The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Agouti domain
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 1: Agouti-related protein

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 7 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Neuropeptide hormone activity GO:0005184
The action characteristic of a neuropeptide hormone, any peptide hormone that acts in the central nervous system. A neuropeptide is any of several types of molecules found in brain tissue, composed of short chains of amino acids; they include endorphins, enkephalins, vasopressin, and others. They are often localized in axon terminals at synapses and are classified as putative neurotransmitters, although some are also hormones.
6 O00253 (/IDA) O00253 (/IDA) O00253 (/IDA) O00253 (/IDA) P56473 (/IDA) P56473 (/IDA)
Neuropeptide hormone activity GO:0005184
The action characteristic of a neuropeptide hormone, any peptide hormone that acts in the central nervous system. A neuropeptide is any of several types of molecules found in brain tissue, composed of short chains of amino acids; they include endorphins, enkephalins, vasopressin, and others. They are often localized in axon terminals at synapses and are classified as putative neurotransmitters, although some are also hormones.
5 P56413 (/ISS) P56473 (/ISS) P56473 (/ISS) Q9TU18 (/ISS) Q9TU18 (/ISS)
Type 3 melanocortin receptor binding GO:0031781
Interacting selectively and non-covalently with a type 3 melanocortin receptor.
5 P56413 (/ISS) P56473 (/ISS) P56473 (/ISS) Q9TU18 (/ISS) Q9TU18 (/ISS)
Type 4 melanocortin receptor binding GO:0031782
Interacting selectively and non-covalently with a type 4 melanocortin receptor.
5 P56413 (/ISS) P56473 (/ISS) P56473 (/ISS) Q9TU18 (/ISS) Q9TU18 (/ISS)
Signaling receptor binding GO:0005102
Interacting selectively and non-covalently with one or more specific sites on a receptor molecule, a macromolecule that undergoes combination with a hormone, neurotransmitter, drug or intracellular messenger to initiate a change in cell function.
4 O00253 (/TAS) O00253 (/TAS) O00253 (/TAS) O00253 (/TAS)
Neuropeptide hormone activity GO:0005184
The action characteristic of a neuropeptide hormone, any peptide hormone that acts in the central nervous system. A neuropeptide is any of several types of molecules found in brain tissue, composed of short chains of amino acids; they include endorphins, enkephalins, vasopressin, and others. They are often localized in axon terminals at synapses and are classified as putative neurotransmitters, although some are also hormones.
4 O00253 (/TAS) O00253 (/TAS) O00253 (/TAS) O00253 (/TAS)
Neuropeptide hormone activity GO:0005184
The action characteristic of a neuropeptide hormone, any peptide hormone that acts in the central nervous system. A neuropeptide is any of several types of molecules found in brain tissue, composed of short chains of amino acids; they include endorphins, enkephalins, vasopressin, and others. They are often localized in axon terminals at synapses and are classified as putative neurotransmitters, although some are also hormones.
2 P56473 (/ISO) P56473 (/ISO)

There are 12 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Neuropeptide signaling pathway GO:0007218
The series of molecular signals generated as a consequence of a peptide neurotransmitter binding to a cell surface receptor.
6 O00253 (/IDA) O00253 (/IDA) O00253 (/IDA) O00253 (/IDA) P56473 (/IDA) P56473 (/IDA)
Neuropeptide signaling pathway GO:0007218
The series of molecular signals generated as a consequence of a peptide neurotransmitter binding to a cell surface receptor.
5 P56413 (/ISS) P56473 (/ISS) P56473 (/ISS) Q9TU18 (/ISS) Q9TU18 (/ISS)
Regulation of feeding behavior GO:0060259
Any process that modulates the rate, frequency or extent of the behavior associated with the intake of food.
5 P56413 (/ISS) P56473 (/ISS) P56473 (/ISS) Q9TU18 (/ISS) Q9TU18 (/ISS)
Neuropeptide signaling pathway GO:0007218
The series of molecular signals generated as a consequence of a peptide neurotransmitter binding to a cell surface receptor.
4 O00253 (/TAS) O00253 (/TAS) O00253 (/TAS) O00253 (/TAS)
Feeding behavior GO:0007631
Behavior associated with the intake of food.
4 O00253 (/TAS) O00253 (/TAS) O00253 (/TAS) O00253 (/TAS)
Regulation of feeding behavior GO:0060259
Any process that modulates the rate, frequency or extent of the behavior associated with the intake of food.
4 O00253 (/IDA) O00253 (/IDA) O00253 (/IDA) O00253 (/IDA)
Regulation of feeding behavior GO:0060259
Any process that modulates the rate, frequency or extent of the behavior associated with the intake of food.
4 O00253 (/IMP) O00253 (/IMP) O00253 (/IMP) O00253 (/IMP)
Neuropeptide signaling pathway GO:0007218
The series of molecular signals generated as a consequence of a peptide neurotransmitter binding to a cell surface receptor.
2 P56473 (/ISO) P56473 (/ISO)
Adult feeding behavior GO:0008343
Feeding behavior in a fully developed and mature organism.
2 P56473 (/IDA) P56473 (/IDA)
Eating behavior GO:0042755
The specific behavior of an organism relating to the intake of food, any substance (usually solid) that can be metabolized by an organism to give energy and build tissue.
2 P56473 (/ISO) P56473 (/ISO)
Regulation of feeding behavior GO:0060259
Any process that modulates the rate, frequency or extent of the behavior associated with the intake of food.
2 P56473 (/ISO) P56473 (/ISO)
Positive regulation of feeding behavior GO:2000253
Any process that activates or increases the frequency, rate or extent of feeding behavior.
2 P56473 (/ISO) P56473 (/ISO)

There are 8 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Extracellular space GO:0005615
That part of a multicellular organism outside the cells proper, usually taken to be outside the plasma membranes, and occupied by fluid.
5 P56413 (/ISS) P56473 (/ISS) P56473 (/ISS) Q9TU18 (/ISS) Q9TU18 (/ISS)
Golgi lumen GO:0005796
The volume enclosed by the membranes of any cisterna or subcompartment of the Golgi apparatus, including the cis- and trans-Golgi networks.
5 P56413 (/ISS) P56473 (/ISS) P56473 (/ISS) Q9TU18 (/ISS) Q9TU18 (/ISS)
Extracellular space GO:0005615
That part of a multicellular organism outside the cells proper, usually taken to be outside the plasma membranes, and occupied by fluid.
4 O00253 (/IDA) O00253 (/IDA) O00253 (/IDA) O00253 (/IDA)
Golgi lumen GO:0005796
The volume enclosed by the membranes of any cisterna or subcompartment of the Golgi apparatus, including the cis- and trans-Golgi networks.
4 O00253 (/IDA) O00253 (/IDA) O00253 (/IDA) O00253 (/IDA)
Extracellular region GO:0005576
The space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane. This term covers the host cell environment outside an intracellular parasite.
2 P56473 (/TAS) P56473 (/TAS)
Extracellular space GO:0005615
That part of a multicellular organism outside the cells proper, usually taken to be outside the plasma membranes, and occupied by fluid.
2 P56473 (/ISO) P56473 (/ISO)
Golgi lumen GO:0005796
The volume enclosed by the membranes of any cisterna or subcompartment of the Golgi apparatus, including the cis- and trans-Golgi networks.
2 P56473 (/ISO) P56473 (/ISO)
Neuronal cell body GO:0043025
The portion of a neuron that includes the nucleus, but excludes cell projections such as axons and dendrites.
2 P56473 (/ISO) P56473 (/ISO)