The name of this superfamily has been modified since the most recent official CATH+ release (v4_4_0). At the point of the last release, this superfamily was named:
"Cytosolic phospholipase A2 catalytic domain
".
FunFam 12: calcium-independent phospholipase A2-gamma isoform...
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 4 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
ATP binding GO:0005524
Interacting selectively and non-covalently with ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.
|
2 | Q9NP80 (/NAS) Q9NP80 (/NAS) |
|
Calcium-independent phospholipase A2 activity GO:0047499
Catalysis of the reaction: phosphatidylcholine + H2O = 1-acylglycerophosphocholine + a carboxylate. This reaction does not require Ca2+.
|
2 | Q9NP80 (/IDA) Q9NP80 (/IDA) |
|
Calcium-independent phospholipase A2 activity GO:0047499
Catalysis of the reaction: phosphatidylcholine + H2O = 1-acylglycerophosphocholine + a carboxylate. This reaction does not require Ca2+.
|
1 | Q8K1N1 (/ISO) |
|
Calcium-independent phospholipase A2 activity GO:0047499
Catalysis of the reaction: phosphatidylcholine + H2O = 1-acylglycerophosphocholine + a carboxylate. This reaction does not require Ca2+.
|
1 | Q8K1N1 (/ISS) |
There are 19 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Prostaglandin biosynthetic process GO:0001516
The chemical reactions and pathways resulting in the formation of prostaglandins, any of a group of biologically active metabolites which contain a cyclopentane ring.
|
2 | Q9NP80 (/IDA) Q9NP80 (/IDA) |
|
Fatty acid metabolic process GO:0006631
The chemical reactions and pathways involving fatty acids, aliphatic monocarboxylic acids liberated from naturally occurring fats and oils by hydrolysis.
|
2 | Q9NP80 (/IDA) Q9NP80 (/IDA) |
|
Cell death GO:0008219
Any biological process that results in permanent cessation of all vital functions of a cell. A cell should be considered dead when any one of the following molecular or morphological criteria is met: (1) the cell has lost the integrity of its plasma membrane; (2) the cell, including its nucleus, has undergone complete fragmentation into discrete bodies (frequently referred to as apoptotic bodies). The cell corpse (or its fragments) may be engulfed by an adjacent cell in vivo, but engulfment of whole cells should not be considered a strict criteria to define cell death as, under some circumstances, live engulfed cells can be released from phagosomes (see PMID:18045538).
|
2 | Q9NP80 (/IDA) Q9NP80 (/IDA) |
|
Arachidonic acid metabolic process GO:0019369
The chemical reactions and pathways involving arachidonic acid, a straight chain fatty acid with 20 carbon atoms and four double bonds per molecule. Arachidonic acid is the all-Z-(5,8,11,14)-isomer.
|
2 | Q9NP80 (/IDA) Q9NP80 (/IDA) |
|
Phosphatidylcholine catabolic process GO:0034638
The chemical reactions and pathways resulting in the breakdown of phosphatidylcholines, any of a class of glycerophospholipids in which the phosphatidyl group is esterified to the hydroxyl group of choline.
|
2 | Q9NP80 (/IDA) Q9NP80 (/IDA) |
|
Phosphatidylcholine acyl-chain remodeling GO:0036151
Remodeling the acyl chains of phosphatidylcholine, through sequential deacylation and re-acylation reactions, to generate phosphatidylcholine containing different types of fatty acid acyl chains.
|
2 | Q9NP80 (/TAS) Q9NP80 (/TAS) |
|
Phosphatidylethanolamine acyl-chain remodeling GO:0036152
Remodeling the acyl chains of phosphatidylethanolamine, through sequential deacylation and re-acylation reactions, to generate phosphatidylethanolamine containing different types of fatty acid acyl chains.
|
2 | Q9NP80 (/TAS) Q9NP80 (/TAS) |
|
Linoleic acid metabolic process GO:0043651
The chemical reactions and pathways involving linoleic acid, an unsaturated omega-6 fatty acid that has the molecular formula C18H32O2.
|
2 | Q9NP80 (/IDA) Q9NP80 (/IDA) |
|
Phosphatidylethanolamine catabolic process GO:0046338
The chemical reactions and pathways resulting in the breakdown of phosphatidylethanolamine, any of a class of glycerophospholipids in which a phosphatidyl group is esterified to the hydroxyl group of ethanolamine.
|
2 | Q9NP80 (/IDA) Q9NP80 (/IDA) |
|
Arachidonic acid secretion GO:0050482
The controlled release of arachidonic acid from a cell or a tissue.
|
2 | Q9NP80 (/IDA) Q9NP80 (/IDA) |
|
Prostaglandin biosynthetic process GO:0001516
The chemical reactions and pathways resulting in the formation of prostaglandins, any of a group of biologically active metabolites which contain a cyclopentane ring.
|
1 | Q8K1N1 (/ISO) |
|
Fatty acid metabolic process GO:0006631
The chemical reactions and pathways involving fatty acids, aliphatic monocarboxylic acids liberated from naturally occurring fats and oils by hydrolysis.
|
1 | Q8K1N1 (/ISO) |
|
Fatty acid metabolic process GO:0006631
The chemical reactions and pathways involving fatty acids, aliphatic monocarboxylic acids liberated from naturally occurring fats and oils by hydrolysis.
|
1 | Q8K1N1 (/ISS) |
|
Cell death GO:0008219
Any biological process that results in permanent cessation of all vital functions of a cell. A cell should be considered dead when any one of the following molecular or morphological criteria is met: (1) the cell has lost the integrity of its plasma membrane; (2) the cell, including its nucleus, has undergone complete fragmentation into discrete bodies (frequently referred to as apoptotic bodies). The cell corpse (or its fragments) may be engulfed by an adjacent cell in vivo, but engulfment of whole cells should not be considered a strict criteria to define cell death as, under some circumstances, live engulfed cells can be released from phagosomes (see PMID:18045538).
|
1 | Q8K1N1 (/ISO) |
|
Arachidonic acid metabolic process GO:0019369
The chemical reactions and pathways involving arachidonic acid, a straight chain fatty acid with 20 carbon atoms and four double bonds per molecule. Arachidonic acid is the all-Z-(5,8,11,14)-isomer.
|
1 | Q8K1N1 (/ISO) |
|
Phosphatidylcholine catabolic process GO:0034638
The chemical reactions and pathways resulting in the breakdown of phosphatidylcholines, any of a class of glycerophospholipids in which the phosphatidyl group is esterified to the hydroxyl group of choline.
|
1 | Q8K1N1 (/ISO) |
|
Linoleic acid metabolic process GO:0043651
The chemical reactions and pathways involving linoleic acid, an unsaturated omega-6 fatty acid that has the molecular formula C18H32O2.
|
1 | Q8K1N1 (/ISO) |
|
Phosphatidylethanolamine catabolic process GO:0046338
The chemical reactions and pathways resulting in the breakdown of phosphatidylethanolamine, any of a class of glycerophospholipids in which a phosphatidyl group is esterified to the hydroxyl group of ethanolamine.
|
1 | Q8K1N1 (/ISO) |
|
Arachidonic acid secretion GO:0050482
The controlled release of arachidonic acid from a cell or a tissue.
|
1 | Q8K1N1 (/ISO) |
There are 8 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Peroxisome GO:0005777
A small organelle enclosed by a single membrane, and found in most eukaryotic cells. Contains peroxidases and other enzymes involved in a variety of metabolic processes including free radical detoxification, lipid catabolism and biosynthesis, and hydrogen peroxide metabolism.
|
2 | Q9NP80 (/IDA) Q9NP80 (/IDA) |
|
Peroxisomal membrane GO:0005778
The lipid bilayer surrounding a peroxisome.
|
2 | Q9NP80 (/IDA) Q9NP80 (/IDA) |
|
Endoplasmic reticulum membrane GO:0005789
The lipid bilayer surrounding the endoplasmic reticulum.
|
2 | Q9NP80 (/TAS) Q9NP80 (/TAS) |
|
Membrane GO:0016020
A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it.
|
2 | Q9NP80 (/IDA) Q9NP80 (/IDA) |
|
Peroxisome GO:0005777
A small organelle enclosed by a single membrane, and found in most eukaryotic cells. Contains peroxidases and other enzymes involved in a variety of metabolic processes including free radical detoxification, lipid catabolism and biosynthesis, and hydrogen peroxide metabolism.
|
1 | Q8K1N1 (/ISO) |
|
Peroxisomal membrane GO:0005778
The lipid bilayer surrounding a peroxisome.
|
1 | Q8K1N1 (/ISO) |
|
Peroxisomal membrane GO:0005778
The lipid bilayer surrounding a peroxisome.
|
1 | Q8K1N1 (/ISS) |
|
Membrane GO:0016020
A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it.
|
1 | Q8K1N1 (/ISO) |
