The name of this superfamily has been modified since the most recent official CATH+ release (v4_4_0). At the point of the last release, this superfamily was named:
"Immunoglobulins
".
FunFam 1297: Interleukin 18 binding protein
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 5 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
|
2 | F7F5P4 (/IPI) Q9JLN2 (/IPI) |
|
Interleukin-18 binding GO:0042007
Interacting selectively and non-covalently with interleukin-18.
|
2 | O95998 (/IDA) O95998 (/IDA) |
|
Receptor antagonist activity GO:0048019
The activity of a gene product that interacts with a receptor to decrease the ability of the receptor agonist to bind and activate the receptor.
|
2 | O95998 (/TAS) O95998 (/TAS) |
|
Interleukin-18 binding GO:0042007
Interacting selectively and non-covalently with interleukin-18.
|
1 | Q9Z0M9 (/ISO) |
|
Interleukin-18 binding GO:0042007
Interacting selectively and non-covalently with interleukin-18.
|
1 | Q9Z0M9 (/ISS) |
There are 8 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Response to lipopolysaccharide GO:0032496
Any process that results in a change in state or activity of an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a lipopolysaccharide stimulus; lipopolysaccharide is a major component of the cell wall of gram-negative bacteria.
|
2 | F7F5P4 (/IEP) Q9JLN2 (/IEP) |
|
Interleukin-18-mediated signaling pathway GO:0035655
A series of molecular signals initiated by the binding of interleukin-18 to a receptor on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription.
|
2 | O95998 (/TAS) O95998 (/TAS) |
|
T-helper 1 type immune response GO:0042088
An immune response which is associated with resistance to intracellular bacteria, fungi, and protozoa, and pathological conditions such as arthritis, and which is typically orchestrated by the production of particular cytokines by T-helper 1 cells, most notably interferon-gamma, IL-2, and lymphotoxin.
|
2 | O95998 (/IDA) O95998 (/IDA) |
|
Cellular response to hydrogen peroxide GO:0070301
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a hydrogen peroxide (H2O2) stimulus.
|
2 | F7F5P4 (/IEP) Q9JLN2 (/IEP) |
|
Cellular response to cytokine stimulus GO:0071345
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cytokine stimulus.
|
2 | O95998 (/TAS) O95998 (/TAS) |
|
Cellular response to tumor necrosis factor GO:0071356
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a tumor necrosis factor stimulus.
|
2 | F7F5P4 (/IEP) Q9JLN2 (/IEP) |
|
T-helper 1 type immune response GO:0042088
An immune response which is associated with resistance to intracellular bacteria, fungi, and protozoa, and pathological conditions such as arthritis, and which is typically orchestrated by the production of particular cytokines by T-helper 1 cells, most notably interferon-gamma, IL-2, and lymphotoxin.
|
1 | Q9Z0M9 (/ISO) |
|
T-helper 1 type immune response GO:0042088
An immune response which is associated with resistance to intracellular bacteria, fungi, and protozoa, and pathological conditions such as arthritis, and which is typically orchestrated by the production of particular cytokines by T-helper 1 cells, most notably interferon-gamma, IL-2, and lymphotoxin.
|
1 | Q9Z0M9 (/ISS) |
There are 4 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Extracellular region GO:0005576
The space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane. This term covers the host cell environment outside an intracellular parasite.
|
2 | O95998 (/TAS) O95998 (/TAS) |
|
Extracellular space GO:0005615
That part of a multicellular organism outside the cells proper, usually taken to be outside the plasma membranes, and occupied by fluid.
|
2 | F7F5P4 (/IDA) Q9JLN2 (/IDA) |
|
Extracellular exosome GO:0070062
A vesicle that is released into the extracellular region by fusion of the limiting endosomal membrane of a multivesicular body with the plasma membrane. Extracellular exosomes, also simply called exosomes, have a diameter of about 40-100 nm.
|
2 | O95998 (/HDA) O95998 (/HDA) |
|
Extracellular space GO:0005615
That part of a multicellular organism outside the cells proper, usually taken to be outside the plasma membranes, and occupied by fluid.
|
1 | Q9Z0M9 (/ISO) |
