CATH Domain 5nx1D00

CATH Classification

Level	CATH Code	Description
	4	Few Secondary Structures
	4.10	Irregular
	4.10.410	Factor Xa Inhibitor
	4.10.410.10	Pancreatic trypsin inhibitor Kunitz domain

Domain Context

CATH Clusters

Superfamily	Pancreatic trypsin inhibitor Kunitz domain
Functional Family

Enzyme Information

UniProtKB Entries (1)

A4_HUMAN

Homo sapiens

Amyloid-beta precursor protein

PDB Structure

PDB	5NX1
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	A potent, proteolysis-resistant inhibitor of kallikrein-related peptidase 6 (KLK6) for cancer therapy, developed by combinatorial engineering. Sananes, A., Cohen, I., Shahar, A., Hockla, A., De Vita, E., Miller, A.K., Radisky, E.S., Papo, N. J.Biol.Chem.