PDB 5v3o

PDB Links
Overview

PDB Information

PDB	5V3O
Method	X-RAY DIFFRACTION
Host Organism	Spodoptera frugiperda
Gene Source	Homo sapiens
Primary Citation	A Cereblon Modulator (CC-220) with Improved Degradation of Ikaros and Aiolos. Matyskiela, M.E., Zhang, W., Man, H.W., Muller, G., Khambatta, G., Baculi, F., Hickman, M., LeBrun, L., Pagarigan, B., Carmel, G., Lu, C.C., Lu, G., Riley, M., Satoh, Y., Schafer, P., Daniel, T.O., Carmichael, J., Cathers, B.E., Chamberlain, P.P. J. Med. Chem.
Header	Ligase
Released	2017-03-07
Resolution	3.200
CATH Insert Date	14 May, 2017

PDB Images (10)

Image of CATH 5v3o

5v3o

PDB 5v3o

Image of CATH 5v3oA

5v3oA

PDB Chain 5v3oA

Image of CATH 5v3oC

5v3oC

PDB Chain 5v3oC

Image of CATH 5v3oA01

5v3oA01

CATH Domain 5v3oA01

Image of CATH 5v3oA02

5v3oA02

CATH Domain 5v3oA02

Image of CATH 5v3oA03

5v3oA03

CATH Domain 5v3oA03

Image of CATH 5v3oA04

5v3oA04

CATH Domain 5v3oA04

Image of CATH 5v3oC01

5v3oC01

CATH Domain 5v3oC01

Image of CATH 5v3oC02

5v3oC02

CATH Domain 5v3oC02

Image of CATH 5v3oC03

5v3oC03

CATH Domain 5v3oC03

PDB Prints

PDB Chains (2)

Chain ID	Date inserted into CATH	CATH Status
A	15 May, 2017	Chopped
C	15 May, 2017	Chopped

CATH Domains (7)

Domain ID	Date inserted into CATH	Superfamily	CATH Status
5v3oA01	16 Feb, 2018	2.130.10.10	Assigned
5v3oA02	16 Feb, 2018	2.130.10.10	Assigned
5v3oA03	16 Feb, 2018	2.130.10.10	Assigned
5v3oA04	16 Feb, 2018	1.10.150.910	Assigned
5v3oC01	01 Dec, 2017	2.170.150.20	Assigned
5v3oC02	01 Dec, 2017	2.30.130.40	Assigned
5v3oC03	01 Dec, 2017	1.20.58.1480	Assigned

UniProtKB Entries (2)

Accession	Gene ID	Taxon	Description
Q16531	DDB1_HUMAN	Homo sapiens	DNA damage-binding protein 1
Q96SW2	CRBN_HUMAN	Homo sapiens	Protein cereblon