CATH Domain 2yx5A00

CATH Classification

Level	CATH Code	Description
	3	Alpha Beta
	3.30	2-Layer Sandwich
	3.30.1280	Mth169; Chain: A ,
	3.30.1280.10	Phosphoribosylformylglycinamidine synthase subunit PurS

Domain Context

CATH Clusters

Superfamily	Phosphoribosylformylglycinamidine synthase subunit PurS
Functional Family

Enzyme Information

6.3.5.3

Phosphoribosylformylglycinamidine synthase.

based on mapping to UniProt Q58988

ATP + N(2)-formyl-N(1)-(5-phospho-D-ribosyl)glycinamide + L-glutamine + H(2)O = ADP + phosphate + 2-(formamido)-N(1)-(5-phospho-D- ribosyl)acetamidine + L-glutamate.

UniProtKB Entries (1)

Q58988

PURS_METJA

Methanocaldococcus jannaschii DSM 2661

Phosphoribosylformylglycinamidine synthase subunit PurS

PDB Structure

PDB	2YX5
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism	Escherichia
Primary Citation	Crystal Structure of Methanocaldococcus jannaschii PurS, One of the Subunits of Formylglycinamide Ribonucleotide Amidotransferase in the Purine Biosynthetic Pathway Kanagawa, M., Baba, S., Agari, Y., Chen, L.Q., Fu, Z.-Q., Chrzas, J., Wang, B.C., Kuramitsu, S., Yokoyama, S., Kawai, G., Sampei, G. To be Published