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CATH Superfamily 3.10.450.300

YebF/Colicin-M immunity protein

The name of this superfamily has been modified since the most recent official CATH+ release (v4_4_0). At the point of the last release, this superfamily was named:

"
YebF/Colicin-M immunity protein
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.

Superfamily: YebF/Colicin-M immunity protein

This superfamily includes YebF-like proteins as well as colicin immunity proteins, such as cmi, the colicin M immunity protein PMID:16369539. This domain is found in bacteria, and is approximately 80 amino acids in length. The alignment contains two conserved cysteine residues that form a disulphide bond in the solved structure PMID:21037007.

Cmi protects cells from the colicin M toxin, though the mechanism by which it achieves this is not known PMID:2820942. The protein forms an alpha-beta fold and contains a disulphide bond that is essential for function PMID:21037007. Although the function of YbeF is not known, it is secreted by E. coli, and contains the two conserved cysteine residues responsible for the disulphide bond in Cmi PMID:16369539.

PFAM:PF13995,INTERPRO:IPR025603

GO Diversity

Unique GO annotations
0 Unique GO terms

EC Diversity

Unique EC annotations
0 Unique EC terms

Species Diversity

Unique species annotations
350 Unique species

Sequence/Structure Diversity

Overview of the sequence / structure diversity of this superfamily compared to other superfamilies in CATH. Click on the chart to view the data in more detail.

Superfamily Summary

A general summary of information for this superfamily.
Structures
Domains: 3
Domain clusters (>95% seq id): 2
Domain clusters (>35% seq id): 2
Unique PDBs: 2
Alignments
Structural Clusters (5A): 1
Structural Clusters (9A): 1
FunFam Clusters: 0
Function
Unique EC:
Unique GO:
Taxonomy
Unique Species: 350
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