PDB 5nx1

PDB Links
Overview

PDB Information

PDB	5NX1
Method	X-RAY DIFFRACTION
Host Organism	Trichoplusia ni
Gene Source	Homo sapiens
Primary Citation	A potent, proteolysis-resistant inhibitor of kallikrein-related peptidase 6 (KLK6) for cancer therapy, developed by combinatorial engineering. Sananes, A., Cohen, I., Shahar, A., Hockla, A., De Vita, E., Miller, A.K., Radisky, E.S., Papo, N. J.Biol.Chem.
Header	Hydrolase
Released	2017-05-09
Resolution	1.850
CATH Insert Date	06 Jul, 2018

PDB Images (9)

Image of CATH 5nx1

5nx1

PDB 5nx1

Image of CATH 5nx1A

5nx1A

PDB Chain 5nx1A

Image of CATH 5nx1B

5nx1B

PDB Chain 5nx1B

Image of CATH 5nx1C

5nx1C

PDB Chain 5nx1C

Image of CATH 5nx1D

5nx1D

PDB Chain 5nx1D

Image of CATH 5nx1A01

5nx1A01

CATH Domain 5nx1A01

Image of CATH 5nx1A02

5nx1A02

CATH Domain 5nx1A02

Image of CATH 5nx1C00

5nx1C00

CATH Domain 5nx1C00

Image of CATH 5nx1D00

5nx1D00

CATH Domain 5nx1D00

PDB Prints

PDB Chains (4)

Chain ID	Date inserted into CATH	CATH Status
A	06 Jul, 2018	Chopped
B	06 Jul, 2018	Rejected
C	06 Jul, 2018	Chopped
D	06 Jul, 2018	Chopped

CATH Domains (4)

Domain ID	Date inserted into CATH	Superfamily	CATH Status
5nx1A01	05 Apr, 2019		Holding pen
5nx1A02	05 Apr, 2019	2.40.10.10	Assigned
5nx1C00	05 Apr, 2019	4.10.410.10	Assigned
5nx1D00	05 Apr, 2019	4.10.410.10	Assigned

UniProtKB Entries (4)

Accession	Gene ID	Taxon	Description
Q92876	KLK6_HUMAN	Homo sapiens	Kallikrein-6
P05067	A4_HUMAN	Homo sapiens	Amyloid-beta precursor protein
P05067	A4_HUMAN	Homo sapiens	Amyloid-beta precursor protein
P05067	A4_HUMAN	Homo sapiens	Amyloid-beta precursor protein