The name of this superfamily has been modified since the most recent official CATH+ release (v4_4_0). At the point of the last release, this superfamily was named:
"Cytosolic phospholipase A2 catalytic domain
".
FunFam 23: Phospholipase A2 group IVC
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 4 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Lysophospholipase activity GO:0004622
Catalysis of the reaction: 2-lysophosphatidylcholine + H2O = glycerophosphocholine + a carboxylate.
|
2 | Q9UP65 (/TAS) Q9UP65 (/TAS) |
|
Phospholipid binding GO:0005543
Interacting selectively and non-covalently with phospholipids, a class of lipids containing phosphoric acid as a mono- or diester.
|
2 | Q9UP65 (/NAS) Q9UP65 (/NAS) |
|
Phospholipase A1 activity GO:0008970
Catalysis of the reaction: phosphatidylcholine + H2O = 2-acylglycerophosphocholine + a carboxylate.
|
2 | Q9UP65 (/TAS) Q9UP65 (/TAS) |
|
Calcium-independent phospholipase A2 activity GO:0047499
Catalysis of the reaction: phosphatidylcholine + H2O = 1-acylglycerophosphocholine + a carboxylate. This reaction does not require Ca2+.
|
2 | Q9UP65 (/IDA) Q9UP65 (/IDA) |
There are 9 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Phospholipid metabolic process GO:0006644
The chemical reactions and pathways involving phospholipids, any lipid containing phosphoric acid as a mono- or diester.
|
2 | Q9UP65 (/TAS) Q9UP65 (/TAS) |
|
Inflammatory response GO:0006954
The immediate defensive reaction (by vertebrate tissue) to infection or injury caused by chemical or physical agents. The process is characterized by local vasodilation, extravasation of plasma into intercellular spaces and accumulation of white blood cells and macrophages.
|
2 | Q9UP65 (/NAS) Q9UP65 (/NAS) |
|
Parturition GO:0007567
The reproductive process in which the parent is separated from its offspring either by giving birth to live young or by laying eggs.
|
2 | Q9UP65 (/NAS) Q9UP65 (/NAS) |
|
Arachidonic acid metabolic process GO:0019369
The chemical reactions and pathways involving arachidonic acid, a straight chain fatty acid with 20 carbon atoms and four double bonds per molecule. Arachidonic acid is the all-Z-(5,8,11,14)-isomer.
|
2 | Q9UP65 (/NAS) Q9UP65 (/NAS) |
|
Intracellular signal transduction GO:0035556
The process in which a signal is passed on to downstream components within the cell, which become activated themselves to further propagate the signal and finally trigger a change in the function or state of the cell.
|
2 | Q9UP65 (/NAS) Q9UP65 (/NAS) |
|
Phosphatidylinositol acyl-chain remodeling GO:0036149
Remodeling the acyl chains of phosphatidylinositol, through sequential deacylation and re-acylation reactions, to generate phosphatidylinositol containing different types of fatty acid acyl chains.
|
2 | Q9UP65 (/TAS) Q9UP65 (/TAS) |
|
Phosphatidylcholine acyl-chain remodeling GO:0036151
Remodeling the acyl chains of phosphatidylcholine, through sequential deacylation and re-acylation reactions, to generate phosphatidylcholine containing different types of fatty acid acyl chains.
|
2 | Q9UP65 (/TAS) Q9UP65 (/TAS) |
|
Phosphatidylethanolamine acyl-chain remodeling GO:0036152
Remodeling the acyl chains of phosphatidylethanolamine, through sequential deacylation and re-acylation reactions, to generate phosphatidylethanolamine containing different types of fatty acid acyl chains.
|
2 | Q9UP65 (/TAS) Q9UP65 (/TAS) |
|
Glycerophospholipid catabolic process GO:0046475
The chemical reactions and pathways resulting in the breakdown of glycerophospholipids, any derivative of glycerophosphate that contains at least one O-acyl, O-alkyl, or O-alkenyl group attached to the glycerol residue.
|
2 | Q9UP65 (/IDA) Q9UP65 (/IDA) |
There are 3 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Endoplasmic reticulum membrane GO:0005789
The lipid bilayer surrounding the endoplasmic reticulum.
|
2 | Q9UP65 (/TAS) Q9UP65 (/TAS) |
|
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
|
2 | Q9UP65 (/TAS) Q9UP65 (/TAS) |
|
Membrane GO:0016020
A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it.
|
2 | Q9UP65 (/TAS) Q9UP65 (/TAS) |
