CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.30 | 2-Layer Sandwich |
|
3.30.2350 | Pseudouridine synthase |
|
3.30.2350.20 | TruD, catalytic domain |
Domain Context
CATH Clusters
| Superfamily | TruD, catalytic domain |
| Functional Family | Probable tRNA pseudouridine synthase D |
Enzyme Information
| 5.4.99.27 |
tRNA pseudouridine(13) synthase.
based on mapping to UniProt Q8Q0M2
tRNA uridine(13) = tRNA pseudouridine(13).
-!- Pseudouridine synthase PusS from Escherichia coli specifically acts on uridine(13) in tRNA. -!- The Pus7 protein from Saccharomyces cerevisiae is a multisite- multisubstrate pseudouridine synthase that is able to modify uridine(13) in several yeast tRNAs, uridine(35) in the pre-tRNA(Tyr), uridine(35) in U2 small nuclear RNA, and uridine(50) in 5S rRNA.
|
UniProtKB Entries (1)
| Q8Q0M2 |
TRUD_METMA
Methanosarcina mazei Go1
Probable tRNA pseudouridine synthase D
|
PDB Structure
| PDB | 1Z2Z |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | Escherichia |
| Primary Citation |
Crystal Structure of the Putative tRNA pseudouridine synthase D (TruD) from Methanosarcina mazei, Northeast Structural Genomics Target MaR1
To be Published
|
