CATH Domain 1o77E00

CATH Classification

Level	CATH Code	Description
	3	Alpha Beta
	3.40	3-Layer(aba) Sandwich
	3.40.50	Rossmann fold
	3.40.50.10140	Toll/interleukin-1 receptor homology (TIR) domain

Domain Context

CATH Clusters

Superfamily	Toll/interleukin-1 receptor homology (TIR) domain
Functional Family	Toll-like receptor 2

Enzyme Information

UniProtKB Entries (1)

TLR2_HUMAN

Homo sapiens

Toll-like receptor 2

PDB Structure

PDB	1O77
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	An Extensively Associated Dimer in the Structure of the C713S Mutant of the Tir Domain of Human Tlr2 Tao, X., Xu, Y., Zheng, Y., Beg, A.A., Tong, L. Biochem.Biophys.Res.Commun.