CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
2 | Mainly Beta |
|
2.40 | Beta Barrel |
|
2.40.290 | Ku70; Chain: A; Domain 2 |
|
2.40.290.10 |
Domain Context
CATH Clusters
| Superfamily | 2.40.290.10 |
| Functional Family | X-ray repair cross-complementing protein 5 |
Enzyme Information
| 3.6.4.- |
Acting on ATP; involved in cellular and subcellular movement.
based on mapping to UniProt P13010
|
UniProtKB Entries (1)
| Q8IW19 |
APLF_HUMAN
Homo sapiens
Aprataxin and PNK-like factor
|
PDB Structure
| PDB | 6ERF |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
XLF and APLF bind Ku80 at two remote sites to ensure DNA repair by non-homologous end joining.
Nat. Struct. Mol. Biol.
|
