CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
1 | Mainly Alpha |
|
1.10 | Orthogonal Bundle |
|
1.10.437 | Apoptosis Regulator Bcl-x |
|
1.10.437.10 | Blc2-like |
Domain Context
CATH Clusters
| Superfamily | Blc2-like |
| Functional Family | Apoptosis regulator Bcl-2 |
Enzyme Information
UniProtKB Entries (1)
| P10415 |
BCL2_HUMAN
Homo sapiens
Apoptosis regulator Bcl-2
|
PDB Structure
| PDB | 2W3L |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
Tetrahydroisoquinoline Amide Substituted Phenyl Pyrazoles as Selective Bcl-2 Inhibitors.
Bioorg.Med.Chem.Lett.
|
