CATH Domain 4i43B02

CATH Classification

Level	CATH Code	Description
	3	Alpha Beta
	3.30	2-Layer Sandwich
	3.30.43	Uridine Diphospho-n-acetylenolpyruvylglucosamine Reductase; domain 2
	3.30.43.40	Pre-mRNA-processing-splicing factor 8, U5-snRNA-binding domain

Domain Context

CATH Clusters

Superfamily	Pre-mRNA-processing-splicing factor 8, U5-snRNA-binding domain
Functional Family	Pre-mRNA-processing-splicing factor 8

Enzyme Information

UniProtKB Entries (1)

PRP8_YEAST

Saccharomyces cerevisiae S288C

Pre-mRNA-splicing factor 8

PDB Structure

PDB	4I43
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Crystal structure of Prp8 reveals active site cavity of the spliceosome. Galej, W.P., Oubridge, C., Newman, A.J., Nagai, K. Nature