CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
1 | Mainly Alpha |
|
1.10 | Orthogonal Bundle |
|
1.10.10 | Arc Repressor Mutant, subunit A |
|
1.10.10.10 | Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain |
Domain Context
CATH Clusters
| Superfamily | Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain |
| Functional Family | RNA polymerase sigma factor SigA |
Enzyme Information
UniProtKB Entries (3)
| A7ZSI4 |
RPOA_ECO24
Escherichia coli O139:H28 str. E24377A
DNA-directed RNA polymerase subunit alpha
|
| A8ARN6 |
RPOZ_CITK8
Citrobacter koseri ATCC BAA-895
DNA-directed RNA polymerase subunit omega
|
| P00579 |
RPOD_ECOLI
Escherichia coli K-12
RNA polymerase sigma factor RpoD
|
PDB Structure
| PDB | 4XSX |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
CBR antimicrobials inhibit RNA polymerase via at least two bridge-helix cap-mediated effects on nucleotide addition.
Proc.Natl.Acad.Sci.USA
|
