The name of this superfamily has been modified since the most recent official CATH+ release (v4_4_0). At the point of the last release, this superfamily was named:

"
Immunoglobulins
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 1687: Neuroglian, isoform E

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 5 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
4 Q18100 (/IPI) Q4PIU9 (/IPI) Q53U86 (/IPI) Q53U87 (/IPI)
Ankyrin binding GO:0030506
Interacting selectively and non-covalently with ankyrin, a 200 kDa cytoskeletal protein that attaches other cytoskeletal proteins to integral membrane proteins.
4 Q18100 (/IPI) Q4PIU9 (/IPI) Q53U86 (/IPI) Q53U87 (/IPI)
Cell adhesion molecule binding GO:0050839
Interacting selectively and non-covalently with a cell adhesion molecule.
4 Q18100 (/ISS) Q4PIU9 (/ISS) Q53U86 (/ISS) Q53U87 (/ISS)
Cell adhesion molecule binding GO:0050839
Interacting selectively and non-covalently with a cell adhesion molecule.
3 P20241 (/IPI) P20241 (/IPI) Q90933 (/IPI)
Calcium ion binding GO:0005509
Interacting selectively and non-covalently with calcium ions (Ca2+).
2 P20241 (/IDA) P20241 (/IDA)

There are 32 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Establishment of mitotic spindle orientation GO:0000132
A cell cycle process that sets the alignment of mitotic spindle relative to other cellular structures.
4 Q18100 (/IGI) Q4PIU9 (/IGI) Q53U86 (/IGI) Q53U87 (/IGI)
Apical constriction involved in gastrulation GO:0003384
The actin-mediated process that results in the contraction of the apical end of a polarized columnar epithelial cell, contributing to the process of gastrulation.
4 Q18100 (/IGI) Q4PIU9 (/IGI) Q53U86 (/IGI) Q53U87 (/IGI)
Embryo development ending in birth or egg hatching GO:0009792
The process whose specific outcome is the progression of an embryo over time, from zygote formation until the end of the embryonic life stage. The end of the embryonic life stage is organism-specific and may be somewhat arbitrary; for mammals it is usually considered to be birth, for insects the hatching of the first instar larva from the eggshell.
4 Q18100 (/IMP) Q4PIU9 (/IMP) Q53U86 (/IMP) Q53U87 (/IMP)
Cell migration involved in gastrulation GO:0042074
The migration of individual cells within the blastocyst to help establish the multi-layered body plan of the organism (gastrulation). For example, the migration of cells from the surface to the interior of the embryo (ingression).
4 Q18100 (/IGI) Q4PIU9 (/IGI) Q53U86 (/IGI) Q53U87 (/IGI)
Dendrite morphogenesis GO:0048813
The process in which the anatomical structures of a dendrite are generated and organized.
3 P20241 (/IMP) P20241 (/IMP) Q53U87 (/IMP)
Neuron cell-cell adhesion GO:0007158
The attachment of a neuron to another cell via adhesion molecules.
2 P20241 (/IMP) P20241 (/IMP)
Axonogenesis GO:0007409
De novo generation of a long process of a neuron, including the terminal branched region. Refers to the morphogenesis or creation of shape or form of the developing axon, which carries efferent (outgoing) action potentials from the cell body towards target cells.
2 P20241 (/IMP) P20241 (/IMP)
Imaginal disc morphogenesis GO:0007560
The process in which the anatomical structures derived from an imaginal disc are generated and organized. The imaginal discs are epithelial infoldings in the larvae of holometabolous insects that develop into adult appendages (legs, antennae, wings, etc.) during metamorphosis from larval to adult form.
2 P20241 (/IMP) P20241 (/IMP)
Motor neuron axon guidance GO:0008045
The process in which the migration of an axon growth cone of a motor neuron is directed to a specific target site in response to a combination of attractive and repulsive cues.
2 P20241 (/IMP) P20241 (/IMP)
Male courtship behavior GO:0008049
The behavior of a male, for the purpose of attracting a sexual partner. An example of this process is found in Drosophila melanogaster.
2 P20241 (/IMP) P20241 (/IMP)
Female courtship behavior GO:0008050
The behavior of a female, for the purpose of attracting a sexual partner.
2 P20241 (/IMP) P20241 (/IMP)
Axon ensheathment GO:0008366
Any process in which the axon of a neuron is insulated, and that insulation maintained, thereby preventing dispersion of the electrical signal.
2 P20241 (/IMP) P20241 (/IMP)
Mushroom body development GO:0016319
The process whose specific outcome is the progression of the mushroom body over time, from its formation to the mature structure. The mushroom body is composed of the prominent neuropil structures of the insect central brain, thought to be crucial for olfactory associated learning. These consist mainly of a bulbous calyx and tightly packaged arrays of thin parallel fibers of the Kenyon cells.
2 P20241 (/IMP) P20241 (/IMP)
Septate junction assembly GO:0019991
The assembly of a septate junction, an intercellular junction found in invertebrate epithelia that is characterized by a ladder like appearance in electron micrographs and thought to provide structural strength and to provide a barrier to diffusion of solutes through the intercellular space.
2 P20241 (/IMP) P20241 (/IMP)
Nerve maturation GO:0021682
A developmental process, independent of morphogenetic (shape) change, that is required for a nerve to attain its fully functional state.
2 P20241 (/IMP) P20241 (/IMP)
Melanotic encapsulation of foreign target GO:0035011
Formation of a multilayered, melanized sheath of cells around a foreign invader.
2 P20241 (/IMP) P20241 (/IMP)
Regulation of tube size, open tracheal system GO:0035151
Ensuring that an epithelial tube in an open tracheal system is of the correct length and diameter. Tracheal tubes undergo highly regulated tube-size increases during development, expanding up to 40 times their initial size by the end of larval life. Tube size appears to be controlled by regulation of apical membrane expansion and secretion, rather than by changes in cell number, size or shape.
2 P20241 (/IMP) P20241 (/IMP)
Regulation of female receptivity GO:0045924
Any process that modulates the frequency, rate or extent of the willingness or readiness of a female to receive male advances.
2 P20241 (/IMP) P20241 (/IMP)
Central complex development GO:0048036
The process whose specific outcome is the progression of the central complex over time, from its formation to the mature structure. The central complex region of the insect brain is thought to be crucial for control of locomotive behavior. Located in the middle of the two protocerebral hemispheres, it comprises four neuropilar regions, the fan-shaped body, the ellipsoid body, the protocerebral bridge and the paired noduli.
2 P20241 (/IMP) P20241 (/IMP)
Axon extension GO:0048675
Long distance growth of a single axon process involved in cellular development.
2 P20241 (/IMP) P20241 (/IMP)
Synapse organization GO:0050808
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a synapse, the junction between a neuron and a target (neuron, muscle, or secretory cell).
2 P20241 (/IMP) P20241 (/IMP)
Establishment of glial blood-brain barrier GO:0060857
Establishment of the glial barrier between the blood and the brain. The glial cells in the brain are packed tightly together preventing the passage of most molecules from the blood into the brain. Only lipid soluble molecules or those that are actively transported can pass through the blood-brain barrier.
2 P20241 (/IMP) P20241 (/IMP)
Cell adhesion involved in heart morphogenesis GO:0061343
The attachment of a cell, either to another cell or to an underlying substrate such as the extracellular matrix, via cell adhesion molecules that contributes to the shaping of the heart.
2 P20241 (/IMP) P20241 (/IMP)
Photoreceptor cell axon guidance GO:0072499
The chemotaxis process that directs the migration of a photoreceptor cell axon growth cone to its target in the optic lobe in response to a combination of attractive and repulsive cues.
2 P20241 (/IMP) P20241 (/IMP)
Cell-cell adhesion GO:0098609
The attachment of one cell to another cell via adhesion molecules.
2 P20241 (/IDA) P20241 (/IDA)
Regulation of dendrite morphogenesis GO:0048814
Any process that modulates the frequency, rate or extent of dendrite morphogenesis.
1 Q53U87 (/IGI)
Positive regulation of dendrite morphogenesis GO:0050775
Any process that activates or increases the frequency, rate or extent of dendrite morphogenesis.
1 Q53U87 (/IGI)
Positive regulation of dendrite morphogenesis GO:0050775
Any process that activates or increases the frequency, rate or extent of dendrite morphogenesis.
1 Q53U87 (/IMP)
Dendrite self-avoidance GO:0070593
The process in which dendrites recognize and avoid contact with sister dendrites from the same cell.
1 Q53U87 (/IGI)
Dendrite self-avoidance GO:0070593
The process in which dendrites recognize and avoid contact with sister dendrites from the same cell.
1 Q53U87 (/IMP)
Regulation of dendrite extension GO:1903859
Any process that modulates the frequency, rate or extent of dendrite extension.
1 Q53U87 (/IGI)
Regulation of dendrite extension GO:1903859
Any process that modulates the frequency, rate or extent of dendrite extension.
1 Q53U87 (/IMP)

There are 14 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
6 P20241 (/IDA) P20241 (/IDA) Q18100 (/IDA) Q4PIU9 (/IDA) Q53U86 (/IDA) Q53U87 (/IDA)
Cell-cell adherens junction GO:0005913
An adherens junction which connects a cell to another cell.
4 Q18100 (/IDA) Q4PIU9 (/IDA) Q53U86 (/IDA) Q53U87 (/IDA)
Lateral plasma membrane GO:0016328
The portion of the plasma membrane at the lateral side of the cell. In epithelial cells, lateral plasma membranes are on the sides of cells which lie at the interface of adjacent cells.
4 Q18100 (/IDA) Q4PIU9 (/IDA) Q53U86 (/IDA) Q53U87 (/IDA)
Sarcomere GO:0030017
The repeating unit of a myofibril in a muscle cell, composed of an array of overlapping thick and thin filaments between two adjacent Z discs.
4 Q18100 (/IDA) Q4PIU9 (/IDA) Q53U86 (/IDA) Q53U87 (/IDA)
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
2 P20241 (/HDA) P20241 (/HDA)
Integral component of plasma membrane GO:0005887
The component of the plasma membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
2 P20241 (/IDA) P20241 (/IDA)
Septate junction GO:0005918
A cell-cell junction that forms a continuous band around each cell in an epithelium; within the septate junction the membranes of adjacent cells maintain a constant distance of approximately 15 nm; found in arthropods.
2 P20241 (/IDA) P20241 (/IDA)
Pleated septate junction GO:0005919
A septate junction in which regular arrays of electron-dense septae span the intermembrane space.
2 P20241 (/IDA) P20241 (/IDA)
Filopodium GO:0030175
Thin, stiff, actin-based protrusion extended by the leading edge of a motile cell such as a crawling fibroblast or amoeba, or an axonal or dendritic growth cone, or a dendritic shaft.
2 P20241 (/IDA) P20241 (/IDA)
Axon GO:0030424
The long process of a neuron that conducts nerve impulses, usually away from the cell body to the terminals and varicosities, which are sites of storage and release of neurotransmitter.
1 Q90933 (/IDA)
Axolemma GO:0030673
The portion of the plasma membrane surrounding an axon; it is a specialized trilaminar random mosaic of protein molecules floating within a fluid matrix of highly mobile phospholipid molecules, 7-8 nm in thickness.
1 Q18100 (/IDA)
Dendrite membrane GO:0032590
The portion of the plasma membrane surrounding a dendrite.
1 Q18100 (/IDA)
Neuronal cell body membrane GO:0032809
The plasma membrane of a neuron cell body - excludes the plasma membrane of cell projections such as axons and dendrites.
1 Q18100 (/IDA)
Axonal growth cone GO:0044295
The migrating motile tip of a growing nerve cell axon.
1 Q90933 (/IDA)
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