PDB 4xsx

PDB Information

PDB4XSX
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceEscherichia coli (strain K12)
Primary Citation
CBR antimicrobials inhibit RNA polymerase via at least two bridge-helix cap-mediated effects on nucleotide addition.
Bae, B., Nayak, D., Ray, A., Mustaev, A., Landick, R., Darst, S.A.
Proc.Natl.Acad.Sci.USA
HeaderTranscription/Antibiotic
Released2015-01-22
Resolution3.710
CATH Insert Date16 Aug, 2015

PDB Images (29)

PDB Prints

PDB Chains (12)

Chain ID Date inserted into CATH CATH Status
A 17 Aug, 2015 Chopped
B 17 Aug, 2015 Chopped
C 17 Aug, 2015 Holding pen
D 17 Aug, 2015 Holding pen
E 17 Aug, 2015 Chopped
F 17 Aug, 2015 Chopped
G 17 Aug, 2015 Chopped
H 17 Aug, 2015 Chopped
I 17 Aug, 2015 Holding pen
J 17 Aug, 2015 Holding pen
K 17 Aug, 2015 Chopped
L 17 Aug, 2015 Chopped

CATH Domains (16)

Domain ID Date inserted into CATH Superfamily CATH Status
4xsxA01 21 Jul, 2016 3.30.1360.10 Assigned
4xsxA02 21 Jul, 2016 2.170.120.12 Assigned
4xsxB01 21 Jul, 2016 3.30.1360.10 Assigned
4xsxB02 21 Jul, 2016 2.170.120.12 Assigned
4xsxE00 24 Aug, 2015 3.90.940.10 Assigned
4xsxF01 24 Aug, 2015 1.10.601.10 Assigned
4xsxF02 24 Aug, 2015 1.10.10.10 Assigned
4xsxF03 24 Aug, 2015 1.10.10.10 Assigned
4xsxG01 21 Jul, 2016 3.30.1360.10 Assigned
4xsxG02 21 Jul, 2016 2.170.120.12 Assigned
4xsxH01 21 Jul, 2016 3.30.1360.10 Assigned
4xsxH02 21 Jul, 2016 2.170.120.12 Assigned
4xsxK00 24 Aug, 2015 3.90.940.10 Assigned
4xsxL01 24 Aug, 2015 1.10.601.10 Assigned
4xsxL02 24 Aug, 2015 1.10.10.10 Assigned
4xsxL03 24 Aug, 2015 1.10.10.10 Assigned

UniProtKB Entries (12)

Accession Gene ID Taxon Description
A8ARN6 RPOZ_CITK8 Citrobacter koseri ATCC BAA-895 DNA-directed RNA polymerase subunit omega
A7ZSI4 RPOA_ECO24 Escherichia coli O139:H28 str. E24377A DNA-directed RNA polymerase subunit alpha
P00579 RPOD_ECOLI Escherichia coli K-12 RNA polymerase sigma factor RpoD
A7ZSI4 RPOA_ECO24 Escherichia coli O139:H28 str. E24377A DNA-directed RNA polymerase subunit alpha
A8ARN6 RPOZ_CITK8 Citrobacter koseri ATCC BAA-895 DNA-directed RNA polymerase subunit omega
A7ZUK2 RPOC_ECO24 Escherichia coli O139:H28 str. E24377A DNA-directed RNA polymerase subunit beta'
A7ZUK2 RPOC_ECO24 Escherichia coli O139:H28 str. E24377A DNA-directed RNA polymerase subunit beta'
A7ZSI4 RPOA_ECO24 Escherichia coli O139:H28 str. E24377A DNA-directed RNA polymerase subunit alpha
P00579 RPOD_ECOLI Escherichia coli K-12 RNA polymerase sigma factor RpoD
A7ZUK1 RPOB_ECO24 Escherichia coli O139:H28 str. E24377A DNA-directed RNA polymerase subunit beta
A7ZSI4 RPOA_ECO24 Escherichia coli O139:H28 str. E24377A DNA-directed RNA polymerase subunit alpha
A7ZUK1 RPOB_ECO24 Escherichia coli O139:H28 str. E24377A DNA-directed RNA polymerase subunit beta
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