CATH Domain 1o6eB00

CATH Classification

Level	CATH Code	Description
	3	Alpha Beta
	3.20	Alpha-Beta Barrel
	3.20.16	Serine Protease, Human Cytomegalovirus Protease; Chain A
	3.20.16.10	Herpesvirus/Caudovirus protease domain

Domain Context

CATH Clusters

Superfamily	Herpesvirus/Caudovirus protease domain
Functional Family

Enzyme Information

3.4.21.97

Assemblin.

based on mapping to UniProt P03234

Cleaves -Ala-|-Ser- and -Ala-|-Ala- bonds in the scaffold protein.

-!- Involved in the breakdown of the scaffold protein during the late stages of assembly of the herpes-virus virion. -!- Inhibited by diisopropyl fluorophosphate. -!- Belongs to peptidase family S21.

UniProtKB Entries (1)

P03234

SCAF_EBVB9

Human herpesvirus 4 strain B95-8

Capsid scaffolding protein

PDB Structure

PDB	1O6E
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	The Crystal Structure of the Epstein-Barr Virus Protease Shows Rearrangement of the Processed C Terminus Buisson, M., Hernandez, J., Lascoux, D., Schoehn, G., Forest, E., Arlaud, G., Seigneurin, J., Ruigrok, R.W.H., Burmeister, W.P. J.Mol.Biol.