The name of this superfamily has been modified since the most recent official CATH+ release (v4_4_0). At the point of the last release, this superfamily was named:

"
Cytosolic phospholipase A2 catalytic domain
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
« Back to all FunFams

FunFam 19: Patatin-like phospholipase domain-containing 2

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 3 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
2 P0C548 (/IPI) Q8BJ56 (/IPI)
Triglyceride lipase activity GO:0004806
Catalysis of the reaction: triacylglycerol + H2O = diacylglycerol + a carboxylate.
1 Q8BJ56 (/IDA)
Triglyceride lipase activity GO:0004806
Catalysis of the reaction: triacylglycerol + H2O = diacylglycerol + a carboxylate.
1 P0C548 (/ISS)

There are 10 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Negative regulation of sequestering of triglyceride GO:0010891
Any process that decreases the rate, frequency or extent of sequestering of triglyceride. Triglyceride sequestration is the process of binding or confining any triester of glycerol such that it is separated from other components of a biological system.
1 Q8BJ56 (/IDA)
Negative regulation of sequestering of triglyceride GO:0010891
Any process that decreases the rate, frequency or extent of sequestering of triglyceride. Triglyceride sequestration is the process of binding or confining any triester of glycerol such that it is separated from other components of a biological system.
1 Q8BJ56 (/ISO)
Negative regulation of sequestering of triglyceride GO:0010891
Any process that decreases the rate, frequency or extent of sequestering of triglyceride. Triglyceride sequestration is the process of binding or confining any triester of glycerol such that it is separated from other components of a biological system.
1 P0C548 (/ISS)
Positive regulation of triglyceride catabolic process GO:0010898
Any process that increases the frequency, rate, or extent of the chemical reactions and pathways resulting in the breakdown of triglyceride.
1 Q8BJ56 (/IDA)
Positive regulation of triglyceride catabolic process GO:0010898
Any process that increases the frequency, rate, or extent of the chemical reactions and pathways resulting in the breakdown of triglyceride.
1 Q8BJ56 (/ISO)
Positive regulation of triglyceride catabolic process GO:0010898
Any process that increases the frequency, rate, or extent of the chemical reactions and pathways resulting in the breakdown of triglyceride.
1 P0C548 (/ISS)
Triglyceride catabolic process GO:0019433
The chemical reactions and pathways resulting in the breakdown of a triglyceride, any triester of glycerol.
1 Q8BJ56 (/IMP)
Lipid storage GO:0019915
The accumulation and maintenance in cells or tissues of lipids, compounds soluble in organic solvents but insoluble or sparingly soluble in aqueous solvents. Lipid reserves can be accumulated during early developmental stages for mobilization and utilization at later stages of development.
1 Q8BJ56 (/IMP)
Lipid droplet organization GO:0034389
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a lipid particle.
1 Q8BJ56 (/IMP)
Cellular lipid catabolic process GO:0044242
The chemical reactions and pathways resulting in the breakdown of lipids, as carried out by individual cells.
1 Q8BJ56 (/IMP)

There are 4 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Nucleoplasm GO:0005654
That part of the nuclear content other than the chromosomes or the nucleolus.
1 Q8BJ56 (/ISO)
Lipid droplet GO:0005811
An intracellular non-membrane-bounded organelle comprising a matrix of coalesced lipids surrounded by a phospholipid monolayer. May include associated proteins.
1 Q8BJ56 (/IDA)
Lipid droplet GO:0005811
An intracellular non-membrane-bounded organelle comprising a matrix of coalesced lipids surrounded by a phospholipid monolayer. May include associated proteins.
1 Q8BJ56 (/ISO)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
1 Q8BJ56 (/IDA)
CATH-Gene3D is a Global Biodata Core Resource Learn more...