CATH Domain 5v3oC03

CATH Classification

Level	CATH Code	Description
	1	Mainly Alpha
	1.20	Up-down Bundle
	1.20.58	Methane Monooxygenase Hydroxylase; Chain G, domain 1
	1.20.58.1480

Domain Context

CATH Clusters

Superfamily	1.20.58.1480
Functional Family	Cereblon, isoform CRA_c

Enzyme Information

UniProtKB Entries (1)

CRBN_HUMAN

Homo sapiens

Protein cereblon

PDB Structure

PDB	5V3O
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	A Cereblon Modulator (CC-220) with Improved Degradation of Ikaros and Aiolos. Matyskiela, M.E., Zhang, W., Man, H.W., Muller, G., Khambatta, G., Baculi, F., Hickman, M., LeBrun, L., Pagarigan, B., Carmel, G., Lu, C.C., Lu, G., Riley, M., Satoh, Y., Schafer, P., Daniel, T.O., Carmichael, J., Cathers, B.E., Chamberlain, P.P. J. Med. Chem.