CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
2 | Mainly Beta |
|
2.60 | Sandwich |
|
2.60.120 | Jelly Rolls |
|
2.60.120.10 | Jelly Rolls |
Domain Context
CATH Clusters
| Superfamily | Jelly Rolls |
| Functional Family | 1,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase |
Enzyme Information
| 1.13.11.54 |
Acireductone dioxygenase (Fe(2+)-requiring).
based on mapping to UniProt Q9BV57
1,2-dihydroxy-5-(methylthio)pent-1-en-3-one + O(2) = 4-(methylthio)-2- oxobutanoate + formate.
-!- If Ni(2+) is bound instead of Fe(2+), the reaction catalyzed by EC 1.13.11.53 occurs instead. -!- The enzyme from Klebsiella oxytoca (formerly Klebsiella pneumoniae) ATCC 8724 is involved in the methionine salvage pathway.
|
UniProtKB Entries (1)
| Q9BV57 |
MTND_HUMAN
Homo sapiens
1,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase
|
PDB Structure
| PDB | 4QGN |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
Human acireductone dioxygenase with iron ion and L-methionine in active center
TO BE PUBLISHED
|
