The name of this superfamily has been modified since the most recent official CATH+ release (v4_4_0). At the point of the last release, this superfamily was named:
"Immunoglobulins
".
FunFam 3075: CD226 antigen (Predicted), isoform CRA_b
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 4 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Integrin binding GO:0005178
Interacting selectively and non-covalently with an integrin.
|
2 | Q8K4F0 (/ISO) Q8K4F0 (/ISO) |
|
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
|
2 | Q8K4F0 (/IPI) Q8K4F0 (/IPI) |
|
Protein kinase binding GO:0019901
Interacting selectively and non-covalently with a protein kinase, any enzyme that catalyzes the transfer of a phosphate group, usually from ATP, to a protein substrate.
|
2 | Q8K4F0 (/ISO) Q8K4F0 (/ISO) |
|
Cell adhesion molecule binding GO:0050839
Interacting selectively and non-covalently with a cell adhesion molecule.
|
2 | Q8K4F0 (/ISO) Q8K4F0 (/ISO) |
There are 9 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Cytokine production GO:0001816
The appearance of a cytokine due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.
|
2 | Q8K4F0 (/IDA) Q8K4F0 (/IDA) |
|
Positive regulation of natural killer cell cytokine production GO:0002729
Any process that activates or increases the frequency, rate, or extent of natural killer cell cytokine production.
|
2 | Q8K4F0 (/IMP) Q8K4F0 (/IMP) |
|
Positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target GO:0002860
Any process that activates or increases the frequency, rate, or extent of natural killer cell mediated cytotoxicity directed against tumor cell target.
|
2 | Q8K4F0 (/ISO) Q8K4F0 (/ISO) |
|
Positive regulation of immunoglobulin mediated immune response GO:0002891
Any process that activates or increases the frequency, rate, or extent of an immunoglobulin mediated immune response.
|
2 | Q8K4F0 (/ISO) Q8K4F0 (/ISO) |
|
Positive regulation of interferon-gamma production GO:0032729
Any process that activates or increases the frequency, rate, or extent of interferon-gamma production. Interferon-gamma is also known as type II interferon.
|
2 | Q8K4F0 (/IMP) Q8K4F0 (/IMP) |
|
Positive regulation of mast cell activation GO:0033005
Any process that activates or increases the frequency, rate, or extent of mast cell activation.
|
2 | Q8K4F0 (/ISO) Q8K4F0 (/ISO) |
|
Positive regulation of natural killer cell mediated cytotoxicity GO:0045954
Any process that activates or increases the frequency, rate or extent of natural killer cell mediated cytotoxicity.
|
2 | Q8K4F0 (/ISO) Q8K4F0 (/ISO) |
|
Positive regulation of T cell receptor signaling pathway GO:0050862
Any process that activates or increases the frequency, rate or extent of signaling pathways initiated by the cross-linking of an antigen receptor on a T cell.
|
2 | Q8K4F0 (/ISO) Q8K4F0 (/ISO) |
|
Positive regulation of Fc receptor mediated stimulatory signaling pathway GO:0060369
Any process that increases the rate, frequency or extent of the Fc receptor mediated stimulatory signaling pathway. The Fc receptor mediated stimulatory signaling pathway is a series of molecular signals generated as a consequence of a the binding of the Fc portion of an immunoglobulin by an Fc receptor capable of activating or perpetuating an immune response. The Fc portion of an immunoglobulin is its C-terminal constant region.
|
2 | Q8K4F0 (/ISO) Q8K4F0 (/ISO) |
There are 2 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
External side of plasma membrane GO:0009897
The leaflet of the plasma membrane that faces away from the cytoplasm and any proteins embedded or anchored in it or attached to its surface.
|
2 | Q8K4F0 (/IDA) Q8K4F0 (/IDA) |
|
Cell surface GO:0009986
The external part of the cell wall and/or plasma membrane.
|
2 | Q8K4F0 (/ISO) Q8K4F0 (/ISO) |
