The name of this superfamily has been modified since the most recent official CATH+ release (v4_4_0). At the point of the last release, this superfamily was: waiting to be named.

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 1: Zinc finger CCCH domain-containing protein 14

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 4 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
RNA binding GO:0003723
Interacting selectively and non-covalently with an RNA molecule or a portion thereof.
1 Q6PJT7 (/HDA)
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
1 Q6PJT7 (/IPI)
Poly(A) binding GO:0008143
Interacting selectively and non-covalently with a sequence of adenylyl residues in an RNA molecule, such as the poly(A) tail, a sequence of adenylyl residues at the 3' end of eukaryotic mRNA.
1 Q9V3H9 (/IDA)
Sequence-specific mRNA binding GO:1990825
Interacting selectively and non-covalently with messenger RNA (mRNA) of a specific nucleotide composition or a specific sequence motif.
1 Q9V3H9 (/IDA)

There are 2 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Negative regulation of gene expression GO:0010629
Any process that decreases the frequency, rate or extent of gene expression. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product or products (proteins or RNA). This includes the production of an RNA transcript as well as any processing to produce a mature RNA product or an mRNA or circRNA (for protein-coding genes) and the translation of that mRNA or circRNA into protein. Protein maturation is included when required to form an active form of a product from an inactive precursor form.
1 Q9V3H9 (/IMP)
Negative regulation of mRNA polyadenylation GO:1900364
Any process that stops, prevents or reduces the frequency, rate or extent of mRNA polyadenylation.
1 Q9V3H9 (/IMP)

There are 17 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
10 Q08AZ1 (/ISS) Q08AZ1 (/ISS) Q3ZC82 (/ISS) Q4R6F6 (/ISS) Q4R6F6 (/ISS) Q4R6F6 (/ISS) Q5F3Z9 (/ISS) Q5TYQ8 (/ISS) Q7TMD5 (/ISS) Q8BJ05 (/ISS)
Nuclear speck GO:0016607
A discrete extra-nucleolar subnuclear domain, 20-50 in number, in which splicing factors are seen to be localized by immunofluorescence microscopy.
9 G3V256 (/IDA) G3V256 (/IDA) G3V256 (/IDA) G3V5I6 (/IDA) G3V5I6 (/IDA) H0YJA2 (/IDA) Q6PJT7 (/IDA) Q7TMD5 (/IDA) Q8BJ05 (/IDA)
Nuclear speck GO:0016607
A discrete extra-nucleolar subnuclear domain, 20-50 in number, in which splicing factors are seen to be localized by immunofluorescence microscopy.
8 Q08AZ1 (/ISS) Q08AZ1 (/ISS) Q3ZC82 (/ISS) Q4R6F6 (/ISS) Q4R6F6 (/ISS) Q4R6F6 (/ISS) Q5F3Z9 (/ISS) Q5TYQ8 (/ISS)
Nucleolus GO:0005730
A small, dense body one or more of which are present in the nucleus of eukaryotic cells. It is rich in RNA and protein, is not bounded by a limiting membrane, and is not seen during mitosis. Its prime function is the transcription of the nucleolar DNA into 45S ribosomal-precursor RNA, the processing of this RNA into 5.8S, 18S, and 28S components of ribosomal RNA, and the association of these components with 5S RNA and proteins synthesized outside the nucleolus. This association results in the formation of ribonucleoprotein precursors; these pass into the cytoplasm and mature into the 40S and 60S subunits of the ribosome.
7 G3V256 (/IDA) G3V256 (/IDA) G3V256 (/IDA) G3V5I6 (/IDA) G3V5I6 (/IDA) H0YJA2 (/IDA) Q6PJT7 (/IDA)
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
2 Q6PJT7 (/IDA) Q9V3H9 (/IDA)
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
1 Q8BJ05 (/ISO)
Nucleolus GO:0005730
A small, dense body one or more of which are present in the nucleus of eukaryotic cells. It is rich in RNA and protein, is not bounded by a limiting membrane, and is not seen during mitosis. Its prime function is the transcription of the nucleolar DNA into 45S ribosomal-precursor RNA, the processing of this RNA into 5.8S, 18S, and 28S components of ribosomal RNA, and the association of these components with 5S RNA and proteins synthesized outside the nucleolus. This association results in the formation of ribonucleoprotein precursors; these pass into the cytoplasm and mature into the 40S and 60S subunits of the ribosome.
1 Q8BJ05 (/ISO)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
1 Q8BJ05 (/ISO)
Nuclear speck GO:0016607
A discrete extra-nucleolar subnuclear domain, 20-50 in number, in which splicing factors are seen to be localized by immunofluorescence microscopy.
1 Q8BJ05 (/ISO)
Plasma membrane bounded cell projection cytoplasm GO:0032838
All of the contents of a plasma membrane bounded cell projection, excluding the plasma membrane surrounding the projection.
1 Q9V3H9 (/IDA)
Dendrite cytoplasm GO:0032839
All of the contents of a dendrite, excluding the surrounding plasma membrane.
1 Q6PJT7 (/IDA)
Dendrite cytoplasm GO:0032839
All of the contents of a dendrite, excluding the surrounding plasma membrane.
1 Q8BJ05 (/ISO)
Neuron projection GO:0043005
A prolongation or process extending from a nerve cell, e.g. an axon or dendrite.
1 Q9V3H9 (/IDA)
Axon cytoplasm GO:1904115
Any cytoplasm that is part of a axon.
1 Q6PJT7 (/IDA)
Axon cytoplasm GO:1904115
Any cytoplasm that is part of a axon.
1 Q8BJ05 (/ISO)
Ribonucleoprotein complex GO:1990904
A macromolecular complex containing both protein and RNA molecules.
1 Q6PJT7 (/IDA)
Ribonucleoprotein complex GO:1990904
A macromolecular complex containing both protein and RNA molecules.
1 Q8BJ05 (/ISO)
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