CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.50 | 3-Layer(bba) Sandwich |
|
3.50.4 | Hepatocyte Growth Factor |
|
3.50.4.10 | Hepatocyte Growth Factor |
Domain Context
CATH Clusters
| Superfamily | Hepatocyte Growth Factor |
| Functional Family | Coagulation factor XI |
Enzyme Information
| 3.4.21.27 |
Coagulation factor XIa.
based on mapping to UniProt P03951
Selective cleavage of Arg-|-Ala and Arg-|-Val bonds in factor IX to form factor IXa.
-!- The proenzyme XI is activated by EC 3.4.21.38. -!- Belongs to peptidase family S1.
|
UniProtKB Entries (1)
| P03951 |
FA11_HUMAN
Homo sapiens
Coagulation factor XI
|
PDB Structure
| PDB | 2J8J |
| External Links | |
| Method | SOLUTION NMR |
| Organism | |
| Primary Citation |
Solution Structure of the A4 Domain of Factor Xi Sheds Light on the Mechanism of Zymogen Activation.
Proc.Natl.Acad.Sci.USA
|
