CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
4 | Few Secondary Structures |
|
4.10 | Irregular |
|
4.10.410 | Factor Xa Inhibitor |
|
4.10.410.10 | Pancreatic trypsin inhibitor Kunitz domain |
Domain Context
CATH Clusters
| Superfamily | Pancreatic trypsin inhibitor Kunitz domain |
| Functional Family | Amyloid beta A4 protein |
Enzyme Information
UniProtKB Entries (1)
| P05067 |
A4_HUMAN
Homo sapiens
Amyloid-beta precursor protein
|
PDB Structure
| PDB | 5NX1 |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
A potent, proteolysis-resistant inhibitor of kallikrein-related peptidase 6 (KLK6) for cancer therapy, developed by combinatorial engineering.
J.Biol.Chem.
|