2
340
4 - - 0.0
348
4 - - 0.0
364
4 - - 8.1
367
4 - - 11.6
351
4 - - 9.3
379
4 - - 78.5
342
4 - - 34.3
341
4 - - 16.8
370
4 - - 8.3
380
4 - - 85.9
381
4 - - 75.0
373
4 - - 6.8
366
4 - - 0.0
349
4 - - 14.4
346
4 - - 2.4
352
4 - - 3.0
369
4 - - 11.8
372
4 - - 1.9
359
4 - - 60.0
360
4 - - 72.4
353
4 - - 7.0
375
4 - - 35.1
354
4 - - 49.5
368
4 - - 5.5
347
4 - - 12.5
374
4 - - 0.0
585
4
3D
1ft9B01 - 0.0
361
4 - - 6.7
355
4 - - 30.6
377
4 - - 72.4
338
4 - - 47.4
363
4 - - 7.0
362
4 - - 0.8
376
4 - - 64.3
587
4
3D
3b02A01 - 1.1
343
4 - - 36.3
371
4 - - 9.4
339
4 - - 6.3
345
4 - - 66.0
344
4 - - 48.8
357
4 - - 10.2
365
4 - - 2.9
356
4 - - 8.4
443
3 - - 69.3
437
3 - - 60.0
431
3 - - 14.0
389
3 - - 78.5
418
3 - - 0.8
388
3 - - 48.2
410
3 - - 3.9
430
3 - - 1.8
415
3 - - 71.5
438
3 - - 20.7
444
3 - - 16.3
417
3S
3 - - 9.0
405
3 - - 8.9
416
3 - - 72.7
392
3 - - 4.4
399
3 - - 0.0
436
3 - - 0.0
386
3 - - 5.4
400
3 - - 2.9
441
3 - - 45.4
413
3 - - 40.6
432
3 - - 4.7
427
3 - - 13.8
426
3 - - 11.9
428
3 - - 8.4
414
3 - - 38.8
394
3 - - 0.0
393
3 - - 0.0
387
3 - - 24.1
425
3 - - 8.3
424
3 - - 11.1
395
3 - - 0.0
434
3 - - 0.0
442
3 - - 60.4
429
3 - - 7.1
412
3 - - 64.1
385
3 - - 12.1
433
3 - - 6.8
440
3 - - 71.1
423
3 - - 0.6
422
3 - - 0.0
402
3 - - 0.0
439
3 - - 41.1
411
3 - - 0.0
384
3 - - 10.8
398
3 - - 0.0
407
3 - - 15.8
435
3 - - 0.0
401
3 - - 0.0
404
3 - - 21.0
420
3 - - 2.5
383
3 - - 43.0
419
3 - - 5.6
406
3 - - 6.0
396
3 - - 7.6
403
3 - - 32.4
421
3S
3 - - 13.4
390
3 - - 7.3
408
3 - - 4.5
559
2 - - 0.0
560
2 - - 4.4
580
2 - - 0.0
512
2 - - 6.0
463
2 - - 8.6
458
2 - - 9.5
517
2 - - 10.3
451
2 - - 0.0
454
2 - - 3.0
578
2 - - 0.0
572
2 - - 0.0
540
2 - - 11.4
527
2 - - 0.0
571
2 - - 0.0
495
2 - - 4.1
548
2 - - 43.0
594
2 - - 37.8
486
2 - - 1.1
509
2 - - 43.1
569
2 - - 0.0
485
2 - - 0.0
523
2 - - 0.9
460
2 - - 43.2
453
2 - - 1.2
586
2 - - 9.8
595
2 - - 36.1
488
2 - - 0.0
447
2 - - 0.0
536
2 - - 8.7
452
2 - - 0.0
579
2 - - 0.0
480
2 - - 10.2
535
2 - - 0.0
508
2 - - 43.8
541
2 - - 0.0
558
2 - - 0.0
507
2 - - 29.6
573
2 - - 39.2
567
2 - - 5.0
506
2 - - 14.1
581
2 - - 0.0
496
2 - - 8.6
456
2 - - 12.2
568
2 - - 0.0
493
2 - - 7.9
445
2 - - 20.2
525
2 - - 9.4
582
2 - - 0.0
534
2 - - 0.0
557
2 - - 3.1
468
2 - - 34.6
475
2 - - 0.0
515
2 - - 0.0
519
2 - - 0.0
590
2 - - 36.1
545
2 - - 31.9
588
2 - - 0.0
446
2 - - 36.0
542
2 - - 30.0
498
2 - - 0.8
483
2 - - 5.1
574
2 - - 0.0
566
2 - - 1.1
526
2 - - 0.0
500
2 - - 0.0
533
2 - - 2.0
556
2 - - 4.4
462
2 - - 20.2
477
2 - - 0.0
514
2 - - 0.0
513
2 - - 7.4
476
2 - - 7.0
510
2 - - 41.2
449
2 - - 0.0
549
2 - - 43.1
469
2 - - 37.4
575
2 - - 0.0
589
2 - - 0.0
501
2 - - 45.2
490
2 - - 0.0
543
2 - - 29.5
461
2 - - 20.9
583
2 - - 2.2
591
2 - - 39.6
539
2 - - 0.0
603
2 - - 43.4
565
2 - - 7.9
520
2 - - 4.4
532
2 - - 1.8
584
2 - - 0.0
492
2 - - 0.0
511
2 - - 12.7
489
2 - - 4.3
471
2 - - 39.8
465
2 - - 30.4
502
2 - - 18.1
479
2 - - 9.6
553
2 - - 25.6
555
2 - - 23.7
538
2 - - 0.0
524
2 - - 9.3
554
2 - - 22.1
552
2 - - 23.1
521
2 - - 10.0
598
2 - - 42.3
602
2 - - 45.2
467
2 - - 16.8
481
2 - - 0.0
474
2 - - 0.0
564
2 - - 7.9
563
2 - - 7.2
503
2 - - 23.3
593
2 - - 40.7
576
2 - - 0.0
484
2 - - 0.0
544
2 - - 26.9
464
2 - - 2.1
562
2 - - 6.3
497
2 - - 0.0
518
2 - - 0.0
472
2 - - 40.4
478
2 - - 0.0
546
2 - - 40.2
537
2 - - 11.3
522
2 - - 0.0
599
2 - - 42.9
601
2 - - 47.0
551
2 - - 20.7
529
2 - - 0.0
504
2 - - 20.0
459
2 - - 22.6
531
2 - - 0.0
596
2 - - 41.8
494
2 - - 6.6
487
2 - - 0.0
577
2 - - 0.0
561
2 - - 0.8
448
2 - - 0.0
455
2 - - 0.7
600
2 - - 41.9
457
2 - - 0.0
550
2 - - 14.5
505
2 - - 22.8
592
2 - - 39.6
547
2 - - 39.8
482
2 - - 0.0
499
2 - - 43.7
530
2 - - 2.0
470
2 - - 38.4
570
2 - - 5.9
466
2 - - 29.0
450
2 - - 8.0
491
2 - - 0.0
473
2 - - 26.1
597
2 - - 41.4
528
2 - - 6.6
737
1 - - 0.0
767
1 - - 0.0
798
1 - - 0.0
805
1 - - 0.0
722
1 - - 0.0
634
1 - - 0.0
695
1 - - 0.0
728
1 - - 0.0
742
1 - - 0.0
675
1 - - 0.0
684
1 - - 0.0
833
1 - - 0.0
825
1 - - 0.0
739
1 - - 0.0
662
1 - - 0.0
783
1 - - 0.0
758
1 - - 0.0
706
1 - - 0.0
789
1 - - 0.0
834
1 - - 0.0
772
1 - - 0.0
627
1 - - 0.0
715
1 - - 0.0
653
1 - - 0.0
716
1 - - 0.0
686
1 - - 0.0
685
1 - - 0.0
778
1 - - 0.0
743
1 - - 0.0
720
1 - - 0.0
723
1 - - 0.0
637
1 - - 0.0
690
1 - - 0.0
752
1 - - 0.0
835
1 - - 0.0
683
1 - - 0.0
765
1 - - 0.0
784
1 - - 0.0
762
1 - - 0.0
638
1 - - 0.0
734
1 - - 0.0
824
1 - - 0.0
661
1 - - 0.0
800
1 - - 0.0
678
1 - - 0.0
605
1 - - 0.0
607
1 - - 0.0
773
1 - - 0.0
813
1 - - 0.0
644
1 - - 0.0
759
1 - - 0.0
694
1 - - 0.0
816
1 - - 0.0
652
1 - - 0.0
791
1 - - 0.0
796
1 - - 0.0
787
1 - - 0.0
775
1 - - 0.0
746
1 - - 0.0
744
1 - - 0.0
633
1 - - 0.0
718
1 - - 0.0
700
1 - - 0.0
672
1 - - 0.0
764
1 - - 0.0
769
1 - - 0.0
803
1 - - 0.0
751
1 - - 0.0
606
1 - - 0.0
724
1 - - 0.0
666
1 - - 0.0
691
1 - - 0.0
677
1 - - 0.0
708
1 - - 0.0
650
1 - - 0.0
710
1 - - 0.0
664
1 - - 0.0
646
1 - - 0.0
756
1 - - 0.0
617
1 - - 0.0
651
1 - - 0.0
629
1 - - 0.0
810
1 - - 0.0
660
1 - - 0.0
806
1 - - 0.0
790
1 - - 0.0
604
1 - - 0.0
717
1 - - 0.0
815
1 - - 0.0
671
1 - - 0.0
632
1 - - 0.0
610
1 - - 0.0
692
1 - - 0.0
663
1 - - 0.0
725
1 - - 0.0
615
1 - - 0.0
797
1 - - 0.0
766
1 - - 0.0
658
1 - - 0.0
659
1 - - 0.0
645
1 - - 0.0
682
1 - - 0.0
635
1 - - 0.0
788
1 - - 0.0
709
1 - - 0.0
614
1 - - 0.0
699
1 - - 0.0
687
1 - - 0.0
818
1 - - 0.0
626
1 - - 0.0
826
1 - - 0.0
782
1 - - 0.0
757
1 - - 0.0
809
1 - - 0.0
745
1 - - 0.0
832
Crp/Fnr family
1 - - 0.0
736
1 - - 0.0
781
1 - - 0.0
828
1 - - 0.0
620
1 - - 0.0
730
1 - - 0.0
611
1 - - 0.0
665
1 - - 0.0
649
1 - - 0.0
689
1 - - 0.0
648
1 - - 0.0
642
1 - - 0.0
812
1 - - 0.0
795
1 - - 0.0
794
1 - - 0.0
727
1 - - 0.0
674
1 - - 0.0
732
1 - - 0.0
811
1 - - 0.0
622
1 - - 0.0
819
1 - - 0.0
776
1 - - 0.0
801
1 - - 0.0
830
1 - - 0.0
754
1 - - 0.0
747
1 - - 0.0
704
1 - - 0.0
681
1 - - 0.0
619
1 - - 0.0
698
1 - - 0.0
621
1 - - 0.0
680
1 - - 0.0
679
1 - - 0.0
831
1 - - 0.0
780
1 - - 0.0
647
1 - - 0.0
786
1 - - 0.0
740
1 - - 0.0
719
1 - - 0.0
612
1 - - 0.0
827
1 - - 0.0
701
1 - - 0.0
820
1 - - 0.0
817
1 - - 0.0
731
1 - - 0.0
668
1 - - 0.0
688
1 - - 0.0
750
1 - - 0.0
657
1 - - 0.0
774
1 - - 0.0
768
1 - - 0.0
693
1 - - 0.0
673
1 - - 0.0
770
1 - - 0.0
641
1 - - 0.0
761
1 - - 0.0
616
1 - - 0.0
640
1 - - 0.0
738
1 - - 0.0
804
1 - - 0.0
623
1 - - 0.0
755
1 - - 0.0
777
1 - - 0.0
628
1 - - 0.0
733
1 - - 0.0
630
1 - - 0.0
748
1 - - 0.0
608
1 - - 0.0
711
1 - - 0.0
705
1 - - 0.0
836
1 - - 0.0
785
1 - - 0.0
609
1 - - 0.0
667
1 - - 0.0
741
1 - - 0.0
714
1 - - 0.0
822
1 - - 0.0
779
1 - - 0.0
753
1 - - 0.0
697
1 - - 0.0
726
1 - - 0.0
707
1 - - 0.0
624
1 - - 0.0
792
1 - - 0.0
823
1 - - 0.0
656
1 - - 0.0
729
1 - - 0.0
771
1 - - 0.0
814
1 - - 0.0
808
1 - - 0.0
760
1 - - 0.0
749
1 - - 0.0
829
1 - - 0.0
735
1 - - 0.0
613
1 - - 0.0
721
1 - - 0.0
669
1 - - 0.0
702
1 - - 0.0
639
1 - - 0.0
636
1 - - 0.0
643
1 - - 0.0
821
1 - - 0.0
696
1 - - 0.0
713
1 - - 0.0
676
1 - - 0.0
670
1 - - 0.0
837
1 - - 0.0
625
1 - - 0.0
631
1 - - 0.0
712
1 - - 0.0
763
1 - - 0.0
793
1 - - 0.0
654
1 - - 0.0
618
1 - - 0.0
655
1 - - 0.0
703
1 - - 0.0
799
1 - - 0.0
802
1 - - 0.0
807
1 - - 0.0