The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
TCF3-CBD (Catenin binding domain)
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 4: lymphoid enhancer-binding factor 1 isoform X2

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 55 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
DNA binding GO:0003677
Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid).
8 O93345 (/ISS) Q56R97 (/ISS) Q56R97 (/ISS) Q5R2J3 (/ISS) Q9QXN1 (/ISS) Q9UJU2 (/ISS) Q9UJU2 (/ISS) Q9W7C0 (/ISS)
DNA binding, bending GO:0008301
The activity of binding selectively and non-covalently to and distorting the original structure of DNA, typically a straight helix, into a bend, or increasing the bend if the original structure was intrinsically bent due to its sequence.
8 O93345 (/ISS) Q56R97 (/ISS) Q56R97 (/ISS) Q5R2J3 (/ISS) Q9QXN1 (/ISS) Q9UJU2 (/ISS) Q9UJU2 (/ISS) Q9W7C0 (/ISS)
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
5 P27782 (/IPI) P27782 (/IPI) Q9QXN1 (/IPI) Q9UJU2 (/IPI) Q9UJU2 (/IPI)
RNA polymerase II proximal promoter sequence-specific DNA binding GO:0000978
Interacting selectively and non-covalently with a specific upstream regulatory DNA sequence (transcription factor recognition sequence or binding site) located in the proximal promoter of a gene transcribed by RNA polymerase II. The proximal promoter is in cis with and relatively close to the core promoter.
4 O93345 (/ISS) Q5R2J3 (/ISS) Q9UJU2 (/ISS) Q9UJU2 (/ISS)
DNA-binding transcription factor activity GO:0003700
A protein or a member of a complex that interacts selectively and non-covalently with a specific DNA sequence (sometimes referred to as a motif) within the regulatory region of a gene to modulate transcription. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units, and include bacterial operons.
4 P27782 (/IDA) P27782 (/IDA) Q9UJU2 (/IDA) Q9UJU2 (/IDA)
Sequence-specific DNA binding GO:0043565
Interacting selectively and non-covalently with DNA of a specific nucleotide composition, e.g. GC-rich DNA binding, or with a specific sequence motif or type of DNA e.g. promotor binding or rDNA binding.
4 P27782 (/IDA) P27782 (/IDA) Q9UJU2 (/IDA) Q9UJU2 (/IDA)
Transcription regulatory region DNA binding GO:0044212
Interacting selectively and non-covalently with a DNA region that regulates the transcription of a region of DNA, which may be a gene, cistron, or operon. Binding may occur as a sequence specific interaction or as an interaction observed only once a factor has been recruited to the DNA by other factors.
4 P27782 (/IDA) P27782 (/IDA) Q9UJU2 (/IDA) Q9UJU2 (/IDA)
RNA polymerase II regulatory region sequence-specific DNA binding GO:0000977
Interacting selectively and non-covalently with a specific sequence of DNA that is part of a regulatory region that controls the transcription of a gene or cistron by RNA polymerase II.
2 Q9UJU2 (/IDA) Q9UJU2 (/IDA)
RNA polymerase II regulatory region sequence-specific DNA binding GO:0000977
Interacting selectively and non-covalently with a specific sequence of DNA that is part of a regulatory region that controls the transcription of a gene or cistron by RNA polymerase II.
2 P27782 (/ISO) P27782 (/ISO)
RNA polymerase II proximal promoter sequence-specific DNA binding GO:0000978
Interacting selectively and non-covalently with a specific upstream regulatory DNA sequence (transcription factor recognition sequence or binding site) located in the proximal promoter of a gene transcribed by RNA polymerase II. The proximal promoter is in cis with and relatively close to the core promoter.
2 P27782 (/IDA) P27782 (/IDA)
DNA-binding transcription factor activity, RNA polymerase II-specific GO:0000981
A protein or a member of a complex that interacts selectively and non-covalently with a specific DNA sequence (sometimes referred to as a motif) within the regulatory region of a RNA polymerase II-transcribed gene to modulate transcription. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units.
2 P27782 (/IGI) P27782 (/IGI)
DNA-binding transcription factor activity, RNA polymerase II-specific GO:0000981
A protein or a member of a complex that interacts selectively and non-covalently with a specific DNA sequence (sometimes referred to as a motif) within the regulatory region of a RNA polymerase II-transcribed gene to modulate transcription. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units.
2 Q9UJU2 (/ISA) Q9UJU2 (/ISA)
DNA-binding transcription factor activity, RNA polymerase II-specific GO:0000981
A protein or a member of a complex that interacts selectively and non-covalently with a specific DNA sequence (sometimes referred to as a motif) within the regulatory region of a RNA polymerase II-transcribed gene to modulate transcription. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units.
2 Q9UJU2 (/ISM) Q9UJU2 (/ISM)
DNA-binding transcription factor activity, RNA polymerase II-specific GO:0000981
A protein or a member of a complex that interacts selectively and non-covalently with a specific DNA sequence (sometimes referred to as a motif) within the regulatory region of a RNA polymerase II-transcribed gene to modulate transcription. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units.
2 O93345 (/ISS) Q5R2J3 (/ISS)
DNA-binding transcription factor activity, RNA polymerase II-specific GO:0000981
A protein or a member of a complex that interacts selectively and non-covalently with a specific DNA sequence (sometimes referred to as a motif) within the regulatory region of a RNA polymerase II-transcribed gene to modulate transcription. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units.
2 Q9UJU2 (/NAS) Q9UJU2 (/NAS)
DNA-binding transcription factor activity, RNA polymerase II-specific GO:0000981
A protein or a member of a complex that interacts selectively and non-covalently with a specific DNA sequence (sometimes referred to as a motif) within the regulatory region of a RNA polymerase II-transcribed gene to modulate transcription. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units.
2 A0A0R4II86 (/TAS) Q9W7C0 (/TAS)
DNA-binding transcription activator activity, RNA polymerase II-specific GO:0001228
A protein or a member of a complex that interacts selectively and non-covalently with a specific DNA sequence (sometimes referred to as a motif) within the regulatory region of a RNA polymerase II-transcribed gene to activate or increase transcription. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units.
2 P27782 (/IDA) P27782 (/IDA)
DNA-binding transcription activator activity, RNA polymerase II-specific GO:0001228
A protein or a member of a complex that interacts selectively and non-covalently with a specific DNA sequence (sometimes referred to as a motif) within the regulatory region of a RNA polymerase II-transcribed gene to activate or increase transcription. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units.
2 Q9UJU2 (/IMP) Q9UJU2 (/IMP)
DNA-binding transcription activator activity, RNA polymerase II-specific GO:0001228
A protein or a member of a complex that interacts selectively and non-covalently with a specific DNA sequence (sometimes referred to as a motif) within the regulatory region of a RNA polymerase II-transcribed gene to activate or increase transcription. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units.
2 P27782 (/ISO) P27782 (/ISO)
DNA-binding transcription activator activity, RNA polymerase II-specific GO:0001228
A protein or a member of a complex that interacts selectively and non-covalently with a specific DNA sequence (sometimes referred to as a motif) within the regulatory region of a RNA polymerase II-transcribed gene to activate or increase transcription. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units.
2 O93345 (/ISS) Q5R2J3 (/ISS)
DNA binding GO:0003677
Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid).
2 P27782 (/IDA) P27782 (/IDA)
Chromatin binding GO:0003682
Interacting selectively and non-covalently with chromatin, the network of fibers of DNA, protein, and sometimes RNA, that make up the chromosomes of the eukaryotic nucleus during interphase.
2 P27782 (/IDA) P27782 (/IDA)
Chromatin binding GO:0003682
Interacting selectively and non-covalently with chromatin, the network of fibers of DNA, protein, and sometimes RNA, that make up the chromosomes of the eukaryotic nucleus during interphase.
2 O93345 (/ISS) Q5R2J3 (/ISS)
DNA-binding transcription factor activity GO:0003700
A protein or a member of a complex that interacts selectively and non-covalently with a specific DNA sequence (sometimes referred to as a motif) within the regulatory region of a gene to modulate transcription. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units, and include bacterial operons.
2 P27782 (/ISO) P27782 (/ISO)
DNA-binding transcription factor activity GO:0003700
A protein or a member of a complex that interacts selectively and non-covalently with a specific DNA sequence (sometimes referred to as a motif) within the regulatory region of a gene to modulate transcription. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units, and include bacterial operons.
2 O93345 (/ISS) Q5R2J3 (/ISS)
Beta-catenin binding GO:0008013
Interacting selectively and non-covalently with the beta subunit of the catenin complex.
2 Q9UJU2 (/IDA) Q9UJU2 (/IDA)
Beta-catenin binding GO:0008013
Interacting selectively and non-covalently with the beta subunit of the catenin complex.
2 Q9UJU2 (/IPI) Q9UJU2 (/IPI)
Beta-catenin binding GO:0008013
Interacting selectively and non-covalently with the beta subunit of the catenin complex.
2 P27782 (/ISO) P27782 (/ISO)
Beta-catenin binding GO:0008013
Interacting selectively and non-covalently with the beta subunit of the catenin complex.
2 Q9UJU2 (/TAS) Q9UJU2 (/TAS)
Transcription factor binding GO:0008134
Interacting selectively and non-covalently with a transcription factor, a protein required to initiate or regulate transcription.
2 P27782 (/IPI) P27782 (/IPI)
Transcription factor binding GO:0008134
Interacting selectively and non-covalently with a transcription factor, a protein required to initiate or regulate transcription.
2 O93345 (/ISS) Q5R2J3 (/ISS)
DNA binding, bending GO:0008301
The activity of binding selectively and non-covalently to and distorting the original structure of DNA, typically a straight helix, into a bend, or increasing the bend if the original structure was intrinsically bent due to its sequence.
2 P27782 (/IDA) P27782 (/IDA)
Estrogen receptor activity GO:0030284
Combining with estrogen and transmitting the signal within the cell to trigger a change in cell activity or function.
2 Q9UJU2 (/IDA) Q9UJU2 (/IDA)
Estrogen receptor activity GO:0030284
Combining with estrogen and transmitting the signal within the cell to trigger a change in cell activity or function.
2 P27782 (/ISO) P27782 (/ISO)
Estrogen receptor binding GO:0030331
Interacting selectively and non-covalently with an estrogen receptor.
2 Q9UJU2 (/IDA) Q9UJU2 (/IDA)
Estrogen receptor binding GO:0030331
Interacting selectively and non-covalently with an estrogen receptor.
2 P27782 (/ISO) P27782 (/ISO)
Enhancer binding GO:0035326
Interacting selectively and non-covalently with an enhancer, a transcription regulatory region that is somewhat distal from the core promoter and which enhances transcription from that promoter.
2 Q9UJU2 (/IDA) Q9UJU2 (/IDA)
Enhancer binding GO:0035326
Interacting selectively and non-covalently with an enhancer, a transcription regulatory region that is somewhat distal from the core promoter and which enhances transcription from that promoter.
2 P27782 (/ISO) P27782 (/ISO)
Histone binding GO:0042393
Interacting selectively and non-covalently with a histone, any of a group of water-soluble proteins found in association with the DNA of eukaroytic chromosomes. They are involved in the condensation and coiling of chromosomes during cell division and have also been implicated in nonspecific suppression of gene activity.
2 Q9UJU2 (/IPI) Q9UJU2 (/IPI)
Histone binding GO:0042393
Interacting selectively and non-covalently with a histone, any of a group of water-soluble proteins found in association with the DNA of eukaroytic chromosomes. They are involved in the condensation and coiling of chromosomes during cell division and have also been implicated in nonspecific suppression of gene activity.
2 P27782 (/ISO) P27782 (/ISO)
Histone deacetylase binding GO:0042826
Interacting selectively and non-covalently with the enzyme histone deacetylase.
2 Q9UJU2 (/IPI) Q9UJU2 (/IPI)
Histone deacetylase binding GO:0042826
Interacting selectively and non-covalently with the enzyme histone deacetylase.
2 P27782 (/ISO) P27782 (/ISO)
Cysteine-type endopeptidase inhibitor activity involved in apoptotic process GO:0043027
Stops, prevents or reduces the activity of a cysteine-type endopeptidase involved in the apoptotic process.
2 Q9UJU2 (/IMP) Q9UJU2 (/IMP)
Cysteine-type endopeptidase inhibitor activity involved in apoptotic process GO:0043027
Stops, prevents or reduces the activity of a cysteine-type endopeptidase involved in the apoptotic process.
2 P27782 (/ISO) P27782 (/ISO)
Sequence-specific DNA binding GO:0043565
Interacting selectively and non-covalently with DNA of a specific nucleotide composition, e.g. GC-rich DNA binding, or with a specific sequence motif or type of DNA e.g. promotor binding or rDNA binding.
2 A0A0R4II86 (/IPI) Q9W7C0 (/IPI)
Sequence-specific DNA binding GO:0043565
Interacting selectively and non-covalently with DNA of a specific nucleotide composition, e.g. GC-rich DNA binding, or with a specific sequence motif or type of DNA e.g. promotor binding or rDNA binding.
2 P27782 (/ISO) P27782 (/ISO)
Sequence-specific DNA binding GO:0043565
Interacting selectively and non-covalently with DNA of a specific nucleotide composition, e.g. GC-rich DNA binding, or with a specific sequence motif or type of DNA e.g. promotor binding or rDNA binding.
2 O93345 (/ISS) Q5R2J3 (/ISS)
Transcription regulatory region DNA binding GO:0044212
Interacting selectively and non-covalently with a DNA region that regulates the transcription of a region of DNA, which may be a gene, cistron, or operon. Binding may occur as a sequence specific interaction or as an interaction observed only once a factor has been recruited to the DNA by other factors.
2 P27782 (/ISO) P27782 (/ISO)
Transcription regulatory region DNA binding GO:0044212
Interacting selectively and non-covalently with a DNA region that regulates the transcription of a region of DNA, which may be a gene, cistron, or operon. Binding may occur as a sequence specific interaction or as an interaction observed only once a factor has been recruited to the DNA by other factors.
2 O93345 (/ISS) Q5R2J3 (/ISS)
Gamma-catenin binding GO:0045295
Interacting selectively and non-covalently with the gamma subunit of the catenin complex.
2 Q9UJU2 (/IPI) Q9UJU2 (/IPI)
Gamma-catenin binding GO:0045295
Interacting selectively and non-covalently with the gamma subunit of the catenin complex.
2 P27782 (/ISO) P27782 (/ISO)
Armadillo repeat domain binding GO:0070016
Interacting selectively and non-covalently with the armadillo repeat domain of a protein, an approximately 40 amino acid long tandemly repeated sequence motif first identified in the Drosophila segment polarity protein armadillo. Arm-repeat proteins are involved in various processes, including intracellular signalling and cytoskeletal regulation.
2 Q9UJU2 (/IPI) Q9UJU2 (/IPI)
Armadillo repeat domain binding GO:0070016
Interacting selectively and non-covalently with the armadillo repeat domain of a protein, an approximately 40 amino acid long tandemly repeated sequence motif first identified in the Drosophila segment polarity protein armadillo. Arm-repeat proteins are involved in various processes, including intracellular signalling and cytoskeletal regulation.
2 P27782 (/ISO) P27782 (/ISO)
C2H2 zinc finger domain binding GO:0070742
Interacting selectively and non-covalently with a C2H2-type zinc finger domain of a protein. The C2H2 zinc finger is the classical zinc finger domain, in which two conserved cysteines and histidines co-ordinate a zinc ion.
2 Q9UJU2 (/IPI) Q9UJU2 (/IPI)
C2H2 zinc finger domain binding GO:0070742
Interacting selectively and non-covalently with a C2H2-type zinc finger domain of a protein. The C2H2 zinc finger is the classical zinc finger domain, in which two conserved cysteines and histidines co-ordinate a zinc ion.
2 P27782 (/ISO) P27782 (/ISO)

There are 176 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Positive regulation of transcription, DNA-templated GO:0045893
Any process that activates or increases the frequency, rate or extent of cellular DNA-templated transcription.
5 O93345 (/IMP) P27782 (/IMP) P27782 (/IMP) Q9UJU2 (/IMP) Q9UJU2 (/IMP)
Canonical Wnt signaling pathway GO:0060070
The series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell, followed by propagation of the signal via beta-catenin, and ending with a change in transcription of target genes. In this pathway, the activated receptor signals via downstream effectors that result in the inhibition of beta-catenin phosphorylation, thereby preventing degradation of beta-catenin. Stabilized beta-catenin can then accumulate and travel to the nucleus to trigger changes in transcription of target genes.
5 O93345 (/IDA) P27782 (/IDA) P27782 (/IDA) Q9UJU2 (/IDA) Q9UJU2 (/IDA)
Somitogenesis GO:0001756
The formation of mesodermal clusters that are arranged segmentally along the anterior posterior axis of an embryo.
4 A0A0R4II86 (/IMP) P27782 (/IMP) P27782 (/IMP) Q9W7C0 (/IMP)
Epithelial to mesenchymal transition GO:0001837
A transition where an epithelial cell loses apical/basolateral polarity, severs intercellular adhesive junctions, degrades basement membrane components and becomes a migratory mesenchymal cell.
4 O93345 (/ISS) Q5R2J3 (/ISS) Q9UJU2 (/ISS) Q9UJU2 (/ISS)
T-helper 1 cell differentiation GO:0045063
The process in which a relatively unspecialized T cell acquires the specialized features of a T-helper 1 (Th1) cell. A Th1 cell is a CD4-positive, alpha-beta T cell that has the phenotype T-bet-positive and produces interferon-gamma.
4 O93345 (/ISS) Q5R2J3 (/ISS) Q9UJU2 (/ISS) Q9UJU2 (/ISS)
Negative regulation of transcription, DNA-templated GO:0045892
Any process that stops, prevents, or reduces the frequency, rate or extent of cellular DNA-templated transcription.
4 P27782 (/IDA) P27782 (/IDA) Q9UJU2 (/IDA) Q9UJU2 (/IDA)
Positive regulation of transcription, DNA-templated GO:0045893
Any process that activates or increases the frequency, rate or extent of cellular DNA-templated transcription.
4 P27782 (/IDA) P27782 (/IDA) Q9UJU2 (/IDA) Q9UJU2 (/IDA)
Positive regulation of transcription by RNA polymerase II GO:0045944
Any process that activates or increases the frequency, rate or extent of transcription from an RNA polymerase II promoter.
4 P27782 (/IDA) P27782 (/IDA) Q9UJU2 (/IDA) Q9UJU2 (/IDA)
Positive regulation of transcription by RNA polymerase II GO:0045944
Any process that activates or increases the frequency, rate or extent of transcription from an RNA polymerase II promoter.
4 P27782 (/IMP) P27782 (/IMP) Q9UJU2 (/IMP) Q9UJU2 (/IMP)
Positive regulation of transcription by RNA polymerase II GO:0045944
Any process that activates or increases the frequency, rate or extent of transcription from an RNA polymerase II promoter.
4 O93345 (/ISS) Q5R2J3 (/ISS) Q9UJU2 (/ISS) Q9UJU2 (/ISS)
Canonical Wnt signaling pathway GO:0060070
The series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell, followed by propagation of the signal via beta-catenin, and ending with a change in transcription of target genes. In this pathway, the activated receptor signals via downstream effectors that result in the inhibition of beta-catenin phosphorylation, thereby preventing degradation of beta-catenin. Stabilized beta-catenin can then accumulate and travel to the nucleus to trigger changes in transcription of target genes.
4 A0A0R4II86 (/IGI) P27782 (/IGI) P27782 (/IGI) Q9W7C0 (/IGI)
Canonical Wnt signaling pathway GO:0060070
The series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell, followed by propagation of the signal via beta-catenin, and ending with a change in transcription of target genes. In this pathway, the activated receptor signals via downstream effectors that result in the inhibition of beta-catenin phosphorylation, thereby preventing degradation of beta-catenin. Stabilized beta-catenin can then accumulate and travel to the nucleus to trigger changes in transcription of target genes.
4 A0A0R4II86 (/IMP) P27782 (/IMP) P27782 (/IMP) Q9W7C0 (/IMP)
Secondary palate development GO:0062009
The biological process whose specific outcome is the progression of the secondary palate from an initial condition to its mature state. This process begins with the formation of the structure and ends with the mature structure. The secondary palate is the part of the palate formed from the fusion of the two palatine shelves, extensions of the maxillary prominences.
3 O93345 (/ISS) Q9UJU2 (/ISS) Q9UJU2 (/ISS)
Negative regulation of transcription by RNA polymerase II GO:0000122
Any process that stops, prevents, or reduces the frequency, rate or extent of transcription mediated by RNA polymerase II.
2 P27782 (/IDA) P27782 (/IDA)
Negative regulation of transcription by RNA polymerase II GO:0000122
Any process that stops, prevents, or reduces the frequency, rate or extent of transcription mediated by RNA polymerase II.
2 O93345 (/ISS) Q5R2J3 (/ISS)
Branching involved in blood vessel morphogenesis GO:0001569
The process of coordinated growth and sprouting of blood vessels giving rise to the organized vascular system.
2 P27782 (/IMP) P27782 (/IMP)
Branching involved in blood vessel morphogenesis GO:0001569
The process of coordinated growth and sprouting of blood vessels giving rise to the organized vascular system.
2 O93345 (/ISS) Q5R2J3 (/ISS)
Osteoblast differentiation GO:0001649
The process whereby a relatively unspecialized cell acquires the specialized features of an osteoblast, a mesodermal or neural crest cell that gives rise to bone.
2 Q9UJU2 (/IEP) Q9UJU2 (/IEP)
Neural crest cell migration GO:0001755
The characteristic movement of cells from the dorsal ridge of the neural tube to a variety of locations in a vertebrate embryo.
2 A0A0R4II86 (/IMP) Q9W7C0 (/IMP)
Somitogenesis GO:0001756
The formation of mesodermal clusters that are arranged segmentally along the anterior posterior axis of an embryo.
2 P27782 (/IGI) P27782 (/IGI)
Somitogenesis GO:0001756
The formation of mesodermal clusters that are arranged segmentally along the anterior posterior axis of an embryo.
2 O93345 (/ISS) Q5R2J3 (/ISS)
Epithelial to mesenchymal transition GO:0001837
A transition where an epithelial cell loses apical/basolateral polarity, severs intercellular adhesive junctions, degrades basement membrane components and becomes a migratory mesenchymal cell.
2 P27782 (/IMP) P27782 (/IMP)
Vasculature development GO:0001944
The process whose specific outcome is the progression of the vasculature over time, from its formation to the mature structure. The vasculature is an interconnected tubular multi-tissue structure that contains fluid that is actively transported around the organism.
2 P27782 (/IMP) P27782 (/IMP)
Vasculature development GO:0001944
The process whose specific outcome is the progression of the vasculature over time, from its formation to the mature structure. The vasculature is an interconnected tubular multi-tissue structure that contains fluid that is actively transported around the organism.
2 O93345 (/ISS) Q5R2J3 (/ISS)
Sprouting angiogenesis GO:0002040
The extension of new blood vessels from existing vessels into avascular tissues, this process includes the specialization of endothelial cells into leading tip and stalk cells, proliferation and migration of the endothelial cells and cell adhesion resulting in angiogenic sprout fusion or lumen formation.
2 P27782 (/IMP) P27782 (/IMP)
Sprouting angiogenesis GO:0002040
The extension of new blood vessels from existing vessels into avascular tissues, this process includes the specialization of endothelial cells into leading tip and stalk cells, proliferation and migration of the endothelial cells and cell adhesion resulting in angiogenic sprout fusion or lumen formation.
2 O93345 (/ISS) Q5R2J3 (/ISS)
Regulation of transcription by RNA polymerase II GO:0006357
Any process that modulates the frequency, rate or extent of transcription mediated by RNA polymerase II.
2 P27782 (/IDA) P27782 (/IDA)
Regulation of transcription by RNA polymerase II GO:0006357
Any process that modulates the frequency, rate or extent of transcription mediated by RNA polymerase II.
2 A0A0R4II86 (/IGI) Q9W7C0 (/IGI)
Regulation of transcription by RNA polymerase II GO:0006357
Any process that modulates the frequency, rate or extent of transcription mediated by RNA polymerase II.
2 O93345 (/ISS) Q5R2J3 (/ISS)
Transcription by RNA polymerase II GO:0006366
The synthesis of RNA from a DNA template by RNA polymerase II (RNAP II), originating at an RNA polymerase II promoter. Includes transcription of messenger RNA (mRNA) and certain small nuclear RNAs (snRNAs).
2 Q9UJU2 (/IDA) Q9UJU2 (/IDA)
Transcription by RNA polymerase II GO:0006366
The synthesis of RNA from a DNA template by RNA polymerase II (RNAP II), originating at an RNA polymerase II promoter. Includes transcription of messenger RNA (mRNA) and certain small nuclear RNAs (snRNAs).
2 P27782 (/ISO) P27782 (/ISO)
Wnt signaling pathway, calcium modulating pathway GO:0007223
The series of molecular signals initiated by binding of a Wnt protein to a receptor on the surface of the target cell where activated receptors leads to an increase in intracellular calcium and activation of protein kinase C (PKC).
2 Q9UJU2 (/TAS) Q9UJU2 (/TAS)
Positive regulation of cell population proliferation GO:0008284
Any process that activates or increases the rate or extent of cell proliferation.
2 Q9UJU2 (/IDA) Q9UJU2 (/IDA)
Positive regulation of cell population proliferation GO:0008284
Any process that activates or increases the rate or extent of cell proliferation.
2 P27782 (/ISO) P27782 (/ISO)
Positive regulation of gene expression GO:0010628
Any process that increases the frequency, rate or extent of gene expression. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product or products (proteins or RNA). This includes the production of an RNA transcript as well as any processing to produce a mature RNA product or an mRNA or circRNA (for protein-coding genes) and the translation of that mRNA or circRNA into protein. Protein maturation is included when required to form an active form of a product from an inactive precursor form.
2 Q9UJU2 (/IDA) Q9UJU2 (/IDA)
Positive regulation of gene expression GO:0010628
Any process that increases the frequency, rate or extent of gene expression. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product or products (proteins or RNA). This includes the production of an RNA transcript as well as any processing to produce a mature RNA product or an mRNA or circRNA (for protein-coding genes) and the translation of that mRNA or circRNA into protein. Protein maturation is included when required to form an active form of a product from an inactive precursor form.
2 A0A0R4II86 (/IMP) Q9W7C0 (/IMP)
Positive regulation of gene expression GO:0010628
Any process that increases the frequency, rate or extent of gene expression. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product or products (proteins or RNA). This includes the production of an RNA transcript as well as any processing to produce a mature RNA product or an mRNA or circRNA (for protein-coding genes) and the translation of that mRNA or circRNA into protein. Protein maturation is included when required to form an active form of a product from an inactive precursor form.
2 P27782 (/ISO) P27782 (/ISO)
Positive regulation of epithelial to mesenchymal transition GO:0010718
Any process that increases the rate, frequency, or extent of epithelial to mesenchymal transition. Epithelial to mesenchymal transition is where an epithelial cell loses apical/basolateral polarity, severs intercellular adhesive junctions, degrades basement membrane components and becomes a migratory mesenchymal cell.
2 Q9UJU2 (/IMP) Q9UJU2 (/IMP)
Positive regulation of epithelial to mesenchymal transition GO:0010718
Any process that increases the rate, frequency, or extent of epithelial to mesenchymal transition. Epithelial to mesenchymal transition is where an epithelial cell loses apical/basolateral polarity, severs intercellular adhesive junctions, degrades basement membrane components and becomes a migratory mesenchymal cell.
2 P27782 (/ISO) P27782 (/ISO)
Wnt signaling pathway GO:0016055
The series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell and ending with a change in cell state.
2 O93345 (/ISS) Q5R2J3 (/ISS)
Dentate gyrus development GO:0021542
The process whose specific outcome is the progression of the dentate gyrus over time, from its formation to the mature structure. The dentate gyrus is one of two interlocking gyri of the hippocampus. It contains granule cells, which project to the pyramidal cells and interneurons of the CA3 region of the ammon gyrus.
2 P27782 (/IMP) P27782 (/IMP)
Dentate gyrus development GO:0021542
The process whose specific outcome is the progression of the dentate gyrus over time, from its formation to the mature structure. The dentate gyrus is one of two interlocking gyri of the hippocampus. It contains granule cells, which project to the pyramidal cells and interneurons of the CA3 region of the ammon gyrus.
2 O93345 (/ISS) Q5R2J3 (/ISS)
Hippocampus development GO:0021766
The progression of the hippocampus over time from its initial formation until its mature state.
2 P27782 (/IMP) P27782 (/IMP)
Hippocampus development GO:0021766
The progression of the hippocampus over time from its initial formation until its mature state.
2 O93345 (/ISS) Q5R2J3 (/ISS)
Hypothalamus development GO:0021854
The progression of the hypothalamus region of the forebrain, from its initial formation to its mature state.
2 A0A0R4II86 (/IMP) Q9W7C0 (/IMP)
Forebrain radial glial cell differentiation GO:0021861
The process in which neuroepithelial cells of the neural tube give rise to radial glial cells, specialized bipotential progenitors cells of the forebrain. Differentiation includes the processes involved in commitment of a cell to a specific fate.
2 P27782 (/IGI) P27782 (/IGI)
Forebrain radial glial cell differentiation GO:0021861
The process in which neuroepithelial cells of the neural tube give rise to radial glial cells, specialized bipotential progenitors cells of the forebrain. Differentiation includes the processes involved in commitment of a cell to a specific fate.
2 O93345 (/ISS) Q5R2J3 (/ISS)
Forebrain neuroblast division GO:0021873
The division of a neuroblast located in the forebrain. Neuroblast division gives rise to at least another neuroblast.
2 P27782 (/IGI) P27782 (/IGI)
Forebrain neuroblast division GO:0021873
The division of a neuroblast located in the forebrain. Neuroblast division gives rise to at least another neuroblast.
2 O93345 (/ISS) Q5R2J3 (/ISS)
Forebrain neuron differentiation GO:0021879
The process in which a relatively unspecialized cell acquires specialized features of a neuron that will reside in the forebrain.
2 A0A0R4II86 (/IMP) Q9W7C0 (/IMP)
Formation of radial glial scaffolds GO:0021943
The formation of scaffolds from a radial glial cell. The scaffolds are used as a substrate for the radial migration of cells.
2 P27782 (/IGI) P27782 (/IGI)
Formation of radial glial scaffolds GO:0021943
The formation of scaffolds from a radial glial cell. The scaffolds are used as a substrate for the radial migration of cells.
2 O93345 (/ISS) Q5R2J3 (/ISS)
Hypothalamus cell differentiation GO:0021979
The differentiation of cells that will contribute to the structure and function of the hypothalamus.
2 A0A0R4II86 (/IMP) Q9W7C0 (/IMP)
Neurogenesis GO:0022008
Generation of cells within the nervous system.
2 A0A0R4II86 (/IGI) Q9W7C0 (/IGI)
Regulation of cell-cell adhesion GO:0022407
Any process that modulates the frequency, rate or extent of attachment of a cell to another cell.
2 P27782 (/IMP) P27782 (/IMP)
Regulation of cell-cell adhesion GO:0022407
Any process that modulates the frequency, rate or extent of attachment of a cell to another cell.
2 O93345 (/ISS) Q5R2J3 (/ISS)
Negative regulation of cell-cell adhesion GO:0022408
Any process that stops, prevents or reduces the rate or extent of cell adhesion to another cell.
2 P27782 (/ISO) P27782 (/ISO)
Positive regulation of cell-cell adhesion GO:0022409
Any process that activates or increases the rate or extent of cell adhesion to another cell.
2 P27782 (/ISO) P27782 (/ISO)
Regulation of Wnt signaling pathway GO:0030111
Any process that modulates the frequency, rate or extent of the activity of the Wnt signal transduction pathway.
2 P27782 (/IGI) P27782 (/IGI)
Regulation of Wnt signaling pathway GO:0030111
Any process that modulates the frequency, rate or extent of the activity of the Wnt signal transduction pathway.
2 O93345 (/ISS) Q5R2J3 (/ISS)
Neutrophil differentiation GO:0030223
The process in which a myeloid precursor cell acquires the specialized features of a neutrophil.
2 Q9UJU2 (/IMP) Q9UJU2 (/IMP)
Neutrophil differentiation GO:0030223
The process in which a myeloid precursor cell acquires the specialized features of a neutrophil.
2 P27782 (/ISO) P27782 (/ISO)
Positive regulation of cell growth GO:0030307
Any process that activates or increases the frequency, rate, extent or direction of cell growth.
2 Q9UJU2 (/IMP) Q9UJU2 (/IMP)
Positive regulation of cell growth GO:0030307
Any process that activates or increases the frequency, rate, extent or direction of cell growth.
2 P27782 (/ISO) P27782 (/ISO)
Embryonic limb morphogenesis GO:0030326
The process, occurring in the embryo, by which the anatomical structures of the limb are generated and organized. A limb is an appendage of an animal used for locomotion or grasping.
2 P27782 (/IGI) P27782 (/IGI)
Embryonic limb morphogenesis GO:0030326
The process, occurring in the embryo, by which the anatomical structures of the limb are generated and organized. A limb is an appendage of an animal used for locomotion or grasping.
2 O93345 (/ISS) Q5R2J3 (/ISS)
Positive regulation of cell migration GO:0030335
Any process that activates or increases the frequency, rate or extent of cell migration.
2 Q9UJU2 (/IMP) Q9UJU2 (/IMP)
Positive regulation of cell migration GO:0030335
Any process that activates or increases the frequency, rate or extent of cell migration.
2 P27782 (/ISO) P27782 (/ISO)
BMP signaling pathway GO:0030509
A series of molecular signals initiated by the binding of a member of the BMP (bone morphogenetic protein) family to a receptor on the surface of a target cell, and ending with regulation of a downstream cellular process, e.g. transcription.
2 P27782 (/IDA) P27782 (/IDA)
BMP signaling pathway GO:0030509
A series of molecular signals initiated by the binding of a member of the BMP (bone morphogenetic protein) family to a receptor on the surface of a target cell, and ending with regulation of a downstream cellular process, e.g. transcription.
2 O93345 (/ISS) Q5R2J3 (/ISS)
Positive regulation of granulocyte differentiation GO:0030854
Any process that activates or increases the frequency, rate or extent of granulocyte differentiation.
2 Q9UJU2 (/IDA) Q9UJU2 (/IDA)
Positive regulation of granulocyte differentiation GO:0030854
Any process that activates or increases the frequency, rate or extent of granulocyte differentiation.
2 Q9UJU2 (/IMP) Q9UJU2 (/IMP)
Positive regulation of granulocyte differentiation GO:0030854
Any process that activates or increases the frequency, rate or extent of granulocyte differentiation.
2 P27782 (/ISO) P27782 (/ISO)
Mammary gland development GO:0030879
The process whose specific outcome is the progression of the mammary gland over time, from its formation to the mature structure. The mammary gland is a large compound sebaceous gland that in female mammals is modified to secrete milk. Its development starts with the formation of the mammary line and ends as the mature gland cycles between nursing and weaning stages.
2 P27782 (/IMP) P27782 (/IMP)
Fin regeneration GO:0031101
The regrowth of fin tissue following its loss or destruction.
2 A0A0R4II86 (/IMP) Q9W7C0 (/IMP)
Negative regulation of interleukin-13 production GO:0032696
Any process that stops, prevents, or reduces the frequency, rate, or extent of interleukin-13 production.
2 Q9UJU2 (/IDA) Q9UJU2 (/IDA)
Negative regulation of interleukin-13 production GO:0032696
Any process that stops, prevents, or reduces the frequency, rate, or extent of interleukin-13 production.
2 P27782 (/ISO) P27782 (/ISO)
Negative regulation of interleukin-4 production GO:0032713
Any process that stops, prevents, or reduces the frequency, rate, or extent of interleukin-4 production.
2 Q9UJU2 (/IDA) Q9UJU2 (/IDA)
Negative regulation of interleukin-4 production GO:0032713
Any process that stops, prevents, or reduces the frequency, rate, or extent of interleukin-4 production.
2 P27782 (/ISO) P27782 (/ISO)
Negative regulation of interleukin-5 production GO:0032714
Any process that stops, prevents, or reduces the frequency, rate, or extent of interleukin-5 production.
2 Q9UJU2 (/IDA) Q9UJU2 (/IDA)
Negative regulation of interleukin-5 production GO:0032714
Any process that stops, prevents, or reduces the frequency, rate, or extent of interleukin-5 production.
2 P27782 (/ISO) P27782 (/ISO)
T cell receptor V(D)J recombination GO:0033153
The process in which T cell receptor V, D, and J, or V and J gene segments, depending on the specific locus, are recombined within a single locus utilizing the conserved heptamer and nonomer recombination signal sequences (RSS).
2 P27782 (/IGI) P27782 (/IGI)
T cell receptor V(D)J recombination GO:0033153
The process in which T cell receptor V, D, and J, or V and J gene segments, depending on the specific locus, are recombined within a single locus utilizing the conserved heptamer and nonomer recombination signal sequences (RSS).
2 O93345 (/ISS) Q5R2J3 (/ISS)
Fin development GO:0033333
The process whose specific outcome is the progression of a fin over time, from its formation to the mature structure.
2 A0A0R4II86 (/IMP) Q9W7C0 (/IMP)
Fin morphogenesis GO:0033334
The process in which the anatomical structures of a fin are generated and organized.
2 A0A0R4II86 (/IMP) Q9W7C0 (/IMP)
Caudal fin development GO:0033336
The process whose specific outcome is the progression of the caudal fin over time, from its formation to the mature structure.
2 A0A0R4II86 (/IMP) Q9W7C0 (/IMP)
Pectoral fin development GO:0033339
The process whose specific outcome is the progression of the pectoral fin over time, from its formation to the mature structure.
2 A0A0R4II86 (/IMP) Q9W7C0 (/IMP)
B cell proliferation GO:0042100
The expansion of a B cell population by cell division. Follows B cell activation.
2 P27782 (/IMP) P27782 (/IMP)
B cell proliferation GO:0042100
The expansion of a B cell population by cell division. Follows B cell activation.
2 O93345 (/ISS) Q5R2J3 (/ISS)
Odontogenesis of dentin-containing tooth GO:0042475
The process whose specific outcome is the progression of a dentin-containing tooth over time, from its formation to the mature structure. A dentin-containing tooth is a hard, bony organ borne on the jaw or other bone of a vertebrate, and is composed mainly of dentin, a dense calcified substance, covered by a layer of enamel.
2 P27782 (/IGI) P27782 (/IGI)
Odontogenesis of dentin-containing tooth GO:0042475
The process whose specific outcome is the progression of a dentin-containing tooth over time, from its formation to the mature structure. A dentin-containing tooth is a hard, bony organ borne on the jaw or other bone of a vertebrate, and is composed mainly of dentin, a dense calcified substance, covered by a layer of enamel.
2 P27782 (/IMP) P27782 (/IMP)
Negative regulation of apoptotic process GO:0043066
Any process that stops, prevents, or reduces the frequency, rate or extent of cell death by apoptotic process.
2 Q9UJU2 (/IMP) Q9UJU2 (/IMP)
Negative regulation of apoptotic process GO:0043066
Any process that stops, prevents, or reduces the frequency, rate or extent of cell death by apoptotic process.
2 P27782 (/ISO) P27782 (/ISO)
Negative regulation of cysteine-type endopeptidase activity involved in apoptotic process GO:0043154
Any process that stops, prevents, or reduces the frequency, rate or extent of a cysteine-type endopeptidase activity involved in the apoptotic process.
2 Q9UJU2 (/IMP) Q9UJU2 (/IMP)
Negative regulation of cysteine-type endopeptidase activity involved in apoptotic process GO:0043154
Any process that stops, prevents, or reduces the frequency, rate or extent of a cysteine-type endopeptidase activity involved in the apoptotic process.
2 P27782 (/ISO) P27782 (/ISO)
Negative regulation of DNA binding GO:0043392
Any process that stops or reduces the frequency, rate or extent of DNA binding. DNA binding is any process in which a gene product interacts selectively with DNA (deoxyribonucleic acid).
2 Q9UJU2 (/IDA) Q9UJU2 (/IDA)
Negative regulation of DNA binding GO:0043392
Any process that stops or reduces the frequency, rate or extent of DNA binding. DNA binding is any process in which a gene product interacts selectively with DNA (deoxyribonucleic acid).
2 P27782 (/ISO) P27782 (/ISO)
Tongue development GO:0043586
The process whose specific outcome is the progression of the tongue over time, from its formation to the mature structure. The tongue is the movable, muscular organ on the floor of the mouth of most vertebrates, in many other mammals is the principal organ of taste, aids in the prehension of food, in swallowing, and in modifying the voice as in speech.
2 P27782 (/IMP) P27782 (/IMP)
Tongue development GO:0043586
The process whose specific outcome is the progression of the tongue over time, from its formation to the mature structure. The tongue is the movable, muscular organ on the floor of the mouth of most vertebrates, in many other mammals is the principal organ of taste, aids in the prehension of food, in swallowing, and in modifying the voice as in speech.
2 O93345 (/ISS) Q5R2J3 (/ISS)
Positive regulation by host of viral transcription GO:0043923
Any process in which a host organism activates or increases the frequency, rate or extent of viral transcription, the synthesis of either RNA on a template of DNA or DNA on a template of RNA.
2 Q9UJU2 (/IDA) Q9UJU2 (/IDA)
Positive regulation by host of viral transcription GO:0043923
Any process in which a host organism activates or increases the frequency, rate or extent of viral transcription, the synthesis of either RNA on a template of DNA or DNA on a template of RNA.
2 P27782 (/ISO) P27782 (/ISO)
Histone H3 acetylation GO:0043966
The modification of histone H3 by the addition of an acetyl group.
2 Q9UJU2 (/IMP) Q9UJU2 (/IMP)
Histone H3 acetylation GO:0043966
The modification of histone H3 by the addition of an acetyl group.
2 P27782 (/ISO) P27782 (/ISO)
Histone H4 acetylation GO:0043967
The modification of histone H4 by the addition of an acetyl group.
2 Q9UJU2 (/IMP) Q9UJU2 (/IMP)
Histone H4 acetylation GO:0043967
The modification of histone H4 by the addition of an acetyl group.
2 P27782 (/ISO) P27782 (/ISO)
T-helper 1 cell differentiation GO:0045063
The process in which a relatively unspecialized T cell acquires the specialized features of a T-helper 1 (Th1) cell. A Th1 cell is a CD4-positive, alpha-beta T cell that has the phenotype T-bet-positive and produces interferon-gamma.
2 P27782 (/IDA) P27782 (/IDA)
Negative regulation of striated muscle tissue development GO:0045843
Any process that stops, prevents, or reduces the frequency, rate or extent of striated muscle development.
2 P27782 (/IDA) P27782 (/IDA)
Negative regulation of striated muscle tissue development GO:0045843
Any process that stops, prevents, or reduces the frequency, rate or extent of striated muscle development.
2 O93345 (/ISS) Q5R2J3 (/ISS)
Negative regulation of transcription, DNA-templated GO:0045892
Any process that stops, prevents, or reduces the frequency, rate or extent of cellular DNA-templated transcription.
2 Q9UJU2 (/IMP) Q9UJU2 (/IMP)
Negative regulation of transcription, DNA-templated GO:0045892
Any process that stops, prevents, or reduces the frequency, rate or extent of cellular DNA-templated transcription.
2 P27782 (/ISO) P27782 (/ISO)
Negative regulation of transcription, DNA-templated GO:0045892
Any process that stops, prevents, or reduces the frequency, rate or extent of cellular DNA-templated transcription.
2 O93345 (/ISS) Q5R2J3 (/ISS)
Positive regulation of transcription, DNA-templated GO:0045893
Any process that activates or increases the frequency, rate or extent of cellular DNA-templated transcription.
2 P27782 (/ISO) P27782 (/ISO)
Positive regulation of transcription, DNA-templated GO:0045893
Any process that activates or increases the frequency, rate or extent of cellular DNA-templated transcription.
2 O93345 (/ISS) Q5R2J3 (/ISS)
Positive regulation of transcription by RNA polymerase II GO:0045944
Any process that activates or increases the frequency, rate or extent of transcription from an RNA polymerase II promoter.
2 P27782 (/IGI) P27782 (/IGI)
Positive regulation of transcription by RNA polymerase II GO:0045944
Any process that activates or increases the frequency, rate or extent of transcription from an RNA polymerase II promoter.
2 P27782 (/ISO) P27782 (/ISO)
Alpha-beta T cell differentiation GO:0046632
The process in which a precursor cell type acquires the specialized features of an alpha-beta T cell. An alpha-beta T cell is a T cell that expresses an alpha-beta T cell receptor complex.
2 P27782 (/IGI) P27782 (/IGI)
Alpha-beta T cell differentiation GO:0046632
The process in which a precursor cell type acquires the specialized features of an alpha-beta T cell. An alpha-beta T cell is a T cell that expresses an alpha-beta T cell receptor complex.
2 O93345 (/ISS) Q5R2J3 (/ISS)
Paraxial mesoderm formation GO:0048341
The process that gives rise to the paraxial mesoderm. This process pertains to the initial formation of the structure from unspecified parts.
2 P27782 (/IGI) P27782 (/IGI)
Paraxial mesoderm formation GO:0048341
The process that gives rise to the paraxial mesoderm. This process pertains to the initial formation of the structure from unspecified parts.
2 O93345 (/ISS) Q5R2J3 (/ISS)
Cell development GO:0048468
The process whose specific outcome is the progression of the cell over time, from its formation to the mature structure. Cell development does not include the steps involved in committing a cell to a specific fate.
2 P27782 (/IGI) P27782 (/IGI)
Cell development GO:0048468
The process whose specific outcome is the progression of the cell over time, from its formation to the mature structure. Cell development does not include the steps involved in committing a cell to a specific fate.
2 O93345 (/ISS) Q5R2J3 (/ISS)
Muscle fiber development GO:0048747
The process whose specific outcome is the progression of the muscle fiber over time, from its formation to the mature structure. In skeletal muscle, fibers are formed by the maturation of myotubes. They can be classed as slow, intermediate/fast or fast.
2 A0A0R4II86 (/IMP) Q9W7C0 (/IMP)
Posterior lateral line development GO:0048916
The process whose specific outcome is the progression of the posterior lateral line over time, from its formation to the mature structure. The posterior lateral line consists of small sensory patches (neuromasts) located superficially on the skin or just under the skin in fluid-filled canals on the body and trunk of all fishes and most amphibians. The posterior lateral line develops from cranial ectodermal placodes situated behind the ear.
2 A0A0R4II86 (/IMP) Q9W7C0 (/IMP)
Posterior lateral line neuromast development GO:0048919
The process whose specific outcome is the progression of the posterior lateral line neuromast over time, from its formation to the mature structure. The neuromast is the sensory receptor of the anterior lateral line system and is composed of a population of sensory hair cells, and nonsensory supporting cells and mantle cells. Neuromast are located superficially on the epithelium or in lateral line canals.
2 A0A0R4II86 (/IMP) Q9W7C0 (/IMP)
Posterior lateral line neuromast deposition GO:0048922
The process in which a migrating neuromast primordium deposits clusters of undifferentiated cells (proneuromasts) along its migratory path in the developing posterior lateral line.
2 A0A0R4II86 (/IMP) Q9W7C0 (/IMP)
Positive regulation of neurogenesis GO:0050769
Any process that activates or increases the frequency, rate or extent of neurogenesis, the generation of cells within the nervous system.
2 A0A0R4II86 (/IMP) Q9W7C0 (/IMP)
Sensory perception of taste GO:0050909
The series of events required for an organism to receive a gustatory stimulus, convert it to a molecular signal, and recognize and characterize the signal. Gustation involves the direct detection of chemical composition, usually through contact with chemoreceptor cells. This is a neurological process.
2 P27782 (/IMP) P27782 (/IMP)
Sensory perception of taste GO:0050909
The series of events required for an organism to receive a gustatory stimulus, convert it to a molecular signal, and recognize and characterize the signal. Gustation involves the direct detection of chemical composition, usually through contact with chemoreceptor cells. This is a neurological process.
2 O93345 (/ISS) Q5R2J3 (/ISS)
Roof of mouth development GO:0060021
The biological process whose specific outcome is the progression of the roof of the mouth from an initial condition to its mature state. This process begins with the formation of the structure and ends with the mature structure. The roof of the mouth is the partition that separates the nasal and oral cavities.
2 O93345 (/ISS) Q5R2J3 (/ISS)
Anatomical structure regression GO:0060033
The developmental process in which an anatomical stucture is destroyed as a part of its normal progression.
2 P27782 (/IMP) P27782 (/IMP)
Anatomical structure regression GO:0060033
The developmental process in which an anatomical stucture is destroyed as a part of its normal progression.
2 O93345 (/ISS) Q5R2J3 (/ISS)
Canonical Wnt signaling pathway GO:0060070
The series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell, followed by propagation of the signal via beta-catenin, and ending with a change in transcription of target genes. In this pathway, the activated receptor signals via downstream effectors that result in the inhibition of beta-catenin phosphorylation, thereby preventing degradation of beta-catenin. Stabilized beta-catenin can then accumulate and travel to the nucleus to trigger changes in transcription of target genes.
2 P27782 (/ISO) P27782 (/ISO)
Face morphogenesis GO:0060325
The process in which the anatomical structures of the face are generated and organized. The face is the ventral division of the head.
2 P27782 (/IGI) P27782 (/IGI)
Face morphogenesis GO:0060325
The process in which the anatomical structures of the face are generated and organized. The face is the ventral division of the head.
2 O93345 (/ISS) Q5R2J3 (/ISS)
Cell chemotaxis GO:0060326
The directed movement of a motile cell guided by a specific chemical concentration gradient. Movement may be towards a higher concentration (positive chemotaxis) or towards a lower concentration (negative chemotaxis).
2 Q9UJU2 (/IDA) Q9UJU2 (/IDA)
Cell chemotaxis GO:0060326
The directed movement of a motile cell guided by a specific chemical concentration gradient. Movement may be towards a higher concentration (positive chemotaxis) or towards a lower concentration (negative chemotaxis).
2 P27782 (/ISO) P27782 (/ISO)
Apoptotic process involved in morphogenesis GO:0060561
Any apoptotic process that contributes to the shaping of an anatomical structure.
2 P27782 (/IMP) P27782 (/IMP)
Apoptotic process involved in morphogenesis GO:0060561
Any apoptotic process that contributes to the shaping of an anatomical structure.
2 O93345 (/ISS) Q5R2J3 (/ISS)
Chorio-allantoic fusion GO:0060710
The cell-cell adhesion process in which the cells of the chorion fuse to the cells of the allantois.
2 P27782 (/IGI) P27782 (/IGI)
Regulation of cell proliferation involved in tissue homeostasis GO:0060784
Any process that modulates the frequency, rate or extent of cell proliferation resulting in the maintenance of a steady-state number of cells within a tissue.
2 A0A0R4II86 (/IMP) Q9W7C0 (/IMP)
Trachea gland development GO:0061153
The progression of a trachea gland over time, from its formation to the mature structure. Trachea glands are found under the mucus of the trachea and secrete mucus, and agents that help protect the lung from injury and infection.
2 P27782 (/IMP) P27782 (/IMP)
Trachea gland development GO:0061153
The progression of a trachea gland over time, from its formation to the mature structure. Trachea glands are found under the mucus of the trachea and secrete mucus, and agents that help protect the lung from injury and infection.
2 O93345 (/ISS) Q5R2J3 (/ISS)
Secondary palate development GO:0062009
The biological process whose specific outcome is the progression of the secondary palate from an initial condition to its mature state. This process begins with the formation of the structure and ends with the mature structure. The secondary palate is the part of the palate formed from the fusion of the two palatine shelves, extensions of the maxillary prominences.
2 P27782 (/IMP) P27782 (/IMP)
Cellular response to cytokine stimulus GO:0071345
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cytokine stimulus.
2 Q9UJU2 (/IMP) Q9UJU2 (/IMP)
Cellular response to cytokine stimulus GO:0071345
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cytokine stimulus.
2 P27782 (/ISO) P27782 (/ISO)
Cellular response to interleukin-4 GO:0071353
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interleukin-4 stimulus.
2 Q9UJU2 (/IDA) Q9UJU2 (/IDA)
Cellular response to interleukin-4 GO:0071353
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interleukin-4 stimulus.
2 P27782 (/ISO) P27782 (/ISO)
Positive regulation of cell proliferation in bone marrow GO:0071864
A process that activates or increases the frequency, rate or extent of cell proliferation in the bone marrow.
2 Q9UJU2 (/IMP) Q9UJU2 (/IMP)
Positive regulation of cell proliferation in bone marrow GO:0071864
A process that activates or increases the frequency, rate or extent of cell proliferation in the bone marrow.
2 P27782 (/ISO) P27782 (/ISO)
Negative regulation of apoptotic process in bone marrow cell GO:0071866
Any process that stops, prevents, or reduces the frequency, rate or extent of the occurrence or rate of cell death by apoptotic process in the bone marrow.
2 Q9UJU2 (/IMP) Q9UJU2 (/IMP)
Negative regulation of apoptotic process in bone marrow cell GO:0071866
Any process that stops, prevents, or reduces the frequency, rate or extent of the occurrence or rate of cell death by apoptotic process in the bone marrow.
2 P27782 (/ISO) P27782 (/ISO)
Odontoblast differentiation GO:0071895
The process in which a relatively unspecialized cell of neural crest origin acquires the specialized features of an odontoblast, a cell on the outer surface of the dental pulp whose biological function is the creation of dentin.
2 P27782 (/ISO) P27782 (/ISO)
Negative regulation of estrogen receptor binding GO:0071899
Any process that stops, prevents, or reduces the frequency, rate or extent of estrogen receptor binding, interacting selectively with an estrogen receptor.
2 Q9UJU2 (/IDA) Q9UJU2 (/IDA)
Negative regulation of estrogen receptor binding GO:0071899
Any process that stops, prevents, or reduces the frequency, rate or extent of estrogen receptor binding, interacting selectively with an estrogen receptor.
2 P27782 (/ISO) P27782 (/ISO)
Positive regulation of cell cycle process GO:0090068
Any process that increases the rate, frequency or extent of a cellular process that is involved in the progression of biochemical and morphological phases and events that occur in a cell during successive cell replication or nuclear replication events.
2 P27782 (/ISO) P27782 (/ISO)
Regulation of retinoic acid biosynthetic process GO:1900052
Any process that modulates the frequency, rate or extent of retinoic acid biosynthetic process.
2 A0A0R4II86 (/IGI) Q9W7C0 (/IGI)
Apoptotic process involved in blood vessel morphogenesis GO:1902262
Any apoptotic process that is involved in blood vessel morphogenesis.
2 P27782 (/IMP) P27782 (/IMP)
Apoptotic process involved in blood vessel morphogenesis GO:1902262
Any apoptotic process that is involved in blood vessel morphogenesis.
2 O93345 (/ISS) Q5R2J3 (/ISS)
Beta-catenin-TCF complex assembly GO:1904837
The aggregation, arrangement and bonding together of a set of components to form a beta-catenin-TCF complex.
2 Q9UJU2 (/TAS) Q9UJU2 (/TAS)
Kidney development GO:0001822
The process whose specific outcome is the progression of the kidney over time, from its formation to the mature structure. The kidney is an organ that filters the blood and/or excretes the end products of body metabolism in the form of urine.
1 Q9QXN1 (/IEP)
Cell adhesion GO:0007155
The attachment of a cell, either to another cell or to an underlying substrate such as the extracellular matrix, via cell adhesion molecules.
1 Q9QXN1 (/IEP)
Cell population proliferation GO:0008283
The multiplication or reproduction of cells, resulting in the expansion of a cell population.
1 O93345 (/IMP)
Dorsal/ventral pattern formation GO:0009953
The regionalization process in which the areas along the dorsal/ventral axis are established that will lead to differences in cell differentiation. The dorsal/ventral axis is defined by a line that runs orthogonal to both the anterior/posterior and left/right axes. The dorsal end is defined by the upper or back side of an organism. The ventral end is defined by the lower or front side of an organism.
1 O93345 (/IMP)
Response to lithium ion GO:0010226
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a lithium (Li+) ion stimulus.
1 Q9QXN1 (/IEP)
Response to organic cyclic compound GO:0014070
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an organic cyclic compound stimulus.
1 Q9QXN1 (/IEP)
Animal organ regeneration GO:0031100
The regrowth of a lost or destroyed animal organ.
1 Q9QXN1 (/IEP)
Limb morphogenesis GO:0035108
The process in which the anatomical structures of a limb are generated and organized. A limb is a paired appendage of a tetrapod used for locomotion or grasping.
1 O93345 (/IMP)
Limb morphogenesis GO:0035108
The process in which the anatomical structures of a limb are generated and organized. A limb is a paired appendage of a tetrapod used for locomotion or grasping.
1 O93345 (/NAS)
Odontogenesis of dentin-containing tooth GO:0042475
The process whose specific outcome is the progression of a dentin-containing tooth over time, from its formation to the mature structure. A dentin-containing tooth is a hard, bony organ borne on the jaw or other bone of a vertebrate, and is composed mainly of dentin, a dense calcified substance, covered by a layer of enamel.
1 Q5R2J3 (/ISS)
Skin development GO:0043588
The process whose specific outcome is the progression of the skin over time, from its formation to the mature structure. The skin is the external membranous integument of an animal. In vertebrates the skin generally consists of two layers, an outer nonsensitive and nonvascular epidermis (cuticle or skarfskin) composed of cells which are constantly growing and multiplying in the deeper, and being thrown off in the superficial layers, as well as an inner vascular dermis (cutis, corium or true skin) composed mostly of connective tissue.
1 Q9QXN1 (/IEP)
Negative regulation of neuron differentiation GO:0045665
Any process that stops, prevents, or reduces the frequency, rate or extent of neuron differentiation.
1 O93345 (/IMP)
Eye pigmentation GO:0048069
Establishment of a pattern of pigment in the eye of an organism.
1 O93345 (/IMP)
Canonical Wnt signaling pathway GO:0060070
The series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell, followed by propagation of the signal via beta-catenin, and ending with a change in transcription of target genes. In this pathway, the activated receptor signals via downstream effectors that result in the inhibition of beta-catenin phosphorylation, thereby preventing degradation of beta-catenin. Stabilized beta-catenin can then accumulate and travel to the nucleus to trigger changes in transcription of target genes.
1 O93345 (/NAS)
Iris morphogenesis GO:0061072
The process in which the iris is generated and organized. The iris is an anatomical structure in the eye whose opening forms the pupil. The iris is responsible for controlling the diameter and size of the pupil and the amount of light reaching the retina.
1 O93345 (/IMP)
Ciliary body morphogenesis GO:0061073
The process in which the ciliary body generated and organized. The ciliary body is the circumferential tissue inside the eye composed of the ciliary muscle and ciliary processes.
1 O93345 (/IMP)
Odontoblast differentiation GO:0071895
The process in which a relatively unspecialized cell of neural crest origin acquires the specialized features of an odontoblast, a cell on the outer surface of the dental pulp whose biological function is the creation of dentin.
1 Q9QXN1 (/IMP)

There are 17 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
6 O93345 (/IDA) P27782 (/IDA) P27782 (/IDA) Q9QXN1 (/IDA) Q9UJU2 (/IDA) Q9UJU2 (/IDA)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
5 O93345 (/IDA) P27782 (/IDA) P27782 (/IDA) Q9UJU2 (/IDA) Q9UJU2 (/IDA)
Nucleoplasm GO:0005654
That part of the nuclear content other than the chromosomes or the nucleolus.
3 Q9QXN1 (/TAS) Q9UJU2 (/TAS) Q9UJU2 (/TAS)
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
2 Q9UJU2 (/IC) Q9UJU2 (/IC)
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
2 P27782 (/ISO) P27782 (/ISO)
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
2 O93345 (/ISS) Q5R2J3 (/ISS)
Transcription factor complex GO:0005667
A protein complex that is capable of associating with DNA by direct binding, or via other DNA-binding proteins or complexes, and regulating transcription.
2 Q9UJU2 (/IDA) Q9UJU2 (/IDA)
Transcription factor complex GO:0005667
A protein complex that is capable of associating with DNA by direct binding, or via other DNA-binding proteins or complexes, and regulating transcription.
2 P27782 (/IPI) P27782 (/IPI)
Transcription factor complex GO:0005667
A protein complex that is capable of associating with DNA by direct binding, or via other DNA-binding proteins or complexes, and regulating transcription.
2 P27782 (/ISO) P27782 (/ISO)
Transcription factor complex GO:0005667
A protein complex that is capable of associating with DNA by direct binding, or via other DNA-binding proteins or complexes, and regulating transcription.
2 O93345 (/ISS) Q5R2J3 (/ISS)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
2 P27782 (/ISO) P27782 (/ISO)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
2 O93345 (/ISS) Q5R2J3 (/ISS)
Protein-DNA complex GO:0032993
A macromolecular complex containing both protein and DNA molecules.
2 Q9UJU2 (/IDA) Q9UJU2 (/IDA)
Protein-DNA complex GO:0032993
A macromolecular complex containing both protein and DNA molecules.
2 P27782 (/ISO) P27782 (/ISO)
Beta-catenin-TCF complex GO:1990907
A protein complex that contains beta-catenin and a member of the T-cell factor (TCF)/lymphoid enhancer binding factor (LEF) family of transcription factors.
2 P27782 (/IC) P27782 (/IC)
Beta-catenin-TCF complex GO:1990907
A protein complex that contains beta-catenin and a member of the T-cell factor (TCF)/lymphoid enhancer binding factor (LEF) family of transcription factors.
2 Q9UJU2 (/IPI) Q9UJU2 (/IPI)
Beta-catenin-TCF complex GO:1990907
A protein complex that contains beta-catenin and a member of the T-cell factor (TCF)/lymphoid enhancer binding factor (LEF) family of transcription factors.
2 P27782 (/ISO) P27782 (/ISO)