CATH Domain 1qsaA02

CATH Classification

Level	CATH Code	Description
	1	Mainly Alpha
	1.10	Orthogonal Bundle
	1.10.1240	Methyltransferase, Methionine Synthase (B12-binding Domains); Chain A, domain 1
	1.10.1240.20	Lytic transglycosylase, superhelical linker domain

Domain Context

CATH Clusters

Superfamily	Lytic transglycosylase, superhelical linker domain
Functional Family	Soluble lytic murein transglycosylase

Enzyme Information

4.2.2.n1

Peptidoglycan lytic exotransglycosylase.

based on mapping to UniProt P0AGC3

Exolytic cleavage of the (1->4)-beta-glycosidic linkage between N-acetylmuramic acid (MurNAc) and N-acetylglucosamine (GlcNAc) residues in peptidoglycan, from either the reducing or the non-reducing ends of the peptidoglycan chains, with concomitant formation of a 1,6-anhydrobond in the MurNAc residue.

UniProtKB Entries (1)

P0AGC3

SLT_ECOLI

Escherichia coli K-12

Soluble lytic murein transglycosylase

PDB Structure

PDB	1QSA
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism	Escherichia
Primary Citation	High resolution crystal structures of the Escherichia coli lytic transglycosylase Slt70 and its complex with a peptidoglycan fragment. van Asselt, E.J., Thunnissen, A.M., Dijkstra, B.W. J.Mol.Biol.