The name of this superfamily has been modified since the most recent official CATH+ release (v4_4_0). At the point of the last release, this superfamily was named:
"Immunoglobulins
".
FunFam 2256: Interferon alpha/beta receptor 1a
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 2 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Interferon receptor activity GO:0004904
Combining with an interferon and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.
|
5 | A0AUQ9 (/IGI) A0FJI0 (/IGI) A5PF68 (/IGI) F1QA77 (/IGI) Q3HSD4 (/IGI) |
|
Type I interferon receptor activity GO:0004905
Combining with a type I interferon and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity. Type I interferons include the interferon-alpha, beta, delta, epsilon, zeta, kappa, tau, and omega gene families.
|
1 | K7NAJ3 (/IMP) |
There are 3 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Immune response-activating signal transduction GO:0002757
The cascade of processes by which a signal interacts with a receptor, causing a change in the level or activity of a second messenger or other downstream target, and ultimately leading to activation or perpetuation of an immune response.
|
5 | A0AUQ9 (/IC) A0FJI0 (/IC) A5PF68 (/IC) F1QA77 (/IC) Q3HSD4 (/IC) |
|
Positive regulation of protein phosphorylation GO:0001934
Any process that activates or increases the frequency, rate or extent of addition of phosphate groups to amino acids within a protein.
|
1 | K7NAJ3 (/IMP) |
|
Type I interferon signaling pathway GO:0060337
A series of molecular signals initiated by the binding of a type I interferon to a receptor on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription. Type I interferons include the interferon-alpha, beta, delta, episilon, zeta, kappa, tau, and omega gene families.
|
1 | K7NA32 (/IMP) |
There are 4 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Integral component of membrane GO:0016021
The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
|
5 | A0AUQ9 (/IC) A0FJI0 (/IC) A5PF68 (/IC) F1QA77 (/IC) Q3HSD4 (/IC) |
|
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
|
1 | K7NAJ3 (/IDA) |
|
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
|
1 | K7NAJ3 (/IDA) |
|
Perinuclear region of cytoplasm GO:0048471
Cytoplasm situated near, or occurring around, the nucleus.
|
1 | K7NAJ3 (/IDA) |
