CATH Domain 5jsbD00

CATH Classification

Level	CATH Code	Description
	1	Mainly Alpha
	1.10	Orthogonal Bundle
	1.10.132	Topoisomerase I; Chain A, domain 4
	1.10.132.20	Ribosome-recycling factor

Domain Context

CATH Clusters

Superfamily	Ribosome-recycling factor
Functional Family

Enzyme Information

UniProtKB Entries (1)

MCL1_HUMAN

Homo sapiens

Induced myeloid leukemia cell differentiation protein Mcl-1

PDB Structure

PDB	5JSB
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Computationally designed high specificity inhibitors delineate the roles of BCL2 family proteins in cancer. Berger, S., Procko, E., Margineantu, D., Lee, E.F., Shen, B.W., Zelter, A., Silva, D.A., Chawla, K., Herold, M.J., Garnier, J.M., Johnson, R., MacCoss, M.J., Lessene, G., Davis, T.N., Stayton, P.S., Stoddard, B.L., Fairlie, W.D., Hockenbery, D.M., Baker, D. Elife