The name of this superfamily has been modified since the most recent official CATH+ release (v4_4_0). At the point of the last release, this superfamily was named:
"Cytosolic phospholipase A2 catalytic domain
".
FunFam 42: Patatin-like phospholipase domain-containing 3
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 8 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
1-acylglycerol-3-phosphate O-acyltransferase activity GO:0003841
Catalysis of the reaction: acyl-CoA + 1-acyl-sn-glycerol-3-phosphate = CoA + 1,2-diacyl-sn-glycerol-3-phosphate.
|
1 | Q9NST1 (/IDA) |
|
Phospholipase A2 activity GO:0004623
Catalysis of the reaction: phosphatidylcholine + H2O = 1-acylglycerophosphocholine + a carboxylate.
|
1 | Q9NST1 (/IDA) |
|
Triglyceride lipase activity GO:0004806
Catalysis of the reaction: triacylglycerol + H2O = diacylglycerol + a carboxylate.
|
1 | Q9NST1 (/IDA) |
|
Lysophosphatidic acid binding GO:0035727
Interacting selectively and non-covalently with lysophosphatidic acid (LPA), a phospholipid derivative that acts as a potent mitogen due to its activation of high-affinity G protein-coupled receptors.
|
1 | Q9NST1 (/IDA) |
|
Long-chain fatty acyl-CoA binding GO:0036042
Interacting selectively and non-covalently with a long-chain fatty acyl-CoA. A long-chain fatty acyl-CoA is any derivative of coenzyme A in which the sulfhydryl group is in a thioester linkage with a long-chain fatty-acyl group. Long-chain fatty-acyl-CoAs have chain lengths of C13 or more.
|
1 | Q9NST1 (/IDA) |
|
Lysophosphatidic acid acyltransferase activity GO:0042171
Catalysis of the transfer of acyl groups from an acyl-CoA to lysophosphatidic acid to form phosphatidic acid.
|
1 | Q9NST1 (/IDA) |
|
Mono-olein transacylation activity GO:0051264
Catalysis of the reaction: mono-olein + mono-olein = diolein + glycerol. Mono-olein, also known as mono-oleoylglycerol, is the monoglyceride formed from oleic acid, 9-octodecenoic acid; diolein is also known as dioleoylglycerol.
|
1 | Q9NST1 (/IDA) |
|
Diolein transacylation activity GO:0051265
Catalysis of the reaction: diolein + mono-olein = triolein + glycerol. Mono-olein, also known as mono-oleoylglycerol, is the monoglyceride formed from oleic acid, 9-octodecenoic acid; diolein is also known as dioleoylglycerol, and triolein as trioleoylglycerol and olein.
|
1 | Q9NST1 (/IDA) |
There are 8 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Long-chain fatty acid metabolic process GO:0001676
The chemical reactions and pathways involving long-chain fatty acids, A long-chain fatty acid is a fatty acid with a chain length between C13 and C22.
|
1 | Q9NST1 (/IDA) |
|
Glycerophospholipid metabolic process GO:0006650
The chemical reactions and pathways involving glycerophospholipids, any derivative of glycerophosphate that contains at least one O-acyl, O-alkyl, or O-alkenyl group attached to the glycerol residue.
|
1 | Q9NST1 (/IDA) |
|
Phosphatidic acid biosynthetic process GO:0006654
The chemical reactions and pathways resulting in the formation of phosphatidic acid, any derivative of glycerol phosphate in which both the remaining hydroxyl groups of the glycerol moiety are esterified with fatty acids.
|
1 | Q9NST1 (/IDA) |
|
Triglyceride biosynthetic process GO:0019432
The chemical reactions and pathways resulting in the formation of a triglyceride, any triester of glycerol.
|
1 | Q9NST1 (/IDA) |
|
Triglyceride catabolic process GO:0019433
The chemical reactions and pathways resulting in the breakdown of a triglyceride, any triester of glycerol.
|
1 | Q9NST1 (/IDA) |
|
Lipid droplet organization GO:0034389
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a lipid particle.
|
1 | Q9NST1 (/IMP) |
|
Triglyceride acyl-chain remodeling GO:0036153
Remodeling the acyl chains of triacylglycerol, through sequential deacylation and re-acylation reactions, to generate triacylglycerol containing different types of fatty acid acyl chains.
|
1 | Q9NST1 (/IDA) |
|
Acylglycerol acyl-chain remodeling GO:0036155
Remodeling the acyl chains of an acylglycerol, through sequential deacylation and re-acylation reactions, to generate an acylglycerol containing different types of fatty acid acyl chains.
|
1 | Q9NST1 (/TAS) |
There are 4 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Endoplasmic reticulum membrane GO:0005789
The lipid bilayer surrounding the endoplasmic reticulum.
|
1 | Q9NST1 (/TAS) |
|
Lipid droplet GO:0005811
An intracellular non-membrane-bounded organelle comprising a matrix of coalesced lipids surrounded by a phospholipid monolayer. May include associated proteins.
|
1 | Q9NST1 (/IDA) |
|
Membrane GO:0016020
A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it.
|
1 | Q9NST1 (/IDA) |
|
Membrane GO:0016020
A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it.
|
1 | Q9NST1 (/ISS) |
