PDB 3f9k

PDB Links
Overview

PDB Information

PDB	3F9K
Method	X-RAY DIFFRACTION
Host Organism	Escherichia coli
Gene Source	Human immunodeficiency virus type 2
Primary Citation	A novel co-crystal structure affords the design of gain-of-function lentiviral integrase mutants in the presence of modified PSIP1/LEDGF/p75 Hare, S., Shun, M.C., Gupta, S.S., Valkov, E., Engelman, A., Cherepanov, P. Plos Pathog.
Header	Viral Protein, Recombination
Released	2008-11-14
Resolution	3.200
CATH Insert Date	22 Jan, 2009

PDB Images (97)

3f9k

PDB 3f9k

3f9ka

PDB Chain 3f9ka

3f9kA

PDB Chain 3f9kA

3f9kB

PDB Chain 3f9kB

3f9kc

PDB Chain 3f9kc

3f9kC

PDB Chain 3f9kC

3f9kd

PDB Chain 3f9kd

3f9ke

PDB Chain 3f9ke

3f9kE

PDB Chain 3f9kE

3f9kF

PDB Chain 3f9kF

3f9kg

PDB Chain 3f9kg

3f9kG

PDB Chain 3f9kG

3f9kh

PDB Chain 3f9kh

3f9ki

PDB Chain 3f9ki

3f9kI

PDB Chain 3f9kI

3f9kJ

PDB Chain 3f9kJ

3f9kk

PDB Chain 3f9kk

3f9kK

PDB Chain 3f9kK

3f9kl

PDB Chain 3f9kl

3f9km

PDB Chain 3f9km

3f9kM

PDB Chain 3f9kM

3f9kN

PDB Chain 3f9kN

3f9ko

PDB Chain 3f9ko

3f9kO

PDB Chain 3f9kO

3f9kp

PDB Chain 3f9kp

3f9kq

PDB Chain 3f9kq

3f9kQ

PDB Chain 3f9kQ

3f9kR

PDB Chain 3f9kR

3f9ks

PDB Chain 3f9ks

3f9kS

PDB Chain 3f9kS

3f9kt

PDB Chain 3f9kt

3f9ku

PDB Chain 3f9ku

3f9kU

PDB Chain 3f9kU

3f9kV

PDB Chain 3f9kV

3f9kW

PDB Chain 3f9kW

3f9kY

PDB Chain 3f9kY

3f9kZ

PDB Chain 3f9kZ

3f9ka00

CATH Domain 3f9ka00

3f9kA01

CATH Domain 3f9kA01

3f9kA02

CATH Domain 3f9kA02

3f9kB01

CATH Domain 3f9kB01

3f9kB02

CATH Domain 3f9kB02

3f9kC00

CATH Domain 3f9kC00

3f9kc01

CATH Domain 3f9kc01

3f9kc02

CATH Domain 3f9kc02

3f9kd01

CATH Domain 3f9kd01

3f9kd02

CATH Domain 3f9kd02

3f9ke00

CATH Domain 3f9ke00

3f9kE01

CATH Domain 3f9kE01

3f9kE02

CATH Domain 3f9kE02

3f9kF01

CATH Domain 3f9kF01

3f9kF02

CATH Domain 3f9kF02

3f9kG00

CATH Domain 3f9kG00

3f9kg01

CATH Domain 3f9kg01

3f9kg02

CATH Domain 3f9kg02

3f9kh01

CATH Domain 3f9kh01

3f9kh02

CATH Domain 3f9kh02

3f9ki00

CATH Domain 3f9ki00

3f9kI01

CATH Domain 3f9kI01

3f9kI02

CATH Domain 3f9kI02

3f9kJ01

CATH Domain 3f9kJ01

3f9kJ02

CATH Domain 3f9kJ02

3f9kK00

CATH Domain 3f9kK00

3f9kk01

CATH Domain 3f9kk01

3f9kk02

CATH Domain 3f9kk02

3f9kl01

CATH Domain 3f9kl01

3f9kl02

CATH Domain 3f9kl02

3f9km00

CATH Domain 3f9km00

3f9kM01

CATH Domain 3f9kM01

3f9kM02

CATH Domain 3f9kM02

3f9kN01

CATH Domain 3f9kN01

3f9kN02

CATH Domain 3f9kN02

3f9kO00

CATH Domain 3f9kO00

3f9ko01

CATH Domain 3f9ko01

3f9ko02

CATH Domain 3f9ko02

3f9kp01

CATH Domain 3f9kp01

3f9kp02

CATH Domain 3f9kp02

3f9kq00

CATH Domain 3f9kq00

3f9kQ01

CATH Domain 3f9kQ01

3f9kQ02

CATH Domain 3f9kQ02

3f9kR01

CATH Domain 3f9kR01

3f9kR02

CATH Domain 3f9kR02

3f9kS00

CATH Domain 3f9kS00

3f9ks01

CATH Domain 3f9ks01

3f9ks02

CATH Domain 3f9ks02

3f9kt01

CATH Domain 3f9kt01

3f9kt02

CATH Domain 3f9kt02

3f9ku00

CATH Domain 3f9ku00

3f9kU01

CATH Domain 3f9kU01

3f9kU02

CATH Domain 3f9kU02

3f9kV01

CATH Domain 3f9kV01

3f9kV02

CATH Domain 3f9kV02

3f9kW00

CATH Domain 3f9kW00

3f9kY01

CATH Domain 3f9kY01

3f9kY02

CATH Domain 3f9kY02

3f9kZ01

CATH Domain 3f9kZ01

3f9kZ02

CATH Domain 3f9kZ02

PDB Prints

PDB Chains (36)

Chain ID	Date inserted into CATH	CATH Status
a	22 Jan, 2009	Chopped
A	22 Jan, 2009	Chopped
B	22 Jan, 2009	Chopped
c	22 Jan, 2009	Chopped
C	22 Jan, 2009	Chopped
d	22 Jan, 2009	Chopped
e	22 Jan, 2009	Chopped
E	22 Jan, 2009	Chopped
F	22 Jan, 2009	Chopped
g	22 Jan, 2009	Chopped
G	22 Jan, 2009	Chopped
h	22 Jan, 2009	Chopped
i	22 Jan, 2009	Chopped
I	22 Jan, 2009	Chopped
J	22 Jan, 2009	Chopped
k	22 Jan, 2009	Chopped
K	22 Jan, 2009	Chopped
l	22 Jan, 2009	Chopped
m	22 Jan, 2009	Chopped
M	22 Jan, 2009	Chopped
N	22 Jan, 2009	Chopped
o	22 Jan, 2009	Chopped
O	22 Jan, 2009	Chopped
p	22 Jan, 2009	Chopped
q	22 Jan, 2009	Chopped
Q	22 Jan, 2009	Chopped
R	22 Jan, 2009	Chopped
s	22 Jan, 2009	Chopped
S	22 Jan, 2009	Chopped
t	22 Jan, 2009	Chopped
u	22 Jan, 2009	Chopped
U	22 Jan, 2009	Chopped
V	22 Jan, 2009	Chopped
W	22 Jan, 2009	Chopped
Y	22 Jan, 2009	Chopped
Z	22 Jan, 2009	Chopped

CATH Domains (60)

Domain ID	Date inserted into CATH	Superfamily	CATH Status
3f9ka00	16 Aug, 2010	1.20.930.10	Assigned
3f9kA01	06 Feb, 2013	1.10.10.200	Assigned
3f9kA02	06 Feb, 2013	3.30.420.10	Assigned
3f9kB01	08 Feb, 2013	1.10.10.200	Assigned
3f9kB02	08 Feb, 2013	3.30.420.10	Assigned
3f9kC00	16 Aug, 2010	1.20.930.10	Assigned
3f9kc01	08 Feb, 2013	1.10.10.200	Assigned
3f9kc02	08 Feb, 2013	3.30.420.10	Assigned
3f9kd01	08 Feb, 2013	1.10.10.200	Assigned
3f9kd02	08 Feb, 2013	3.30.420.10	Assigned
3f9ke00	16 Aug, 2010	1.20.930.10	Assigned
3f9kE01	08 Feb, 2013	1.10.10.200	Assigned
3f9kE02	08 Feb, 2013	3.30.420.10	Assigned
3f9kF01	08 Feb, 2013	1.10.10.200	Assigned
3f9kF02	08 Feb, 2013	3.30.420.10	Assigned
3f9kG00	16 Aug, 2010	1.20.930.10	Assigned
3f9kg01	08 Feb, 2013	1.10.10.200	Assigned
3f9kg02	08 Feb, 2013	3.30.420.10	Assigned
3f9kh01	08 Feb, 2013	1.10.10.200	Assigned
3f9kh02	08 Feb, 2013	3.30.420.10	Assigned
3f9ki00	16 Aug, 2010	1.20.930.10	Assigned
3f9kI01	08 Feb, 2013	1.10.10.200	Assigned
3f9kI02	08 Feb, 2013	3.30.420.10	Assigned
3f9kJ01	07 Feb, 2013	1.10.10.200	Assigned
3f9kJ02	07 Feb, 2013	3.30.420.10	Assigned
3f9kK00	16 Aug, 2010	1.20.930.10	Assigned
3f9kk01	08 Feb, 2013	1.10.10.200	Assigned
3f9kk02	08 Feb, 2013	3.30.420.10	Assigned
3f9kl01	08 Feb, 2013	1.10.10.200	Assigned
3f9kl02	08 Feb, 2013	3.30.420.10	Assigned
3f9km00	16 Aug, 2010	1.20.930.10	Assigned
3f9kM01	08 Feb, 2013	1.10.10.200	Assigned
3f9kM02	08 Feb, 2013	3.30.420.10	Assigned
3f9kN01	08 Feb, 2013	1.10.10.200	Assigned
3f9kN02	08 Feb, 2013	3.30.420.10	Assigned
3f9kO00	16 Aug, 2010	1.20.930.10	Assigned
3f9ko01	08 Feb, 2013	1.10.10.200	Assigned
3f9ko02	08 Feb, 2013	3.30.420.10	Assigned
3f9kp01	08 Feb, 2013	1.10.10.200	Assigned
3f9kp02	08 Feb, 2013	3.30.420.10	Assigned
3f9kq00	16 Aug, 2010	1.20.930.10	Assigned
3f9kQ01	08 Feb, 2013	1.10.10.200	Assigned
3f9kQ02	08 Feb, 2013	3.30.420.10	Assigned
3f9kR01	08 Feb, 2013	1.10.10.200	Assigned
3f9kR02	08 Feb, 2013	3.30.420.10	Assigned
3f9kS00	16 Aug, 2010	1.20.930.10	Assigned
3f9ks01	08 Feb, 2013	1.10.10.200	Assigned
3f9ks02	08 Feb, 2013	3.30.420.10	Assigned
3f9kt01	08 Feb, 2013	1.10.10.200	Assigned
3f9kt02	08 Feb, 2013	3.30.420.10	Assigned
3f9ku00	16 Aug, 2010	1.20.930.10	Assigned
3f9kU01	08 Feb, 2013	1.10.10.200	Assigned
3f9kU02	08 Feb, 2013	3.30.420.10	Assigned
3f9kV01	08 Feb, 2013	1.10.10.200	Assigned
3f9kV02	08 Feb, 2013	3.30.420.10	Assigned
3f9kW00	16 Aug, 2010	1.20.930.10	Assigned
3f9kY01	08 Feb, 2013	1.10.10.200	Assigned
3f9kY02	08 Feb, 2013	3.30.420.10	Assigned
3f9kZ01	08 Feb, 2013	1.10.10.200	Assigned
3f9kZ02	08 Feb, 2013	3.30.420.10	Assigned

UniProtKB Entries (36)

Accession	Gene ID	Taxon	Description
O75475	PSIP1_HUMAN	Homo sapiens	PC4 and SFRS1-interacting protein
O75475	PSIP1_HUMAN	Homo sapiens	PC4 and SFRS1-interacting protein
O75475	PSIP1_HUMAN	Homo sapiens	PC4 and SFRS1-interacting protein
O75475	PSIP1_HUMAN	Homo sapiens	PC4 and SFRS1-interacting protein
P04584	POL_HV2RO	Human immunodeficiency virus type 2 (ISOLATE ROD)	Gag-Pol polyprotein
P04584	POL_HV2RO	Human immunodeficiency virus type 2 (ISOLATE ROD)	Gag-Pol polyprotein
O75475	PSIP1_HUMAN	Homo sapiens	PC4 and SFRS1-interacting protein
P04584	POL_HV2RO	Human immunodeficiency virus type 2 (ISOLATE ROD)	Gag-Pol polyprotein
P04584	POL_HV2RO	Human immunodeficiency virus type 2 (ISOLATE ROD)	Gag-Pol polyprotein
P04584	POL_HV2RO	Human immunodeficiency virus type 2 (ISOLATE ROD)	Gag-Pol polyprotein
P04584	POL_HV2RO	Human immunodeficiency virus type 2 (ISOLATE ROD)	Gag-Pol polyprotein
P04584	POL_HV2RO	Human immunodeficiency virus type 2 (ISOLATE ROD)	Gag-Pol polyprotein
P04584	POL_HV2RO	Human immunodeficiency virus type 2 (ISOLATE ROD)	Gag-Pol polyprotein
O75475	PSIP1_HUMAN	Homo sapiens	PC4 and SFRS1-interacting protein
O75475	PSIP1_HUMAN	Homo sapiens	PC4 and SFRS1-interacting protein
O75475	PSIP1_HUMAN	Homo sapiens	PC4 and SFRS1-interacting protein
O75475	PSIP1_HUMAN	Homo sapiens	PC4 and SFRS1-interacting protein
P04584	POL_HV2RO	Human immunodeficiency virus type 2 (ISOLATE ROD)	Gag-Pol polyprotein
P04584	POL_HV2RO	Human immunodeficiency virus type 2 (ISOLATE ROD)	Gag-Pol polyprotein
P04584	POL_HV2RO	Human immunodeficiency virus type 2 (ISOLATE ROD)	Gag-Pol polyprotein
P04584	POL_HV2RO	Human immunodeficiency virus type 2 (ISOLATE ROD)	Gag-Pol polyprotein
O75475	PSIP1_HUMAN	Homo sapiens	PC4 and SFRS1-interacting protein
P04584	POL_HV2RO	Human immunodeficiency virus type 2 (ISOLATE ROD)	Gag-Pol polyprotein
P04584	POL_HV2RO	Human immunodeficiency virus type 2 (ISOLATE ROD)	Gag-Pol polyprotein
P04584	POL_HV2RO	Human immunodeficiency virus type 2 (ISOLATE ROD)	Gag-Pol polyprotein
P04584	POL_HV2RO	Human immunodeficiency virus type 2 (ISOLATE ROD)	Gag-Pol polyprotein
P04584	POL_HV2RO	Human immunodeficiency virus type 2 (ISOLATE ROD)	Gag-Pol polyprotein
O75475	PSIP1_HUMAN	Homo sapiens	PC4 and SFRS1-interacting protein
P04584	POL_HV2RO	Human immunodeficiency virus type 2 (ISOLATE ROD)	Gag-Pol polyprotein
O75475	PSIP1_HUMAN	Homo sapiens	PC4 and SFRS1-interacting protein
P04584	POL_HV2RO	Human immunodeficiency virus type 2 (ISOLATE ROD)	Gag-Pol polyprotein
P04584	POL_HV2RO	Human immunodeficiency virus type 2 (ISOLATE ROD)	Gag-Pol polyprotein
P04584	POL_HV2RO	Human immunodeficiency virus type 2 (ISOLATE ROD)	Gag-Pol polyprotein
P04584	POL_HV2RO	Human immunodeficiency virus type 2 (ISOLATE ROD)	Gag-Pol polyprotein
P04584	POL_HV2RO	Human immunodeficiency virus type 2 (ISOLATE ROD)	Gag-Pol polyprotein
P04584	POL_HV2RO	Human immunodeficiency virus type 2 (ISOLATE ROD)	Gag-Pol polyprotein