The name of this superfamily has been modified since the most recent official CATH+ release (v4_4_0). At the point of the last release, this superfamily was named:
"Immunoglobulins
".
FunFam 2097: CD160 antigen
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 13 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
|
5 | O88875 (/IPI) O95971 (/IPI) O95971 (/IPI) O95971 (/IPI) O95971 (/IPI) |
|
Signaling receptor binding GO:0005102
Interacting selectively and non-covalently with one or more specific sites on a receptor molecule, a macromolecule that undergoes combination with a hormone, neurotransmitter, drug or intracellular messenger to initiate a change in cell function.
|
4 | O95971 (/IDA) O95971 (/IDA) O95971 (/IDA) O95971 (/IDA) |
|
Kinase binding GO:0019900
Interacting selectively and non-covalently with a kinase, any enzyme that catalyzes the transfer of a phosphate group.
|
4 | O95971 (/IPI) O95971 (/IPI) O95971 (/IPI) O95971 (/IPI) |
|
MHC class I receptor activity GO:0032393
Combining with an MHC class I protein complex to initiate a change in cellular activity. Class I here refers to classical class I molecules.
|
4 | O95971 (/IDA) O95971 (/IDA) O95971 (/IDA) O95971 (/IDA) |
|
MHC class Ib receptor activity GO:0032394
Combining with an MHC class Ib protein complex and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity. Class Ib here refers to non-classical class I molecules, such as those of the CD1 or HLA-E gene families.
|
4 | O95971 (/IDA) O95971 (/IDA) O95971 (/IDA) O95971 (/IDA) |
|
Activating MHC class I receptor activity GO:0032397
Combining with a MHC class I protein complex to mediate signaling that activates a lymphocyte.
|
4 | O95971 (/IDA) O95971 (/IDA) O95971 (/IDA) O95971 (/IDA) |
|
Signaling receptor binding GO:0005102
Interacting selectively and non-covalently with one or more specific sites on a receptor molecule, a macromolecule that undergoes combination with a hormone, neurotransmitter, drug or intracellular messenger to initiate a change in cell function.
|
1 | O88875 (/ISO) |
|
Kinase binding GO:0019900
Interacting selectively and non-covalently with a kinase, any enzyme that catalyzes the transfer of a phosphate group.
|
1 | O88875 (/ISO) |
|
MHC class I protein complex binding GO:0023024
Interacting selectively and non-covalently with the class I major histocompatibility complex.
|
1 | O88875 (/IDA) |
|
MHC class I receptor activity GO:0032393
Combining with an MHC class I protein complex to initiate a change in cellular activity. Class I here refers to classical class I molecules.
|
1 | O88875 (/ISO) |
|
MHC class Ib receptor activity GO:0032394
Combining with an MHC class Ib protein complex and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity. Class Ib here refers to non-classical class I molecules, such as those of the CD1 or HLA-E gene families.
|
1 | O88875 (/ISO) |
|
Activating MHC class I receptor activity GO:0032397
Combining with a MHC class I protein complex to mediate signaling that activates a lymphocyte.
|
1 | O88875 (/ISO) |
|
Activating MHC class I receptor activity GO:0032397
Combining with a MHC class I protein complex to mediate signaling that activates a lymphocyte.
|
1 | O88875 (/ISS) |
There are 28 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Positive regulation of natural killer cell cytokine production GO:0002729
Any process that activates or increases the frequency, rate, or extent of natural killer cell cytokine production.
|
4 | O95971 (/IDA) O95971 (/IDA) O95971 (/IDA) O95971 (/IDA) |
|
Phosphatidylinositol 3-kinase signaling GO:0014065
A series of reactions within the signal-receiving cell, mediated by the intracellular phosphatidylinositol 3-kinase (PI3K). Many cell surface receptor linked signaling pathways signal through PI3K to regulate numerous cellular functions.
|
4 | O95971 (/IDA) O95971 (/IDA) O95971 (/IDA) O95971 (/IDA) |
|
Negative regulation of angiogenesis GO:0016525
Any process that stops, prevents, or reduces the frequency, rate or extent of angiogenesis.
|
4 | O95971 (/IDA) O95971 (/IDA) O95971 (/IDA) O95971 (/IDA) |
|
T cell costimulation GO:0031295
The process of providing, via surface-bound receptor-ligand pairs, a second, antigen-independent, signal in addition to that provided by the T cell receptor to augment T cell activation.
|
4 | O95971 (/IDA) O95971 (/IDA) O95971 (/IDA) O95971 (/IDA) |
|
Positive regulation of natural killer cell mediated cytotoxicity GO:0045954
Any process that activates or increases the frequency, rate or extent of natural killer cell mediated cytotoxicity.
|
4 | O95971 (/IDA) O95971 (/IDA) O95971 (/IDA) O95971 (/IDA) |
|
Regulation of immune response GO:0050776
Any process that modulates the frequency, rate or extent of the immune response, the immunological reaction of an organism to an immunogenic stimulus.
|
4 | O95971 (/TAS) O95971 (/TAS) O95971 (/TAS) O95971 (/TAS) |
|
Negative regulation of T cell receptor signaling pathway GO:0050860
Any process that stops, prevents, or reduces the frequency, rate or extent of signaling pathways initiated by the cross-linking of an antigen receptor on a T cell.
|
4 | O95971 (/IDA) O95971 (/IDA) O95971 (/IDA) O95971 (/IDA) |
|
Negative regulation of CD4-positive, alpha-beta T cell costimulation GO:1900280
Any process that stops, prevents or reduces the frequency, rate or extent of CD4-positive, alpha-beta T cell costimulation.
|
4 | O95971 (/IDA) O95971 (/IDA) O95971 (/IDA) O95971 (/IDA) |
|
Negative regulation of adaptive immune memory response GO:1905675
Any process that stops, prevents or reduces the frequency, rate or extent of adaptive immune memory response.
|
4 | O95971 (/IDA) O95971 (/IDA) O95971 (/IDA) O95971 (/IDA) |
|
Positive regulation of endothelial cell apoptotic process GO:2000353
Any process that activates or increases the frequency, rate or extent of endothelial cell apoptotic process.
|
4 | O95971 (/IDA) O95971 (/IDA) O95971 (/IDA) O95971 (/IDA) |
|
Mucosal immune response GO:0002385
An immune response taking place in mucosal tissues, including those of the intestinal tract, nasal and upper respiratory tract, and genital tract.
|
1 | O88875 (/IDA) |
|
Positive regulation of natural killer cell cytokine production GO:0002729
Any process that activates or increases the frequency, rate, or extent of natural killer cell cytokine production.
|
1 | O88875 (/ISO) |
|
Positive regulation of natural killer cell cytokine production GO:0002729
Any process that activates or increases the frequency, rate, or extent of natural killer cell cytokine production.
|
1 | O88875 (/ISS) |
|
Positive regulation of natural killer cell mediated immune response to tumor cell GO:0002857
Any process that activates or increases the frequency, rate, or extent of natural killer cell mediated immune response to a tumor cell.
|
1 | O88875 (/IMP) |
|
Phosphatidylinositol 3-kinase signaling GO:0014065
A series of reactions within the signal-receiving cell, mediated by the intracellular phosphatidylinositol 3-kinase (PI3K). Many cell surface receptor linked signaling pathways signal through PI3K to regulate numerous cellular functions.
|
1 | O88875 (/ISO) |
|
Phosphatidylinositol 3-kinase signaling GO:0014065
A series of reactions within the signal-receiving cell, mediated by the intracellular phosphatidylinositol 3-kinase (PI3K). Many cell surface receptor linked signaling pathways signal through PI3K to regulate numerous cellular functions.
|
1 | O88875 (/ISS) |
|
Negative regulation of angiogenesis GO:0016525
Any process that stops, prevents, or reduces the frequency, rate or extent of angiogenesis.
|
1 | O88875 (/ISO) |
|
T cell costimulation GO:0031295
The process of providing, via surface-bound receptor-ligand pairs, a second, antigen-independent, signal in addition to that provided by the T cell receptor to augment T cell activation.
|
1 | O88875 (/ISO) |
|
T cell costimulation GO:0031295
The process of providing, via surface-bound receptor-ligand pairs, a second, antigen-independent, signal in addition to that provided by the T cell receptor to augment T cell activation.
|
1 | O88875 (/ISS) |
|
Positive regulation of natural killer cell degranulation GO:0043323
Any process that activates or increases the frequency, rate or extent of natural killer cell degranulation.
|
1 | O88875 (/ISO) |
|
Positive regulation of natural killer cell mediated cytotoxicity GO:0045954
Any process that activates or increases the frequency, rate or extent of natural killer cell mediated cytotoxicity.
|
1 | O88875 (/ISO) |
|
Positive regulation of natural killer cell mediated cytotoxicity GO:0045954
Any process that activates or increases the frequency, rate or extent of natural killer cell mediated cytotoxicity.
|
1 | O88875 (/ISS) |
|
Defense response to Gram-negative bacterium GO:0050829
Reactions triggered in response to the presence of a Gram-negative bacterium that act to protect the cell or organism.
|
1 | O88875 (/IMP) |
|
Negative regulation of T cell receptor signaling pathway GO:0050860
Any process that stops, prevents, or reduces the frequency, rate or extent of signaling pathways initiated by the cross-linking of an antigen receptor on a T cell.
|
1 | O88875 (/ISO) |
|
Negative regulation of CD4-positive, alpha-beta T cell costimulation GO:1900280
Any process that stops, prevents or reduces the frequency, rate or extent of CD4-positive, alpha-beta T cell costimulation.
|
1 | O88875 (/ISO) |
|
Positive regulation of interferon-gamma secretion GO:1902715
Any process that activates or increases the frequency, rate or extent of interferon-gamma secretion.
|
1 | O88875 (/IMP) |
|
Negative regulation of adaptive immune memory response GO:1905675
Any process that stops, prevents or reduces the frequency, rate or extent of adaptive immune memory response.
|
1 | O88875 (/ISO) |
|
Positive regulation of endothelial cell apoptotic process GO:2000353
Any process that activates or increases the frequency, rate or extent of endothelial cell apoptotic process.
|
1 | O88875 (/ISO) |
There are 6 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
|
5 | O88875 (/IDA) O95971 (/IDA) O95971 (/IDA) O95971 (/IDA) O95971 (/IDA) |
|
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
|
4 | O95971 (/TAS) O95971 (/TAS) O95971 (/TAS) O95971 (/TAS) |
|
Anchored component of plasma membrane GO:0046658
The component of the plasma membrane consisting of the gene products that are tethered to the membrane only by a covalently attached anchor, such as a lipid group, that is embedded in the membrane. Gene products with peptide sequences that are embedded in the membrane are excluded from this grouping.
|
4 | O95971 (/IDA) O95971 (/IDA) O95971 (/IDA) O95971 (/IDA) |
|
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
|
1 | O88875 (/ISO) |
|
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
|
1 | O88875 (/ISS) |
|
Anchored component of plasma membrane GO:0046658
The component of the plasma membrane consisting of the gene products that are tethered to the membrane only by a covalently attached anchor, such as a lipid group, that is embedded in the membrane. Gene products with peptide sequences that are embedded in the membrane are excluded from this grouping.
|
1 | O88875 (/ISO) |
